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Author Details
Full Name
Mark J S Kelly
Affiliation
Department of Pharmaceutical Chemistry, University of California San Francisco
ORCID
Career Start Year
2000
Papers
30
H Index
17
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
33621062
Recognition of Histone H3 Methylation States by the PHD1 Domain of Histone Demethylase KDM5A.
ACS Chem Biol
2023
36495919
Chromatin Sensing by the Auxiliary Domains of KDM5C Regulates Its Demethylase Activity and Is Disrupted by X-linked Intellectual Disability Mutations.
J Mol Biol
2023
36166818
Probing the KRas Switch II Groove by Fluorine NMR Spectroscopy.
ACS Chem Biol
2022
34646016
Systems-level effects of allosteric perturbations to a model molecular switch.
Nature
2021
32855341
Expanding the space of protein geometries by computational design of de novo fold families.
Science
2020
30561869
HDAC inhibition in glioblastoma monitored by hyperpolarized <sup>13</sup> C MRSI.
NMR Biomed
2019
31754004
Computational design of a modular protein sense-response system.
Science
2019
31447178
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain.
Cell
2019
29315319
The centrosomin CM2 domain is a multi-functional binding domain with distinct cell cycle roles.
PLoS One
2018
28837163
A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells.
Nat Chem
2017
25686748
Histone demethylase KDM5A is regulated by its reader domain through a positive-feedback mechanism.
Nat Commun
2015
26554011
Allosteric N-WASP activation by an inter-SH3 domain linker in Nck.
Proc Natl Acad Sci U S A
2015
25859978
Biophysical methods for identifying fragment-based inhibitors of protein-protein interactions.
Methods Mol Biol
2015
25690569
A Fragment-Based Ligand Screen Against Part of a Large Protein Machine: The ND1 Domains of the AAA+ ATPase p97/VCP.
J Biomol Screen
2015
24726919
Elucidating the mechanism of substrate recognition by the bacterial Hsp90 molecular chaperone.
J Mol Biol
2014
23159126
Design of a phosphorylatable PDZ domain with peptide-specific affinity changes.
Structure
2013
23748856
13C NMR metabolomic evaluation of immediate and delayed mild hypothermia in cerebrocortical slices after oxygen-glucose deprivation.
Anesthesiology
2013
23708689
1H nuclear magnetic resonance brain metabolomics in neonatal mice after hypoxia-ischemia distinguished normothermic recovery from mild hypothermia recoveries.
Pediatr Res
2013
20717124
Outcome-related metabolomic patterns from 1H/31P NMR after mild hypothermia treatments of oxygen-glucose deprivation in a neonatal brain slice model of asphyxia.
J Cereb Blood Flow Metab
2011
22072900
Metabolomics of oxidative stress in recent studies of endogenous and exogenously administered intermediate metabolites.
Int J Mol Sci
2011
21333653
Radically different amyloid conformations dictate the seeding specificity of a chimeric Sup35 prion.
J Mol Biol
2011
19041675
Antioxidant effect of ethyl pyruvate in respiring neonatal cerebrocortical slices after H(2)O(2) stress.
Neurochem Int
2009
19029335
Cofilin is a pH sensor for actin free barbed end formation: role of phosphoinositide binding.
J Cell Biol
2008
18780792
Structural model and functional significance of pH-dependent talin-actin binding for focal adhesion remodeling.
Proc Natl Acad Sci U S A
2008
16736046
Pyruvate improves recovery after PARP-1-associated energy failure induced by oxidative stress in neonatal rat cerebrocortical slices.
J Cereb Blood Flow Metab
2007
17893460
Exogenous ethyl pyruvate versus pyruvate during metabolic recovery after oxidative stress in neonatal rat cerebrocortical slices.
Anesthesiology
2007
17767153
The structural basis of yeast prion strain variants.
Nature
2007
17337638
Parallel beta-helix proteins required for accurate capsule polysaccharide synthesis and virulence in the yeast Cryptococcus neoformans.
Eukaryot Cell
2007
15377881
Using 31P NMR spectroscopy at 14.1 Tesla to investigate PARP-1 associated energy failure and metabolic rescue in cerebrocortical slices.
J Bioenerg Biomembr
2004
10764585
Similarities between the spectrin SH3 domain denatured state and its folding transition state.
J Mol Biol
2000
1 - 30 of 30
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Co-authored papers
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University of California San Francisco
Co-authored papers
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Brandeis University
Co-authored papers
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