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Author Details

Edwin J Weeber
University of South Florida
1997
116
54
PMIDPaper TitleJournal TitlePublished Year
33203220Quantitative EEG Analysis in Angelman Syndrome: Candidate Method for Assessing Therapeutics.Clin EEG Neurosci2023
37315752Central repeat fragment of reelin leads to active reelin intracellular signaling and rescues cognitive deficits in a mouse model of reelin deficiency.Cell Signal2023
36945758A novel Reelin construct, R36, recovered behavioural deficits in the heterozygous reeler mouse.Eur J Neurosci2023
36919335Reelin and APP Cooperatively Modulate Dendritic Spine Formation <i>In Vitro</i> and <i>In Vivo</i>.Exp Neurobiol2023
34410588Accumulation of C-terminal cleaved tau is distinctly associated with cognitive deficits, synaptic plasticity impairment, and neurodegeneration in aged mice.Geroscience2022
35367589Recovery of Angelman syndrome rat deficits with UBE3A protein supplementation.Mol Cell Neurosci2022
36045248Correction to: Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via A β ligation to β1-integrin conformers.Cell Death Differ2022
35863501Reelin central fragment supplementation improves cognitive deficits in a mouse model of Fragile X Syndrome.Exp Neurol2022
33474832Identification of UBE3A Protein in CSF and Extracellular Space of the Hippocampus Suggest a Potential Novel Function in Synaptic Plasticity.Autism Res2021
33531368Early Developmental EEG and Seizure Phenotypes in a Full Gene Deletion of Ubiquitin Protein Ligase E3A Rat Model of Angelman Syndrome.eNeuro2021
32410624Two forms of CX3CL1 display differential activity and rescue cognitive deficits in CX3CL1 knockout mice.J Neuroinflammation2020
31961493Generation of a Novel Rat Model of Angelman Syndrome with a Complete Ube3a Gene Deletion.Autism Res2020
31918761Evaluation of the safety and tolerability of a nutritional Formulation in patients with ANgelman Syndrome (FANS): study protocol for a randomized controlled trial.Trials2020
32066685Translational outcomes in a full gene deletion of ubiquitin protein ligase E3A rat model of Angelman syndrome.Transl Psychiatry2020
31705957Overexpression of human wtTDP-43 causes impairment in hippocampal plasticity and behavioral deficits in CAMKII-tTa transgenic mouse model.Mol Cell Neurosci2020
30963102The Disease-Associated Chaperone FKBP51 Impairs Cognitive Function by Accelerating AMPA Receptor Recycling.eNeuro2019
31253191Spermidine/spermine-N<sup>1</sup>-acetyltransferase ablation impacts tauopathy-induced polyamine stress response.Alzheimers Res Ther2019
30739297Astaxanthin supplementation modulates cognitive function and synaptic plasticity in young and aged mice.Geroscience2019
27990716Quantitative Measurement of Communication Ability in Children with Angelman Syndrome.J Appl Res Intellect Disabil2018
29388081Loss of Angelman Syndrome Protein E6AP Disrupts a Novel Antagonistic Estrogen-Retinoic Acid Transcriptional Crosstalk in Neurons.Mol Neurobiol2018
29737626Identification of spatiotemporal gait parameters and pressure-related characteristics in children with Angelman syndrome: A pilot study.J Appl Res Intellect Disabil2018
28944563A randomized controlled trial of levodopa in patients with Angelman syndrome.Am J Med Genet A2018
27986596Effects of the synthetic neurosteroid ganaxolone on seizure activity and behavioral deficits in an Angelman syndrome mouse model.Neuropharmacology2017
28814801Strain-dependence of the Angelman Syndrome phenotypes in Ube3a maternal deficiency mice.Sci Rep2017
27065802Reelin Proteolysis Affects Signaling Related to Normal Synapse Function and Neurodegeneration.Front Cell Neurosci2016
27546058Ketone ester supplementation attenuates seizure activity, and improves behavior and hippocampal synaptic plasticity in an Angelman syndrome mouse model.Neurobiol Dis2016
25298198Increased selenoprotein P in choroid plexus and cerebrospinal fluid in Alzheimer's disease brain.J Alzheimers Dis2015
25864922Reelin supplementation recovers synaptic plasticity and cognitive deficits in a mouse model for Angelman syndrome.Eur J Neurosci2015
25941167Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers.Cell Death Differ2015
