Skip to Main Content

Author Details

Georgios Skiniotis
Stanford University School of Medicine
1999
119
50
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36411392Insights into distinct signaling profiles of the µOR activated by diverse agonists.Nat Chem Biol2023
37160876Structural basis for activation of CB1 by an endocannabinoid analog.Nat Commun2023
37290962Hexahydroquinoline Derivatives Are Selective Agonists for the Adhesion G Protein-Coupled Receptor ADGRG1/GPR56.Mol Pharmacol2023
36993214Time-resolved cryo-EM of G protein activation by a GPCR.bioRxiv2023
36931277Structures of Ric-8B in complex with Gα protein folding clients reveal isoform specificity mechanisms.Structure2023
36450356Structure-based design of bitopic ligands for the µ-opioid receptor.Nature2023
34281791Drug discovery in the era of cryo-electron microscopy.Trends Biochem Sci2022
35804245Author Correction: Plasticity in ligand recognition at somatostatin receptors.Nat Struct Mol Biol2022
35687850Development of OPLS-AA/M Parameters for Simulations of G Protein-Coupled Receptors and Other Membrane Proteins.J Chem Theory Comput2022
35418682The tethered peptide activation mechanism of adhesion GPCRs.Nature2022
35385593Structure-Based Evolution of G Protein-Biased μ-Opioid Receptor Agonists.Angew Chem Int Ed Engl2022
36396979Structure determination of inactive-state GPCRs with a universal nanobody.Nat Struct Mol Biol2022
36171289Bespoke library docking for 5-HT<sub>2A</sub> receptor agonists with antidepressant activity.Nature2022
36064945Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns.Nat Commun2022
36087581Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD.Neuron2022
34880492Structure and mechanism of the SGLT family of glucose transporters.Nature2022
35241813The oxytocin signaling complex reveals a molecular switch for cation dependence.Nat Struct Mol Biol2022
35210615Plasticity in ligand recognition at somatostatin receptors.Nat Struct Mol Biol2022
35061538Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins.Sci Adv2022
34194039G-protein activation by a metabotropic glutamate receptor.Nature2021
33606986Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells.Cell2021
34862384Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex.Nat Commun2021
34433062Structural insights into GIRK2 channel modulation by cholesterol and PIP<sub>2</sub>.Cell Rep2021
34216564Structural basis for the constitutive activity and immunomodulatory properties of the Epstein-Barr virus-encoded G protein-coupled receptor BILF1.Immunity2021
34087182Structure of the visual signaling complex between transducin and phosphodiesterase 6.Mol Cell2021
34194040Asymmetric activation of the calcium-sensing receptor homodimer.Nature2021
32126208Structures of Gα Proteins in Complex with Their Chaperone Reveal Quality Control Mechanisms.Cell Rep2020
31724694A non-canonical monovalent zinc finger stabilizes the integration of Cfp1 into the H3K4 methyltransferase complex COMPASS.Nucleic Acids Res2020
31945772Structure of the M2 muscarinic receptor-β-arrestin complex in a lipid nanodisc.Nature2020
31945771Structure of the neurotensin receptor 1 in complex with β-arrestin 1.Nature2020
33007200Structure of the Visual Signaling Complex between Transducin and Phosphodiesterase 6.Mol Cell2020
32946782Structure of a Hallucinogen-Activated Gq-Coupled 5-HT<sub>2A</sub> Serotonin Receptor.Cell2020
32580208Structures of metabotropic GABA<sub>B</sub> receptor.Nature2020
32732395Structural insights into differences in G protein activation by family A and family B GPCRs.Science2020
32413291GemSpot: A Pipeline for Robust Modeling of Ligands into Cryo-EM Maps.Structure2020
32297861Limited dishevelled/Axin oligomerization determines efficiency of Wnt/β-catenin signal transduction.Elife2020
30639101Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex.Cell2019
32296768Assessment of Biased Agonism among Distinct Synthetic Cannabinoid Receptor Agonist Scaffolds.ACS Pharmacol Transl Sci2019
31243822Self-Assembly Behavior and Application of Terphenyl-Cored Trimaltosides for Membrane-Protein Studies: Impact of Detergent Hydrophobic Group Geometry on Protein Stability.Chemistry2019
31243364Conformational transitions of a neurotensin receptor 1-Gi1 complex.Nature2019
31300275Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation.Mol Cell2019
30814739Author Correction: Structural insights into the activation of metabotropic glutamate receptors.Nature2019
31073061Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes.Science2019
30675062Structural insights into the activation of metabotropic glutamate receptors.Nature2019
29677516Structural Basis for Teneurin Function in Circuit-Wiring: A Toxin Motif at the Synapse.Cell2018
30213947Development of an antibody fragment that stabilizes GPCR/G-protein complexes.Nat Commun2018
30100186Structure and Conformational Dynamics of a COMPASS Histone H3K4 Methyltransferase Complex.Cell2018
29899455Structure of the µ-opioid receptor-G<sub>i</sub> protein complex.Nature2018
30377372De novo computational RNA modeling into cryo-EM maps of large ribonucleoprotein complexes.Nat Methods2018
30270175Structural Analysis of the Ash2L/Dpy-30 Complex Reveals a Heterogeneity in H3K4 Methylation.Structure2018
  • 1 - 50 of 119

