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Author Details

Ryan G Lim
2008
19
13
PMIDPaper TitleJournal TitlePublished Year
36547263An altered extracellular matrix-integrin interface contributes to Huntington's disease-associated CNS dysfunction in glial and vascular cells.Hum Mol Genet2023
37807512Transplanted human neural stem cells rescue phenotypes in zQ175 Huntington's disease mice and innervate the striatum.Mol Ther2023
36764301Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects.Neuron2023
35115730Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines.Nat Neurosci2022
36590162Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits.iScience2022
36543778Huntington disease oligodendrocyte maturation deficits revealed by single-nucleus RNAseq are rescued by thiamine-biotin supplementation.Nat Commun2022
33945510Huntington's disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization.J Clin Invest2021
32109367Aberrant Development Corrected in Adult-Onset Huntington's Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation.Stem Cell Reports2020
31696228Treatment with JQ1, a BET bromodomain inhibitor, is selectively detrimental to R6/2 Huntington's disease mice.Human Molecular Genetics2020
31088970IKKβ slows Huntington's disease progression in R6/1 mice.Proc Natl Acad Sci U S A2019
29199020The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.Cell Syst2018
29116112A Comparison of mRNA Sequencing with Random Primed and 3'-Directed Libraries.Sci Rep2017
28526555Modeling Psychomotor Retardation using iPSCs from MCT8-Deficient Patients Indicates a Prominent Role for the Blood-Brain Barrier.Cell Stem Cell2017
28514657Huntington's Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits.Cell Reports2017
27427231SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models.Cell Chem Biol2016
22768956Characterization of cholesterol crystals in atherosclerotic plaques using stimulated Raman scattering and second-harmonic generation microscopy.Biophysical Journal2012
21949051Identification of cholesterol crystals in plaques of atherosclerotic mice using hyperspectral CARS imaging.Journal of Lipid Research2011
20208058Multimodal CARS microscopy determination of the impact of diet on macrophage infiltration and lipid accumulation on plaque formation in ApoE-deficient mice.Journal of Lipid Research2010
18209122Nondestructive imaging of live human keloid and facial tissue using multiphoton microscopy.2008
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Smidt Heart Institute, Cedars-Sinai Medical Center
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J. David Gladstone Institutes
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J. David Gladstone Institutes
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Oregon Health Sciences University
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University of California San Francisco
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Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
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David Geffen School of Medicine, University of California los angeles
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