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Author Details
Full Name
Edwin J Weeber
Affiliation
University of South Florida
ORCID
Career Start Year
1997
Papers
116
H Index
54
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
33203220
Quantitative EEG Analysis in Angelman Syndrome: Candidate Method for Assessing Therapeutics.
Clin EEG Neurosci
2023
37315752
Central repeat fragment of reelin leads to active reelin intracellular signaling and rescues cognitive deficits in a mouse model of reelin deficiency.
Cell Signal
2023
36945758
A novel Reelin construct, R36, recovered behavioural deficits in the heterozygous reeler mouse.
Eur J Neurosci
2023
36919335
Reelin and APP Cooperatively Modulate Dendritic Spine Formation <i>In Vitro</i> and <i>In Vivo</i>.
Exp Neurobiol
2023
34410588
Accumulation of C-terminal cleaved tau is distinctly associated with cognitive deficits, synaptic plasticity impairment, and neurodegeneration in aged mice.
Geroscience
2022
35367589
Recovery of Angelman syndrome rat deficits with UBE3A protein supplementation.
Mol Cell Neurosci
2022
36045248
Correction to: Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via A β ligation to β1-integrin conformers.
Cell Death Differ
2022
35863501
Reelin central fragment supplementation improves cognitive deficits in a mouse model of Fragile X Syndrome.
Exp Neurol
2022
33474832
Identification of UBE3A Protein in CSF and Extracellular Space of the Hippocampus Suggest a Potential Novel Function in Synaptic Plasticity.
Autism Res
2021
33531368
Early Developmental EEG and Seizure Phenotypes in a Full Gene Deletion of Ubiquitin Protein Ligase E3A Rat Model of Angelman Syndrome.
eNeuro
2021
32410624
Two forms of CX3CL1 display differential activity and rescue cognitive deficits in CX3CL1 knockout mice.
J Neuroinflammation
2020
31961493
Generation of a Novel Rat Model of Angelman Syndrome with a Complete Ube3a Gene Deletion.
Autism Res
2020
31918761
Evaluation of the safety and tolerability of a nutritional Formulation in patients with ANgelman Syndrome (FANS): study protocol for a randomized controlled trial.
Trials
2020
32066685
Translational outcomes in a full gene deletion of ubiquitin protein ligase E3A rat model of Angelman syndrome.
Transl Psychiatry
2020
31705957
Overexpression of human wtTDP-43 causes impairment in hippocampal plasticity and behavioral deficits in CAMKII-tTa transgenic mouse model.
Mol Cell Neurosci
2020
30963102
The Disease-Associated Chaperone FKBP51 Impairs Cognitive Function by Accelerating AMPA Receptor Recycling.
eNeuro
2019
31253191
Spermidine/spermine-N<sup>1</sup>-acetyltransferase ablation impacts tauopathy-induced polyamine stress response.
Alzheimers Res Ther
2019
30739297
Astaxanthin supplementation modulates cognitive function and synaptic plasticity in young and aged mice.
Geroscience
2019
27990716
Quantitative Measurement of Communication Ability in Children with Angelman Syndrome.
J Appl Res Intellect Disabil
2018
29388081
Loss of Angelman Syndrome Protein E6AP Disrupts a Novel Antagonistic Estrogen-Retinoic Acid Transcriptional Crosstalk in Neurons.
Mol Neurobiol
2018
29737626
Identification of spatiotemporal gait parameters and pressure-related characteristics in children with Angelman syndrome: A pilot study.
J Appl Res Intellect Disabil
2018
28944563
A randomized controlled trial of levodopa in patients with Angelman syndrome.
Am J Med Genet A
2018
27986596
Effects of the synthetic neurosteroid ganaxolone on seizure activity and behavioral deficits in an Angelman syndrome mouse model.
Neuropharmacology
2017
28814801
Strain-dependence of the Angelman Syndrome phenotypes in Ube3a maternal deficiency mice.
Sci Rep
2017
27065802
Reelin Proteolysis Affects Signaling Related to Normal Synapse Function and Neurodegeneration.
Front Cell Neurosci
2016
27546058
Ketone ester supplementation attenuates seizure activity, and improves behavior and hippocampal synaptic plasticity in an Angelman syndrome mouse model.
Neurobiol Dis
2016
25298198
Increased selenoprotein P in choroid plexus and cerebrospinal fluid in Alzheimer's disease brain.
J Alzheimers Dis
2015
25864922
Reelin supplementation recovers synaptic plasticity and cognitive deficits in a mouse model for Angelman syndrome.
Eur J Neurosci
2015
25941167
Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers.
Cell Death Differ
2015
25698445
Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers.
Cell Death Differ
2015
25644714
Very low density lipoprotein receptor regulates dendritic spine formation in a RasGRF1/CaMKII dependent manner.
Biochim Biophys Acta
2015
25741591
RanBP9 at the intersection between cofilin and Aβ pathologies: rescue of neurodegenerative changes by RanBP9 reduction.
Cell Death Dis
2015
24434871
Activity-dependent changes in MAPK activation in the Angelman Syndrome mouse model.
Learn Mem
2014
25491305
An open-label pilot trial of minocycline in children as a treatment for Angelman syndrome.
BMC Neurol
2014
25340851
Fyn tyrosine kinase increases Apolipoprotein E Receptor 2 levels and phosphorylation.
PLoS One
2014
24755222
Ligand-induced homotypic and heterotypic clustering of apolipoprotein E receptor 2.
J Biol Chem
2014
24892761
Extracellular proteolysis of reelin by tissue plasminogen activator following synaptic potentiation.
Neuroscience
2014
24664800
In vivo administration of granulocyte colony-stimulating factor restores long-term depression in hippocampal slices prepared from transgenic APP/PS1 mice.
J Neurosci Res
2014
23104248
Reelin supplementation recovers sensorimotor gating, synaptic plasticity and associative learning deficits in the heterozygous reeler mouse.
J Psychopharmacol
2013
24068831
Dab1 is required for synaptic plasticity and associative learning.
J Neurosci
2013
23607970
Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau.
Biol Psychiatry
2013
23592036
Young APOE4 targeted replacement mice exhibit poor spatial learning and memory, with reduced dendritic spine density in the medial entorhinal cortex.
Learn Mem
2013
22137886
Cotinine enhances the extinction of contextual fear memory and reduces anxiety after fear conditioning.
Behav Brain Res
2012
23060451
APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease.
J Biol Chem
2012
22560727
Spatial and temporal silencing of the human maternal UBE3A gene.
Eur J Paediatr Neurol
2012
21159798
Secretin deficiency causes impairment in survival of neural progenitor cells in mice.
Hum Mol Genet
2011
25083141
Insights into synaptic function from mouse models of human cognitive disorders.
Future Neurol
2011
22254961
Single-crystal cubic silicon carbide: an in vivo biocompatible semiconductor for brain machine interface devices.
Annu Int Conf IEEE Eng Med Biol Soc
2011
22072675
CX3CR1 deficiency leads to impairment of hippocampal cognitive function and synaptic plasticity.
J Neurosci
2011
22174738
Adeno-associated virus-mediated rescue of the cognitive defects in a mouse model for Angelman syndrome.
PLoS One
2011
1 - 50 of 116
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The Rockefeller University
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Hospital for Sick Children
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Mark E Pennesi
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Co-authored papers
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Laura Conover
University of South Florida
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Michael A Rogawski
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David G Birch
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Arthur L Beaudet
Baylor College of Medicine
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Jamey D Marth
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Rebecca D Burdine
Princeton University
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Li-Huei Tsai
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