Recommended Authors

Fred Hutchinson Cancer Center
Career Start Year 2012
Number of shared co-authors 5
Fred Hutchinson Cancer Center
Career Start Year 2007
Number of shared co-authors 5
National Cancer Institute, National Institutes of Health
Career Start Year 2007
Number of shared co-authors 1
The Hebrew University of Jerusalem
Career Start Year 2007
Number of shared co-authors 1
Korea Advanced Institute of Science and Technology (KAIST)
Career Start Year 2006
Number of shared co-authors 1
University of Washington
Career Start Year 2006
Number of shared co-authors 3
Howard Hughes Medical Institute
Career Start Year 2004
Number of shared co-authors 1
The Scripps Research Institute
Career Start Year 2003
Number of shared co-authors 2
University of Chinese Academy of Sciences
Career Start Year 2003
Number of shared co-authors 0
Institute of Biological Information Processing (Structural Biochemistry)
Career Start Year 2003
Number of shared co-authors 1
Leibniz-Institut fur Virologie (LIV)
Career Start Year 2001
Number of shared co-authors 1
Florida State University
Career Start Year 2000
Number of shared co-authors 0
Harvard Medical School
Career Start Year 2000
Number of shared co-authors 1
Pennsylvania State University College of Medicine
Career Start Year 1998
Number of shared co-authors 1
Quantitative Bioscience Institute, University of California san francisco
Career Start Year 1997
Number of shared co-authors 8
University of Texas Southwestern Medical Center
Career Start Year 1993
Number of shared co-authors 1
University of Colorado Boulder
Career Start Year 1993
Number of shared co-authors 0
Baylor College of Medicine
Career Start Year 1993
Number of shared co-authors 1
Bridge Institute, University of Southern California
Career Start Year 1991
Number of shared co-authors 6
University of California Berkeley
Career Start Year 1989
Number of shared co-authors 1
Ecole Polytechnique Federale de Lausanne (EPFL), University of Lausanne
Career Start Year 1988
Number of shared co-authors 0
iHuman Institute, ShanghaiTech University
Career Start Year 1988
Number of shared co-authors 6
Albert Einstein College of Medicine
Career Start Year 1988
Number of shared co-authors 1
New York University Grossman School of Medicine
Career Start Year 1985
Number of shared co-authors 1
University of California berkeley
Career Start Year 1982
Number of shared co-authors 0
Zuckerman Mind Brain Behaviour Institute
Career Start Year 1982
Number of shared co-authors 0
Sackler School of Medicine, Tel Aviv University
Career Start Year 1980
Number of shared co-authors 0
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Career Start Year 1977
Number of shared co-authors 9
Columbia University
Career Start Year 1968
Number of shared co-authors 1
Vanderbilt University
Career Start Year 1954
Number of shared co-authors 1

Collaborators

Stanford University School of Medicine
Co-authored papers 28
Stanford University School of Medicine
Co-authored papers 16
Co-authored papers 8
Northwestern University Feinberg School of Medicine
Co-authored papers 7
Stanford University School of Medicine
Co-authored papers 5
Stanford University School of Medicine
Co-authored papers 5
UNC Chapel Hill School of Medicine
Co-authored papers 5
University of Michigan ann arbor
Co-authored papers 5
University of North Carolina at Chapel Hill
Co-authored papers 4
Co-authored papers 4
University of North Carolina School of Medicine
Co-authored papers 3
Co-authored papers 3
Institute for Research in Immunology and Cancer, Universite de Montreal
Co-authored papers 2
Eshelman School of Pharmacy, University of North Carolina
Co-authored papers 2
Co-authored papers 2
Blavatnik Institute, Harvard Medical School
Co-authored papers 2
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 2
Utrecht University
Co-authored papers 2
Co-authored papers 2
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 2
University of North Carolina School of Medicine
Co-authored papers 2
Stanford University
Co-authored papers 1
Quantitative Biosciences Institute (QBI), University of California san francisco
Co-authored papers 1
University of Michigan ann arbor
Co-authored papers 1
University of North Carolina School of Medicine
Co-authored papers 1
University of North Carolina School of Medicine
Co-authored papers 1
Co-authored papers 1
Department of Pharmaceutical Technology and Biopharmacy, University of Groningen
Co-authored papers 1
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 1
Max Planck Institute of Biochemistry
Co-authored papers 1