Author details

Full Name

Frances Humby

Affiliation

ORCID

Career Start Year

2007

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
38033364	Attitudes towards technology supported rheumatoid arthritis care: investigating patient- and clinician-perceived opportunities and barriers.		2023
36052336	Editorial: Synovial pathobiology and pathogenesis of inflammatory arthritis.	Frontiers in Medicine	2022
34901062	Editorial: Synovial Tissue: Turning the Page to Precision Medicine in Arthritis?	Frontiers in Medicine	2021
33674419	Fibrocytes in early and long-standing rheumatoid arthritis: a 6-month trial with repeated synovial biopsy, imaging and lung function test.	RMD Open	2021
31421034	Efficacy, Safety, and Sample Quality of Ultrasound-Guided Synovial Needle Biopsy in Clinical Practice and Research: A Prospective Observational Study.	Arthritis Care and Research	2020
32431716	A Pauci-Immune Synovial Pathotype Predicts Inadequate Response to TNFÎ±-Blockade in Rheumatoid Arthritis Patients.	Frontiers in Immunology	2020
32531503	Treatment-resistant synovitis and radiographic progression are increased in elderly-onset rheumatoid arthritis patients: findings from a prospective observational longitudinal early arthritis cohort study.	Seminars in Arthritis and Rheumatism	2020
32637608	Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal.	Sci Adv	2020
33227741	From Personalised Predictions to Targeted Advice: Improving Self-Management in Rheumatoid Arthritis.		2020
31302598	Response to: 'Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients' by Buch .	Annals of the Rheumatic Diseases	2020
30878974	Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients.	Ann Rheum Dis	2019
31582377	Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEA	Annals of the Rheumatic Diseases	2019
31708446	Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4 T Cell Metabolic Rewiring.		2019
30297327	Wrist ultrasound - the model method for grey-scale and power Doppler scoring.	Annals of the Rheumatic Diseases	2019
30761301	Synovial Tissue Sampling in Rheumatological Practice-Past Developments and Future Perspectives.	Frontiers in Medicine	2019
31413866	Six-month prospective trial in early and long-standing rheumatoid arthritis: evaluating disease activity in the wrist through sequential synovial histopathological analysis, RAMRIS magnetic resonance score and EULAR-OMERACT ultrasound score.	RMD Open	2019
30729653	Factors associated with physical activity engagement among adults with rheumatoid arthritis: A cross-sectional study.	Practice Development in Health Care	2019
31371305	Inflammatory cytokines shape a changing DNA methylome in monocytes mirroring disease activity in rheumatoid arthritis.	Annals of the Rheumatic Diseases	2019
31461658	Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes.	Cell Rep	2019
29409140	A Multicenter Retrospective Analysis Evaluating Performance of Synovial Biopsy Techniques in Patients With Inflammatory Arthritis: Arthroscopic Versus Ultrasound-Guided Versus Blind Needle Biopsy.	Arthritis and Rheumatology	2018
30509322	Standardisation of synovial biopsy analyses in rheumatic diseases: a consensus of the EULAR Synovitis and OMERACT Synovial Tissue Biopsy Groups.		2018
30488001	Patient-reported outcomes and safety in patients undergoing synovial biopsy: comparison of ultrasound-guided needle biopsy, ultrasound-guided portal and forceps and arthroscopic-guided synovial biopsy techniques in five centres across Europe.	RMD Open	2018
30567571	Correction to: Standardisation of synovial biopsy analyses in rheumatic diseases: a consensus of the EULAR Synovitis and OMERACT Synovial Tissue Biopsy Groups.		2018
30127058	Mast cells in early rheumatoid arthritis associate with disease severity and support B cell autoantibody production.	Annals of the Rheumatic Diseases	2018
29489833	Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression.	PLoS ONE	2018
29720240	Integrative analysis reveals CD38 as a therapeutic target for plasma cell-rich pre-disease and established rheumatoid arthritis and systemic lupus erythematosus.	Arthritis Res Ther	2018
27991858	EULAR definition of arthralgia suspicious for progression to rheumatoid arthritis.	Annals of the Rheumatic Diseases	2017
28935945	Synovial tissue research: a state-of-the-art review.	Nature reviews. Rheumatology	2017
28711880	The Relationship Between Synovial Pathobiology and Magnetic Resonance Imaging Abnormalities in Rheumatoid Arthritis: A Systematic Review.	Journal of Rheumatology	2017
28701760	Synovial tissue research: a state-of-the-art review.	Nature reviews. Rheumatology	2017
28516086	Can Synovial Pathobiology Integrate with Current Clinical and Imaging Prediction Models to Achieve Personalized Health Care in Rheumatoid Arthritis?	Frontiers in Medicine	2017
29255214	Corrigendum: Synovial tissue research: a state-of-the-art review.	Nature reviews. Rheumatology	2017
26034155	Evaluation of Minimally Invasive, Ultrasound-guided Synovial Biopsy Techniques by the OMERACT Filter--Determining Validation Requirements.	Journal of Rheumatology	2016
26792343	Higher expression of TNFÎ±-induced genes in the synovium of patients with early rheumatoid arthritis correlates with disease activity, and predicts absence of response to first line therapy.		2016
27463825	Ultrasound-guided synovial biopsy of the wrist does not alter subsequent clinical or ultrasound disease activity assessments: a prospective study for incorporation of imaging in clinical trials.	Clinical and Experimental Rheumatology	2016
24336336	Ultrasound-guided synovial biopsy: a safe, well-tolerated and reliable technique for obtaining high-quality synovial tissue from both large and small joints in early arthritis patients.	Annals of the Rheumatic Diseases	2015
25889955	Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early Rheumatoid Arthritis: an observational study.		2015
26097225	Use of ultrasound-guided small joint biopsy to evaluate the histopathologic response to rheumatoid arthritis therapy: recommendations for application to clinical trials.	Arthritis and Rheumatology	2015
26022188	Ultrasound-guided synovial biopsy: a systematic review according to the OMERACT filter and recommendations for minimal reporting standards in clinical studies.	Rheumatology	2015
24764267	High expression levels of the B cell chemoattractant CXCL13 in rheumatoid synovium are a marker of severe disease.	Rheumatology	2014
23268369	Epstein-Barr virus persistence and infection of autoreactive plasma cells in synovial lymphoid structures in rheumatoid arthritis.	Annals of the Rheumatic Diseases	2013
23492740	New learnings on the pathophysiology of RA from synovial biopsies.	Current Opinion in Rheumatology	2013
22089057	Mycophenolate mofetil inducing remission of lupus enteritis.	Lupus	2012
21847543	Synovial tissue heterogeneity and peripheral blood biomarkers.	Current Rheumatology Reports	2011
20193005	Secondary and ectopic lymphoid tissue responses in rheumatoid arthritis: from inflammation to autoimmunity and tissue damage/remodeling.	Immunological Reviews	2010
19143467	Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synovium.	PLoS Medicine	2009
18975336	Mature antigen-experienced T helper cells synthesize and secrete the B cell chemoattractant CXCL13 in the inflammatory environment of the rheumatoid joint.		2008
18524807	A synovial pathergy reaction leading to a pseudo-septic arthritis and a diagnosis of BehÃ§et's disease.	Rheumatology	2008
17878393	Activation-induced cytidine deaminase expression in follicular dendritic cell networks and interfollicular large B cells supports functionality of ectopic lymphoid neogenesis in autoimmune sialoadenitis and MALT lymphoma in SjÃ¶gren's syndrome.	Journal of Immunology	2007
17317617	The synovial membrane as a prognostic tool in rheumatoid arthritis.	Autoimmunity Reviews	2007