Author details

Full Name

Aparna Nathan

Affiliation

ORCID

Career Start Year

2015

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37502994	The T cell receptor sequence influences the likelihood of T cell memory formation.	bioRxiv	2023
38036783	Dynamic regulatory elements in single-cell multimodal data implicate key immune cell states enriched for autoimmune disease heritability.		2023
37938773	Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes.		2023
38014313	Identifying genetic variants that influence the abundance of cell states in single-cell data.		2023
37805522	Immunosuppression causes dynamic changes in expression QTLs in psoriatic skin.		2023
37085594	Single-cell genomics meets human genetics.	Nat Rev Genet	2023
37461650	Structure-based network analysis predicts mutations associated with inherited retinal disease.		2023
37196361	Methods and Insights from Single-Cell Expression Quantitative Trait Loci.	Annu Rev Genomics Hum Genet	2023
37066336	The Chromatin Landscape of Pathogenic Transcriptional Cell States in Rheumatoid Arthritis.	bioRxiv	2023
36993527	Clonal associations of lymphocyte subsets and functional states revealed by single cell antigen receptor profiling of T and B cells in rheumatoid arthritis synovium.	bioRxiv	2023
36993194	Mapping the dynamic genetic regulatory architecture of <i>HLA</i> genes at single-cell resolution.	medRxiv	2023
37425785	History of tuberculosis disease is associated with genetic regulatory variation in Peruvians.	medRxiv	2023
35177831	Repertoire analyses reveal T cell antigen receptor sequence features that influence T cell fate.	Nat Immunol	2022
35545678	Single-cell eQTL models reveal dynamic T cell state dependence of disease loci.	Nature	2022
34675423	Co-varying neighborhood analysis identifies cell populations associated with phenotypes of interest from single-cell transcriptomics.	Nat Biotechnol	2022
35005693	Maximizing statistical power to detect differentially abundant cell states with scPOST.	Cell Rep Methods	2021
33879239	IFN-Î³ and TNF-Î± drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation.	Genome Med	2021
33558674	Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals cross-diagnostic and diagnosis-specific RNA expression changes in major psychiatric disorders.	Neuropsychopharmacology	2021
34031617	Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease.	Nat Immunol	2021
34620862	Efficient and precise single-cell reference atlas mapping with Symphony.	Nat Commun	2021
32793902	IFN- Î³ and TNF- Î± drive a CXCL10 + CCL2 + macrophage phenotype expanded in severe COVID-19 and other diseases with tissue inflammation.	bioRxiv	2020
32325033	BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.	Cell Syst	2020
32061139	Associations between neighborhood-level factors and opioid-related mortality: A multi-level analysis using death certificate data.	Addiction	2020
32853540	BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.	Cell Syst	2020
31430664	Multimodal single-cell approaches shed light on T cell heterogeneity.	Curr Opin Immunol	2019
30737409	Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions.	Nat Commun	2019
30545857	Comprehensive functional genomic resource and integrative model for the human brain.	Science	2018
26131725	Design of Protein-Peptide Interaction Modules for Assembling Supramolecular Structures in Vivo and in Vitro.	ACS Chemical Biology	2015