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Author Details

Gudrun G??hring
Hannover Medical School
2002
234
47
PMIDPaper TitleJournal TitlePublished Year
37470150Fludarabine, cytarabine, and idarubicin with or without venetoclax in patients with relapsed/refractory acute myeloid leukemia.Haematologica2024
38086945Panel-based RNA fusion sequencing improves diagnostics of pediatric acute myeloid leukemia.Leukemia2024
37706343Somatic variant profiling in chronic phase pediatric chronic myeloid leukemia.Haematologica2024
37584291Spontaneous remission and loss of monosomy 7: a window of opportunity for young children with SAMD9L syndrome.Haematologica2024
36657267Rare and potentially fatal - Cytogenetically cryptic TNIP1::PDGFRB and PCM1::FGFR1 fusion leading to myeloid/lymphoid neoplasms with eosinophilia in children.Cancer Genet2023
37756525Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy.Blood2023
35484682Molecular characterization and clinical outcome of B-cell precursor acute lymphoblastic leukemia with IG-MYC rearrangement.Haematologica2023
37104932Generation of two human NRF2 knockout iPSC clones using CRISPR/Cas9 editing.Stem Cell Res2023
36775010European standard clinical practice - Key issues for the medical care of individuals with familial leukemia.Eur J Med Genet2023
36463634Generation of human induced pluripotent stem cell line encoding for a genetically encoded voltage indicator Arclight A242.Stem Cell Res2023
36672158iPSC-Derived Striatal Medium Spiny Neurons from Patients with Multiple System Atrophy Show Hypoexcitability and Elevated α-Synuclein Release.Cells2023
36823455Second allogeneic stem cell transplantation can rescue a significant proportion of patients with JMML relapsing after first allograft.Bone Marrow Transplant2023
34839233Classification of fluorescent R-Band metaphase chromosomes using a convolutional neural network is precise and fast in generating karyograms of hematologic neoplastic cells.Cancer Genet2022
35406484The Cytogenetic Landscape of Pediatric Chronic Myeloid Leukemia Diagnosed in Chronic Phase.Cancers (Basel)2022
35795779Targeted biallelic integration of an inducible Caspase 9 suicide gene in iPSCs for safer therapies.Mol Ther Methods Clin Dev2022
35636247Generation of an induced pluripotent stem cell line (DHMCi008-A) from an individual with TUBA1A tubulinopathy.Stem Cell Res2022
35362549Evolution of severe (transfusion-dependent) anaemia in myelodysplastic syndromes with 5q deletion is characterized by a macrophage-associated failure of the eythropoietic niche.Br J Haematol2022
35565187Optical Genome Mapping as a Diagnostic Tool in Pediatric Acute Myeloid Leukemia.Cancers (Basel)2022
35875134Clonal Evolution at First Sight: A Combined Visualization of Diverse Diagnostic Methods Improves Understanding of Leukemic Progression.Front Oncol2022
36307508Wildtype heterogeneity contributes to clonal variability in genome edited cells.Sci Rep2022
35930870Generation of an induced pluripotent stem cell line (DHMCi009-A) from an individual with TUBB2A tubulinopathy.Stem Cell Res2022
36162332Generation of two TMEM16A knockout iPSC clones each from a healthy human iPSC line, from a Cystic Fibrosis patient specific line with p.Phe508del mutation and from the gene corrected iPSC line.Stem Cell Res2022
35152180Generation of human induced pluripotent stem cell lines encoding for genetically encoded calcium indicators RCaMP1h and GCaMP6f.Stem Cell Res2022
35277655"Randomized phase II study of azacitidine ± lenalidomide in higher-risk myelodysplastic syndromes and acute myeloid leukemia with a karyotype including Del(5q)".Leukemia2022
34732858A unique role of p53 haploinsufficiency or loss in the development of acute myeloid leukemia with FLT3-ITD mutation.Leukemia2022
34460133Cryptic TCF3 fusions in childhood leukemia: Detection by RNA sequencing.Genes Chromosomes Cancer2022
32948843IDH1/2 mutations in acute myeloid leukemia patients and risk of coronary artery disease and cardiac dysfunction-a retrospective propensity score analysis.Leukemia2021
33571874Establishment of MHHi001-A-5, a GCaMP6f and RedStar dual reporter human iPSC line for in vitro and in vivo characterization and in situ tracing of iPSC derivatives.Stem Cell Res2021
33875720Severe allo-immune antibody-associated peripheral and central nervous system diseases after allogeneic hematopoietic stem cell transplantation.Sci Rep2021
33486841Unbalanced translocation der(5;17) resulting in a TP53 loss as recurrent aberration in myelodysplastic syndrome and acute myeloid leukemia with complex karyotype.Genes Chromosomes Cancer2021
33647814BCR-ABL1 positive AML or CML in blast crisis? A pediatric case report with inv(3) and t(9;22) in the initial clone.Cancer Genet2021
33725366Impact of PPM1D mutations in patients with myelodysplastic syndrome and deletion of chromosome 5q.Am J Hematol2021
33725366Impact of PPM1D mutations in patients with myelodysplastic syndrome and deletion of chromosome 5q.Am J Hematol2021
