Author details

Full Name

John Bowes

Affiliation

ORCID

Career Start Year

2004

Papers

100

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37516563	Genetic Studies Investigating Susceptibility to Psoriatic Arthritis: A Narrative Review.		2023
35861400	Association between psoriatic disease and lifestyle factors and comorbidities: cross-sectional analysis and Mendelian randomization.	Rheumatology	2023
38010198	Using polygenic risk scores to aid diagnosis of patients with early inflammatory arthritis: results from the Norfolk Arthritis Register.		2023
37873414	GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets.	medRxiv	2023
37154150	Validation of lung cancer polygenic risk scores in a high-risk case-control cohort.		2023
37212253	Optimization of polygenic risk scores in BRCA1/2 pathogenic variant heterozygotes in epithelial ovarian cancer.		2023
36696131	Association of Lipid-Lowering Drugs With Risk of Psoriasis: A Mendelian Randomization Study.		2023
36546557	Genome-wide association analysis identifies a susceptibility locus for sporadic vestibular schwannoma at 9p21.		2023
36987655	EULAR study group on 'MHC-I-opathy': identifying disease-overarching mechanisms across disciplines and borders.	Ann Rheum Dis	2023
36600188	Genetically proxied TYK2 inhibition is associated with reduced sarcoidosis susceptibility.		2023
35094092	Association with HLA-DRÎ²1 position 37 distinguishes juvenile dermatomyositis from adult-onset myositis.	Hum Mol Genet	2022
35507331	Comparative Genetic Analysis of Psoriatic Arthritis and Psoriasis for the Discovery of Genetic Risk Factors and Risk Prediction Modeling.	Arthritis Rheumatol	2022
36289648	Omics and Multi-Omics Analysis for the Early Identification and Improved Outcome of Patients with Psoriatic Arthritis.	Biomedicines	2022
36333501	Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis.	Nat Genet	2022
35995490	Separating the effects of childhood and adult body size on inflammatory arthritis: a Mendelian randomisation study.	RMD Open	2022
35468805	HLA-DRB1 haplotypes predict cardiovascular mortality in inflammatory polyarthritis independent of CRP and anti-CCP status.		2022
33106285	Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms.	Ann Rheum Dis	2021
33958779	Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney.	Nat Genet	2021
34004033	Extending the allelic spectrum at noncoding risk loci of orofacial clefting.	Hum Mutat	2021
32778885	Using functional genomics to advance the understanding of psoriatic arthritis.	Rheumatology	2020
32196497	Exploring the overlap between rheumatoid arthritis susceptibility loci and long non-coding RNA annotations.	PLoS ONE	2020
32887683	Genomic risk scores for juvenile idiopathic arthritis and its subtypes.	Ann Rheum Dis	2020
33239102	Genetic feature engineering enables characterisation of shared risk factors in immune-mediated diseases.	Genome Medicine	2020
30964579	Genetic counseling, 2030: An on-demand service tailored to the needs of a price conscious, genetically literate, and busy world.	J Genet Couns	2019
31138531	Focused HLA analysis in Caucasians with myositis identifies significant associations with autoantibody subgroups.	Ann Rheum Dis	2019
29426059	Brief Report: The Genetic Profile of Rheumatoid Factor-Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis.	Arthritis Rheumatol	2018
30107595	The prevalence of co-morbidities and their impact on physical activity in people with inflammatory rheumatic diseases compared with the general population: results from the UK Biobank.	Rheumatology	2018
30467309	Molecular insights into genome-wide association studies of chronic kidney disease-defining traits.	Nat Commun	2018
27998952	Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases.	Ann Rheum Dis	2017
28821532	Cross-phenotype association mapping of the MHC identifies genetic variants that differentiate psoriatic arthritis from psoriasis.	Ann Rheum Dis	2017
28501801	A rare coding allele in <i>IFIH1</i> is protective for psoriatic arthritis.	Ann Rheum Dis	2017
29221136	and are disease-specific biomarkers for psoriatic arthritis susceptibility.	Oncotarget	2017
28087736	Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip Â± cleft palate and cleft palate only.	Hum Mol Genet	2017
28086002	Immune-Array Analysis in Sporadic Inclusion Body Myositis Reveals HLA-DRB1 Amino Acid Heterogeneity Across the Myositis Spectrum.	Arthritis Rheumatol	2017
26255310	Identifying a novel locus for psoriatic arthritis.	Rheumatology	2016
27109064	Major histocompatibility complex harbors widespread genotypic variability of non-additive risk of rheumatoid arthritis including epistasis.	Scientific Reports	2016
27016051	Replication of a distinct psoriatic arthritis risk variant at the IL23R locus.	Annals of the Rheumatic Diseases	2016
26830904	Association of Toll-like receptor 4 (TLR4) with chronic plaque type psoriasis and psoriatic arthritis.	Archives of Dermatological Research	2016
26895230	Replication of Associations of Genetic Loci Outside the HLA Region With Susceptibility to Anti-Cyclic Citrullinated Peptide-Negative Rheumatoid Arthritis.	Arthritis and Rheumatology	2016
26362759	Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups.	Ann Rheum Dis	2016
25124732	Identification of loci associated with late-onset psoriasis using dense genotyping of immune-related regions.	British Journal of Dermatology	2015
25923216	PTPN22 is associated with susceptibility to psoriatic arthritis but not psoriasis: evidence for a further PsA-specific risk locus.	Annals of the Rheumatic Diseases	2015
25651891	Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis.	Nature Communications	2015
25849893	TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits.	PLoS One	2015
26053495	Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls.	Nature Genetics	2015
26220137	Corrigendum: Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls.	Nature Genetics	2015
26145464	Corrigendum: Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis.	Nature Communications	2015
24092415	A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk.	Ann Rheum Dis	2015
24532676	High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci.	Ann Rheum Dis	2015
24656864	Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity.	Am J Hum Genet	2014