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Author Details

Hiroyuki Mori
Institute for Life and Medical Sciences, Kyoto University
1989
63
27
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36151494A Photo-Crosslinking Approach to Monitoring the Assembly of an LptD Intermediate with LptE in a Living Cell.Methods Mol Biol2022
36209828Inner membrane YfgM-PpiD heterodimer acts as a functional unit that associates with the SecY/E/G translocon and promotes protein translocation.J Biol Chem2022
34260076Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection.EMBO J2021
30851405A photo-cross-linking approach to monitor protein dynamics in living cells.Biochim Biophys Acta Gen Subj2020
31957229Tree of motility - A proposed history of motility systems in the tree of life.Genes Cells2020
33320090Fine interaction profiling of VemP and mechanisms responsible for its translocation-coupled arrest-cancelation.Elife2020
33093205Reversible autoinhibitory regulation of <i>Escherichia coli</i> metallopeptidase BepA for selective β-barrel protein degradation.Proc Natl Acad Sci U S A2020
30531155Heat shock transcription factor Ï¿<sup>32</sup> defective in membrane transport can be suppressed by transposon insertion into genes encoding a restriction enzyme subunit or a putative autotransporter in Escherichia coli.Genes Genet Syst2019
29317498Identification and characterization of a translation arrest motif in VemP by systematic mutational analysis.J Biol Chem2018
29790986Monitoring substrate enables real-time regulation of a protein localization pathway.FEMS Microbiol Lett2018
29158258A photo-cross-linking approach to monitor folding and assembly of newly synthesized proteins in a living cell.J Biol Chem2018
28960545The TPR domain of BepA is required for productive interaction with substrate proteins and the β-barrel assembly machinery complex.Mol Microbiol2017
28467902Tunnel Formation Inferred from the I-Form Structures of the Proton-Driven Protein Secretion Motor SecDF.Cell Rep2017
27052372A Novel SRP Recognition Sequence in the Homeostatic Control Region of Heat Shock Transcription Factor Ͽ32.Sci Rep2016
26392525Nascent chain-monitored remodeling of the Sec machinery for salinity adaptation of marine bacteria.Proc Natl Acad Sci U S A2015
26447507Roles of the membrane-reentrant β-hairpin-like loop of RseP protease in selective substrate cleavage.Elife2015
24368747Conformational variation of the translocon enhancing chaperone SecDF.J Struct Funct Genomics2014
25466392Crystal structure of Escherichia coli YidC, a membrane protein chaperone and insertase.Sci Rep2014
24739968Structural basis of Sec-independent membrane protein insertion by YidC.Nature2014
21562494Structure and function of a membrane component SecDF that enhances protein export.Nature2011
21810987Post-liberation cleavage of signal peptides is catalyzed by the site-2 protease (S2P) in bacteria.Proc Natl Acad Sci U S A2011
19462754[Molecular mechanisms of SecA-mediated protein translocation viewed from structural studies].Tanpakushitsu Kakusan Koso2009
18923527Conformational transition of Sec machinery inferred from bacterial SecYE structures.Nature2008
16582489Purification, crystallization and preliminary X-ray diffraction of SecDF, a translocon-associated membrane protein, from Thermus thermophilus.Acta Crystallogr Sect F Struct Biol Cryst Commun2006
17005557The long alpha-helix of SecA is important for the ATPase coupling of translocation.J Biol Chem2006
17060619Different modes of SecY-SecA interactions revealed by site-directed in vivo photo-cross-linking.Proc Natl Acad Sci U S A2006
17059823Crystal structure of the translocation ATPase SecA from Thermus thermophilus reveals a parallel, head-to-head dimer.J Mol Biol2006
16946477Cloning, expression, purification, crystallization and initial crystallographic analysis of the preprotein translocation ATPase SecA from Thermus thermophilus.Acta Crystallogr Sect F Struct Biol Cryst Commun2006
15713839SecM facilitates translocase function of SecA by localizing its biosynthesis.Genes Dev2005
15168501[Molecular architecture of protein translocase].Tanpakushitsu Kakusan Koso2004
15175310Mutational analysis of transmembrane regions 3 and 4 of SecY, a central component of protein translocase.J Bacteriol2004
12511485Biochemical characterization of a mutationally altered protein translocase: proton motive force stimulation of the initiation phase of translocation.J Bacteriol2003
14622421Cold shock induction of RNase R and its role in the maturation of the quality control mediator SsrA/tmRNA.Mol Microbiol2003
12655407Interfering mutations provide in vivo evidence that Escherichia coli SecE functions in multimeric states.Mol Genet Genomics2003
12809500Nearest neighbor analysis of the SecYEG complex. 2. Identification of a SecY-SecE cytosolic interface.Biochemistry2003
12809499Nearest neighbor analysis of the SecYEG complex. 1. Identification of a SecY-SecG interface.Biochemistry2003
12756530Importance of transmembrane segments in Escherichia coli SecY.Mol Genet Genomics2003
12533543Fluorescence resonance energy transfer analysis of protein translocase. SecYE from Thermus thermophilus HB8 forms a constitutive oligomer in membranes.J Biol Chem2003
12533470A SecE mutation that modulates SecY-SecE translocase assembly, identified as a specific suppressor of SecY defects.J Bacteriol2003
11914356Roles of the C-terminal end of SecY in protein translocation and viability of Escherichia coli.J Bacteriol2002
12351621Superactive SecY variants that fulfill the essential translocation function with a reduced cellular quantity.J Biol Chem2002
11597451The Sec protein-translocation pathway.Trends Microbiol2001
11309495An essential amino acid residue in the protein translocation channel revealed by targeted random mutagenesis of SecY.Proc Natl Acad Sci U S A2001
11168585Genetic dissection of SecA: suppressor mutations against the secY205 translocase defect.Genes Cells2000
11256624Length recognition at the N-terminal tail for the initiation of FtsH-mediated proteolysis.EMBO Rep2000
10852867A mutation in secY that causes enhanced SecA insertion and impaired late functions in protein translocation.J Bacteriol2000
10982786Two independent mechanisms down-regulate the intrinsic SecA ATPase activity.J Biol Chem2000
10833277Characterization of a mutant form of SecA that alleviates a SecY defect at low temperature and shows a synthetic defect with SecY alteration at high temperature.J Biochem2000
9712851Roles of the periplasmic domain of Escherichia coli FtsH (HflB) in protein interactions and activity modulation.J Biol Chem1998
9644254Amino-terminal region of SecA is involved in the function of SecG for protein translocation into Escherichia coli membrane vesicles.J Biochem1998
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University of California San Francisco
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J. David Gladstone Institutes
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Texas Biomedical Research Institute
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Washington University School of Medicine at St. Louis
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Washington University School of Medicine in St. Louis
Co-authored papers 1