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Author Details

Alan Ashworth
UCSF Helen Diller Family Comprehensive Cancer Center
1982
525
127
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
34323016ADP-ribosyltransferases, an update on function and nomenclature.FEBS J2022
35439318A Whole-Genome CRISPR Screen Identifies AHR Loss as a Mechanism of Resistance to a PARP7 Inhibitor.Mol Cancer Ther2022
35217172Hypoxia Is a Dominant Remodeler of the Effector T Cell Surface Proteome Relative to Activation and Regulatory T Cell Suppression.Mol Cell Proteomics2022
35169801The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and X-ray diffraction at room temperature.bioRxiv2022
35022323Validation of Anticorrelated TGFβ Signaling and Alternative End-Joining DNA Repair Signatures that Predict Response to Genotoxic Cancer Therapy.Clin Cancer Res2022
34562545Incidence of candidaemia in prolonged venovenous extracorporeal membrane oxygenation.J Hosp Infect2022
32785646Common Susceptibility Loci for Male Breast Cancer.J Natl Cancer Inst2021
33853786Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking.Sci Adv2021
34591612A protein interaction landscape of breast cancer.Science2021
34326322An integrated functional and clinical genomics approach reveals genes driving aggressive metastatic prostate cancer.Nat Commun2021
34172499ATR Inhibitors and Paclitaxel in Melanoma.Clin Cancer Res2021
33323380A Very Long-Acting PARP Inhibitor Suppresses Cancer Cell Growth in DNA Repair-Deficient Tumor Models.Cancer Res2021
32662063The evolution of evidence-based medicine in critical care: have we left 'time to defecation' behind?Anaesthesia2021
32221288Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking.Nat Commun2020
31970800Venoarterial extracorporeal membrane oxygenation for postcardiotomy cardiogenic shock-A six-year service evaluation.Artif Organs2020
31777327Microbial contamination of heater cooler units used in extracorporeal membrane oxygenation is not aerosolized into the environment: A single-center experience.Infect Control Hosp Epidemiol2020
32046759Correction to: Timing of pubertal stages and breast cancer risk: the Breakthrough Generations Study.Breast Cancer Res2020
32071145Transcription-Associated Cyclin-Dependent Kinases as Targets and Biomarkers for Cancer Therapy.Cancer Discov2020
31712683Synthetic lethality as an engine for cancer drug target discovery.Nat Rev Drug Discov2020
31949161A network analysis to identify mediators of germline-driven differences in breast cancer prognosis.Nat Commun2020
33077732Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNA.Nat Commun2020
32585905Klotho and the Treatment of Human Malignancies.Cancers (Basel)2020
32696317Parity reduces mammary repopulating activity but does not affect mammary stem cells defined as CD24â¿¿+â¿¿CD29/CD49fhi in mice.Breast Cancer Res Treat2020
32353859A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.Nature2020
32139151An integrated molecular profile of endometrioid ovarian cancer.Gynecol Oncol2020
32402285HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer.Cell Rep2020
32427987Correction: A chemical inhibitor of PPM1D that selectively kills cells overexpressing PPM1D.Oncogene2020
30584261Response to 'Comment on 'Domestic light at night and breast cancer risk: a prospective analysis of 105â¿¿000 UK women in the Generations Study".Br J Cancer2019
31266829DNA-Dependent Protein Kinase Drives Prostate Cancer Progression through Transcriptional Regulation of the Wnt Signaling Pathway.Clin Cancer Res2019
31546756Klotho: A Major Shareholder in Vascular Aging Enterprises.Int J Mol Sci2019
31042381Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity.J Med Chem2019
30656664Peri-operative extracorporeal cardiopulmonary resuscitation.Anaesthesia2019
30655555A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK4/6 inhibitors.Sci Rep2019
30589644PARP inhibition enhances tumor cell-intrinsic immunity in ERCC1-deficient non-small cell lung cancer.J Clin Invest2019
28830912Mapping genetic vulnerabilities reveals BTK as a novel therapeutic target in oesophageal cancer.Gut2018
30131505Author Correction: Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness.Sci Rep2018
29995861Reprogramming human T cell function and specificity with non-viral genome targeting.Nature2018
29955768Targeting Tropomyosin Receptor Kinase in Cutaneous CYLD Defective Tumors With Pegcantratinib: The TRAC Randomized Clinical Trial.JAMA Dermatol2018
29955114Synthetic lethal therapies for cancer: what's next after PARP inhibitors?Nat Rev Clin Oncol2018
30033370Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.Cell2018
30006631Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness.Sci Rep2018
30340047Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.Cell2018
30449619Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function.Cell2018
30365555Correction: Correction: CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.PLoS One2018
30327568Response to 'Comment on 'Domestic light at night and breast cancer risk: a prospective analysis of 105â¿¿000 UK women in the Generations Study".Br J Cancer2018
29447131DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade.J Clin Invest2018
29360812Domestic light at night and breast cancer risk: a prospective analysis of 105â¿¿000 UK women in the Generations Study.Br J Cancer2018
29444438Commonly Occurring Cell Subsets in High-Grade Serous Ovarian Tumors Identified by Single-Cell Mass Cytometry.Cell Rep2018
29748565Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance.Nat Commun2018
29634540Perioperative Extracorporeal Cardiopulmonary Resuscitation: The Defibrillator of the 21st Century?: A Case Report.A A Pract2018
  • 1 - 50 of 525

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Collaborators

Jorge S Reis-Filho
Memorial Sloan-Kettering Cancer Center
Co-authored papers 75
Alan Mackay
Co-authored papers 60
Maryou B Lambros
The Institute of Cancer Research
Co-authored papers 41
Montserrat Garcia-Closas
National Cancer Institute
Co-authored papers 36
Douglas F Easton
University of Cambridge
Co-authored papers 34
Jenny Chang-Claude
German Cancer Research Center (DKFZ)
Co-authored papers 33
Paul D P Pharoah
Center for Cancer Genetic Epidemiology, University of Cambridge
Co-authored papers 33
Alison M Dunning
Co-authored papers 33
Graham G Giles
Co-authored papers 32
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Mayo Clinic
Co-authored papers 32
Georgia Chenevix-Trench
QIMR Berghofer Medical Research Institute
Co-authored papers 32
Per Hall
Co-authored papers 32
Javier Ben??tez
Instituto de Salud Carlos III
Co-authored papers 31
Roger L Milne
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Irene L Andrulis
University of Toronto
Co-authored papers 31
Stephen J Chanock
National Cancer Institute, National Institutes of Health
Co-authored papers 31
Peter A Fasching
Otto-Friedrich-University Bamberg
Co-authored papers 31
Børge G Nordestgaard
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Diether Lambrechts
Co-authored papers 30
Jolanta Lissowska
The M. Sklodowska-Curie Cancer Center and Institute of Oncology
Co-authored papers 29
Jonine D Figueroa
The Usher Institute, The University of Edinburgh
Co-authored papers 28
Julia A Knight
Co-authored papers 28
Janet E Olson
Mayo Clinic
Co-authored papers 27
Jan Lubinski
Pomeranian Medical University
Co-authored papers 27
Hoda Anton-Culver
University of California irvine
Co-authored papers 27
Caroline Seynaeve
Erasmus Medical Center
Co-authored papers 26
Paolo Radice
Ospedale Circolo e Fondazione Macchi
Co-authored papers 26
Vessela N Kristensen
Faculty of Clinical Medicine, University of Oslo
Co-authored papers 24
Christopher A Haiman
University of Southern California
Co-authored papers 23
Loic Le Marchand
Co-authored papers 22
Release 1.2