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Author Details

Eric J Huang
University of California san francisco
1990
165
73
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37645893Deconstructing intratumoral heterogeneity through multiomic and multiscale analysis of serial sections.bioRxiv2024
36599696Clinical and Neurophysiologic Phenotypes in Neonates With <i>BRAT1</i> Encephalopathy.Neurology2023
37704727A cross-species proteomic map reveals neoteny of human synapse development.Nature2023
37824647Single-cell analysis of prenatal and postnatal human cortical development.Science2023
37210315Disentangling brain vasculature in neurogenesis and neurodegeneration using single-cell transcriptomics.Trends Neurosci2023
36786833Plastin 3 rescues BDNF-TrkB signaling in spinal muscular atrophy.J Cell Biol2023
36602862Astroglial toxicity promotes synaptic degeneration in the thalamocortical circuit in frontotemporal dementia with GRN mutations.J Clin Invest2023
34596066Atypical Young-onset Dementia in Cerebral Thromboangiitis Obliterans: A Case Report.Alzheimer Dis Assoc Disord2022
35731122Right temporal degeneration and socioemotional semantics: semantic behavioural variant frontotemporal dementia.Brain2022
35792478Neuroimmune dysfunction in frontotemporal dementia: Insights from progranulin and C9orf72 deficiency.Curr Opin Neurobiol2022
35420933Comment on "Impact of neurodegenerative diseases on human adult hippocampal neurogenesis".Science2022
35446347Secretory autophagy maintains proteostasis upon lysosome inhibition.J Cell Biol2022
36356576Systematic analysis of the MAPK signaling network reveals MAP3K-driven control of cell fate.Cell Syst2022
36229415Acid sphingomyelinase inhibition improves motor behavioral deficits and neuronal loss in an amyotrophic lateral sclerosis mouse model.BMB Rep2022
36112418Endosomal recycling defects link Huntington's disease with McLeod syndrome.J Cell Biol2022
34981791Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.J Clin Invest2022
34942405Prenatal presentation of multiple anomalies associated with haploinsufficiency for ARID1A.Eur J Med Genet2022
35084970Nests of dividing neuroblasts sustain interneuron production for the developing human brain.Science2022
33219525Diagnostic Accuracy of Amyloid versus <sup>18</sup> F-Fluorodeoxyglucose Positron Emission Tomography in Autopsy-Confirmed Dementia.Ann Neurol2021
33792567ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects.J Clin Invest2021
33762407Positive Controls in Adults and Children Support That Very Few, If Any, New Neurons Are Born in the Adult Human Hippocampus.J Neurosci2021
33693619Comorbid neuropathological diagnoses in early versus late-onset Alzheimer's disease.Brain2021
34344440Processing of progranulin into granulins involves multiple lysosomal proteases and is affected in frontotemporal lobar degeneration.Mol Neurodegener2021
34362731Longitudinal tracking of neuronal mitochondria delineates PINK1/Parkin-dependent mechanisms of mitochondrial recycling and degradation.Sci Adv2021
34228783Label-retention expansion microscopy.J Cell Biol2021
32345721Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant <i>wobbler</i> mice, a model of motor neuron degeneration.Proc Natl Acad Sci U S A2020
31932738The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles.Nat Cell Biol2020
31901251Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma.Cell Stem Cell2020
31776210Loss of HIPK2 Protects Neurons from Mitochondrial Toxins by Regulating Parkin Protein Turnover.J Neurosci2020
31913476Frontotemporal dementia non-sense mutation of progranulin rescued by aminoglycosides.Hum Mol Genet2020
33086038Wnt-Dependent Oligodendroglial-Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury.Neuron2020
33053356Reciprocal Interaction between Vascular Filopodia and Neural Stem Cells Shapes Neurogenesis in the Ventral Telencephalon.Cell Rep2020
32661024A Developmental Analysis of Juxtavascular Microglia Dynamics and Interactions with the Vasculature.J Neurosci2020
32203496Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map.Nat Neurosci2020
30355151RNA Binding Proteins and the Pathogenesis of Frontotemporal Lobar Degeneration.Annu Rev Pathol2019
32699834Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia.Brain Commun2019
31587467Novel and lethal case of cardiac involvement in DNM1L mitochondrial encephalopathy.Am J Med Genet A2019
31626288Astrocytic Tau Deposition Is Frequent in Typical and Atypical Alzheimer Disease Presentations.J Neuropathol Exp Neurol2019
31624869C9orf72-specific phenomena associated with frontotemporal dementia and gastrointestinal symptoms in the absence of TDP-43 aggregation.Acta Neuropathol2019
31227709Immature excitatory neurons develop during adolescence in the human amygdala.Nat Commun2019
31081015Neuropathological correlates of structural and functional imaging biomarkers in 4-repeat tauopathies.Brain2019
30846482Impaired αVβ8 and TGFβ signaling lead to microglial dysmaturation and neuromotor dysfunction.J Exp Med2019
30347188Multisite study of the relationships between antemortem [<sup>11</sup>C]PIB-PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology.Alzheimers Dement2019
30511086Neurons selectively targeted in frontotemporal dementia reveal early stage TDP-43 pathobiology.Acta Neuropathol2019
29453245Early vs late age at onset frontotemporal dementia and frontotemporal lobar degeneration.Neurology2018
30212683Progranulin in the hematopoietic compartment protects mice from atherosclerosis.Atherosclerosis2018
30526879Does Adult Neurogenesis Persist in the Human Hippocampus?Cell Stem Cell2018
29581378HIPK2-Mediated Transcriptional Control of NMDA Receptor Subunit Expression Regulates Neuronal Survival and Cell Death.J Neurosci2018
29513649Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults.Nature2018
29511098Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay.Proc Natl Acad Sci U S A2018
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Collaborators

William W Seeley
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 34
Bruce L Miller
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 31
Amy A Tang
University of California san francisco
Co-authored papers 14
Howard J Rosen
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 14
David H Rowitch
Wellcome Trust-Medical Research Council Stem Cell Institute and.
Co-authored papers 14
Mercedes F Paredes
University of California san francisco
Co-authored papers 12
Adam L Boxer
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 12
Jos?? Manuel Garc??a-Verdugo
Cavanilles Institute, University of Valencia
Co-authored papers 11
Arturo Alvarez-Buylla
University of California san francisco
Co-authored papers 11
Joel H Kramer
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 10
John Q Trojanowski
University of Pennsylvania
Co-authored papers 10
Stephen J DeArmond
Co-authored papers 10
Anna Karydas
Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 9
Michael C Oldham
University of California san francisco
Co-authored papers 8
Arnold R Kriegstein
University of California san francisco
Co-authored papers 8
Giovanni Coppola
David Geffen School of Medicine, University of California los angeles
Co-authored papers 6
Steven Finkbeiner
J. David Gladstone Institutes
Co-authored papers 6
Arantxa Cebrian-Silla
University of California San Francisco
Co-authored papers 6
William J Jagust
Helen Wills Neuroscience Institute, University of California Berkeley
Co-authored papers 6
Robert V Farese
Harvard T.H. Chan School of Public Health
Co-authored papers 6
Li Gan
Helen and Robert Appel Alzheimer's Disease Research Institute
Co-authored papers 5
Sami J Barmada
University of Michigan ann arbor
Co-authored papers 5
Daniel H Geschwind
University of California los angeles
Co-authored papers 5
Jennifer A Cotter
Children's Hospital Los Angeles
Co-authored papers 4
Tobias C Walther
Harvard T. H. Chan School of Public Health
Co-authored papers 3
Charles DeCarli
University of California Davis
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Giancarlo Comi
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Release 1.2