33690887Paediatric chronic myeloid leukaemia presenting in de novo or secondary blast phase - a comparison of clinical and genetic characteristics.Br J Haematol2021
33578365Generation of two iPSC clones (MHHi021-A and MHHi021-B) from a patient with hypertrophic cardiomyopathy with p.Arg723Gly mutation in the MYH7 gene.Stem Cell Res2021
34469508Association of unbalanced translocation der(1;7) with germline GATA2 mutations.Blood2021
34695767Generation of an induced pluripotent stem cell line (DHMCi006-A) from a patient with autosomal recessive polycystic kidney disease (ARPKD) carrying a compound heterozygous missense mutation in the fibrocystin encoding PKHD1 gene.Stem Cell Res2021
34782764Chromothripsis followed by circular recombination drives oncogene amplification in human cancer.Nat Genet2021
34688127Generation of an induced pluripotent stem cell line (DHMCi007-A) from a patient with autosomal recessive polycystic kidney disease (ARPKD) carrying a homozygous missense mutation in the fibrocystin-encoding PKHD1 gene.Stem Cell Res2021
34769003Germline POT1 Deregulation Can Predispose to Myeloid Malignancies in Childhood.Int J Mol Sci2021
34560000iPSC culture expansion selects against putatively actionable mutations in the mitochondrial genome.Stem Cell Reports2021
34503197The Clinical Utility of Optical Genome Mapping for the Assessment of Genomic Aberrations in Acute Lymphoblastic Leukemia.Cancers (Basel)2021
34244664Hematopoietic stem cell transplantation in children and adolescents with GATA2-related myelodysplastic syndrome.Bone Marrow Transplant2021
34196171A novel classification of hematologic conditions in patients with Fanconi anemia.Haematologica2021
33197935SSBP2-CSF1R is a recurrent fusion in B-lineage acute lymphoblastic leukemia with diverse genetic presentation and variable outcome.Blood2021
33443157Knockout of the HMG domain of the porcine SRY gene causes sex reversal in gene-edited pigs.Proc Natl Acad Sci U S A2021
32705308Risk of tumor lysis syndrome in patients with acute myeloid leukemia treated with venetoclax-containing regimens without dose ramp-up.Ann Hematol2021
31601692Relapses and treatment-related events contributed equally to poor prognosis in children with ABL-class fusion positive B-cell acute lymphoblastic leukemia treated according to AIEOP-BFM protocols.Haematologica2020
32000109Human STAT1 gain-of-function iPSC line from a patient suffering from chronic mucocutaneous candidiasis.Stem Cell Res2020
31837633Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual.Stem Cell Res2020
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Collaborators

Michael Heuser
Hannover Medical School
Co-authored papers 49
Felicitas Thol
Hannover Medical School
Co-authored papers 45
Doris Steinemann
Hannover Medical School
Co-authored papers 36
Charlotte M Niemeyer
Co-authored papers 27
Michael Dworzak
St. Anna Children's Cancer Research Institute (CCRI)
Co-authored papers 10
Doris Kraemer
Co-authored papers 4
Peter Lichter
German Cancer Research Center (DKFZ)
Co-authored papers 4
Christoph Klein
Kinderklinik und Kinderpoliklinik der Ludwig-Maximilians-Universitat Munchen
Co-authored papers 3
Christian P Kratz
Co-authored papers 3
Simone Feurstein
University Hospital Heidelberg
Co-authored papers 3
Markus Metzler
University Hospital Erlangen
Co-authored papers 3
Manuela Krumbholz
University Hospital Erlangen
Co-authored papers 3
Simon J Boulton
The Francis Crick Institute
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Wolfgang E Berdel
University Hospital Munster
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Torsten Haferlach
Taussig Cancer Institute, Cleveland Clinic
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Christof von Kalle
Berlin Institute of Health at Charite-Universitatsmedizin Berlin
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Hiroko Tanaka
Tokyo Medical and Dental University
Co-authored papers 2
Hartmut Hecker
Hannover Medical School
Co-authored papers 2
Anthony V Moorman
Translational and Clinical Research Institute, Newcastle University
Co-authored papers 2
Arndt Borkhardt
Hematology and Clinical Immunology, Heinrich Heine University Dusseldorf
Co-authored papers 2
Friedrich St??lzel
University Hospital TU Dresden
Co-authored papers 2
Jan O Korbel
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 2
Franz Schaefer
University Children's Hospital Heidelberg
Co-authored papers 2
Beat W Sch??fer
Department of Oncology and Children's Research Center, University Children's Hospital
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Julian Varghese
Hopp Children's Cancer Center (KiTZ)
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Udo Kontny
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Mignon L Loh
University of Washington
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Thomas Klingebiel
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Release 1.2