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Author Details

Parasvi S Patel
Princess Margaret Cancer Centre, University Health Network
2016
16
10
PMIDPaper TitleJournal TitlePublished Year
36928661Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers.Nucleic Acids Res2023
37697435RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.Nucleic Acids Res2023
37454295ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms.Cell Rep2023
35483781Emerging roles of DNA topoisomerases in the regulation of R-loops.Mutat Res Genet Toxicol Environ Mutagen2022
35668135The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness.Nat Cell Biol2022
33440225Strategic Training in Transdisciplinary Radiation Science for the 21st Century (STARS21): 15-Year Evaluation of an Innovative Research Training Program.Int J Radiat Oncol Biol Phys2021
33716297Exploiting synthetic lethality to target BRCA1/2-deficient tumors: where we stand.Oncogene2021
33529165RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.J Clin Invest2021
35008272<i>BRCA1</i> and Metastasis: Outcome of Defective DNA Repair.Cancers (Basel)2021
34196309Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis.J Clin Invest2021
32669707Nucleolar RNA polymerase II drives ribosome biogenesis.Nature2020
29884901Preclinical evaluation of the selective small-molecule UBA1 inhibitor, TAK-243, in acute myeloid leukemia.Leukemia2019
30222135Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis.J Clin Invest2018
30033362Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19.Cell2018
27558965RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation.Nat Commun2016
27357627Advanced Design of Dumbbell-shaped Genetic Minimal Vectors Improves Non-coding and Coding RNA Expression.Mol Ther2016
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Collaborators

Razqallah Hakem
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 12
Brian Raught
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 6
Anne Hakem
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 6
Samah El Ghamrasni
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Otto Sanchez
Ontario Tech University
Co-authored papers 3
Housheng Hansen He
Princess Margaret Cancer Center, University Health Network, University of Toronto
Co-authored papers 2
Fraser Soares
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Rama Khokha
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Hartland W Jackson
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 2
Aaron D Schimmer
Princess Margaret Cancer Centre
Co-authored papers 2
Rose Hurren
Princess Margaret Cancer Centre
Co-authored papers 2
Max Kotlyar
Schroeder Arthritis Institute
Co-authored papers 2
Igor Jurisica
Schroeder Arthritis Institute
Co-authored papers 2
Marcela Gronda
Princess Margaret Cancer Centre
Co-authored papers 2
Fei-Fei Liu
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 1
Robert G Bristow
University of Toronto
Co-authored papers 1
Yi Liang
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Shannon K McDonnell
Mayo Clinic
Co-authored papers 1
Stanley Zhou
Princess Margaret Cancer Research Centre
Co-authored papers 1
Yuzhe Zhang
China University of Mining and Technology
Co-authored papers 1
Miranda Wang
Princess Margaret Cancer Center/University Health Network
Co-authored papers 1
Joseph L Chin
University of Western Ontario
Co-authored papers 1
Amina Zoubeidi
University of British Columbia
Co-authored papers 1
Jennifer Lu
Princess Margaret Cancer Center, University Health Network, University of Toronto
Co-authored papers 1
Jack F Greenblatt
College Street, University of Toronto
Co-authored papers 1
Ming-Sound Tsao
University Health Network, University of Toronto
Co-authored papers 1
Paul C Boutros
University of California los angeles
Co-authored papers 1
Felix Y Feng
UCSF Medical Center-Mount Zion
Co-authored papers 1
Georgia Chenevix-Trench
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