25698445Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers.Cell Death Differ2015
25644714Very low density lipoprotein receptor regulates dendritic spine formation in a RasGRF1/CaMKII dependent manner.Biochim Biophys Acta2015
25741591RanBP9 at the intersection between cofilin and Aβ pathologies: rescue of neurodegenerative changes by RanBP9 reduction.Cell Death Dis2015
24434871Activity-dependent changes in MAPK activation in the Angelman Syndrome mouse model.Learn Mem2014
25491305An open-label pilot trial of minocycline in children as a treatment for Angelman syndrome.BMC Neurol2014
25340851Fyn tyrosine kinase increases Apolipoprotein E Receptor 2 levels and phosphorylation.PLoS One2014
24755222Ligand-induced homotypic and heterotypic clustering of apolipoprotein E receptor 2.J Biol Chem2014
24892761Extracellular proteolysis of reelin by tissue plasminogen activator following synaptic potentiation.Neuroscience2014
24664800In vivo administration of granulocyte colony-stimulating factor restores long-term depression in hippocampal slices prepared from transgenic APP/PS1 mice.J Neurosci Res2014
23104248Reelin supplementation recovers sensorimotor gating, synaptic plasticity and associative learning deficits in the heterozygous reeler mouse.J Psychopharmacol2013
24068831Dab1 is required for synaptic plasticity and associative learning.J Neurosci2013
23607970Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau.Biol Psychiatry2013
23592036Young APOE4 targeted replacement mice exhibit poor spatial learning and memory, with reduced dendritic spine density in the medial entorhinal cortex.Learn Mem2013
22137886Cotinine enhances the extinction of contextual fear memory and reduces anxiety after fear conditioning.Behav Brain Res2012
23060451APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease.J Biol Chem2012
22560727Spatial and temporal silencing of the human maternal UBE3A gene.Eur J Paediatr Neurol2012
21159798Secretin deficiency causes impairment in survival of neural progenitor cells in mice.Hum Mol Genet2011
25083141Insights into synaptic function from mouse models of human cognitive disorders.Future Neurol2011
22254961Single-crystal cubic silicon carbide: an in vivo biocompatible semiconductor for brain machine interface devices.Annu Int Conf IEEE Eng Med Biol Soc2011
22072675CX3CR1 deficiency leads to impairment of hippocampal cognitive function and synaptic plasticity.J Neurosci2011
22174738Adeno-associated virus-mediated rescue of the cognitive defects in a mouse model for Angelman syndrome.PLoS One2011
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Collaborators

Jan and Dan Duncan Neurological Research Institute, Baylor College of Medicine
Co-authored papers 7
University of South Florida
Co-authored papers 6
Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 3
Baylor College of Medicine
Co-authored papers 3
Co-authored papers 3
Yale University School of Medicine
Co-authored papers 2
University of South Florida
Co-authored papers 2
Georgetown University
Co-authored papers 2
Emory Center for Neurodegenerative Disease
Co-authored papers 2
The Rockefeller University
Co-authored papers 1
Saint Louis University School of Medicine
Co-authored papers 1
Hospital for Sick Children
Co-authored papers 1
Casey Eye Institute at Oregon Health & Science University (OHSU)
Co-authored papers 1
University of South Florida
Co-authored papers 1
University of California davis
Co-authored papers 1
Retina Foundation of the Southwest
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Co-authored papers 1
Princeton University
Co-authored papers 1
The Picower Institute for Learning and Memory, Massachusetts Institute of Technology
Co-authored papers 1
The Wellcome Trust Sanger Institute
Co-authored papers 1
Cincinnati Children's Hospital Medical Center
Co-authored papers 1
The Hospital for Sick Children, University of Oxford, University of Toronto
Co-authored papers 1
Vanderbilt University Medical Center
Co-authored papers 1
Auburn University, University of Florida, University of Massachusetts Amherst, University of South Carolina, University of South Florida, University of Virginia
Co-authored papers 1
University of Arkansas for Medical Sciences
Co-authored papers 1