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Author Details

Christopher L Morton
St. Jude Children's Research Hospital.
1992
113
50
PMIDPaper TitleJournal TitlePublished Year
36993649The Genetic and Epigenetic Features of Bilateral Wilms Tumor Predisposition: A Report from the Children's Oncology Group AREN18B5-Q Study.Res Sq2023
35211640Preventing packaging of translatable P5-associated DNA contaminants in recombinant AAV vector preps.Mol Ther Methods Clin Dev2022
35406427<i>TERT</i> Expression in Wilms Tumor Is Regulated by Promoter Mutation or Hypermethylation, WT1, and N-MYC.Cancers (Basel)2022
35450020Approaches to identifying drug resistance mechanisms to clinically relevant treatments in childhood rhabdomyosarcoma.Cancer Drug Resist2022
31862972Forty-five patient-derived xenografts capture the clinical and biological heterogeneity of Wilms tumor.Nat Commun2019
31693904Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design.Cell Rep2019
29055620Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.Mol Ther2018
28985851In-bag enzymatic splenic digestion: a novel alternative to manual morcellation?J Surg Res2017
27069949Distribution of AAV8 particles in cell lysates and culture media changes with time and is dependent on the recombinant vector.Mol Ther Methods Clin Dev2016
25925418The role of histone demethylase KDM4B in Myc signaling in neuroblastoma.J Natl Cancer Inst2015
26824057Regulated lysosomal exocytosis mediates cancer progression.Sci Adv2015
24038993Initial testing (stage 1) of the histone deacetylase inhibitor, quisinostat (JNJ-26481585), by the Pediatric Preclinical Testing Program.Pediatr Blood Cancer2014
25409372Long-term safety and efficacy of factor IX gene therapy in hemophilia B.N Engl J Med2014
23331791HIF-1α activation mediates resistance to anti-angiogenic therapy in neuroblastoma xenografts.J Pediatr Surg2013
24332040Targeting oxidative stress in embryonal rhabdomyosarcoma.Cancer Cell2013
23408929Curcumin potentiates rhabdomyosarcoma radiosensitivity by suppressing NF-κB activity.PLoS One2013
23406775Establishment and characterization of the first pediatric adrenocortical carcinoma xenograft model identifies topotecan as a potential chemotherapeutic agent.Clin Cancer Res2013
23426947Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant.Blood2013
23335050Initial testing (stage 1) of temozolomide by the pediatric preclinical testing program.Pediatr Blood Cancer2013
21337679Initial testing (stage 1) of the mTOR kinase inhibitor AZD8055 by the pediatric preclinical testing program.Pediatr Blood Cancer2012
22509977Inhibition of type I interferon-mediated antiviral action in human glioma cells by the IKK inhibitors BMS-345541 and TPCA-1.J Interferon Cytokine Res2012
22284765Liposome-encapsulated curcumin suppresses neuroblastoma growth through nuclear factor-kappa B inhibition.Surgery2012
22315240Initial testing (stage 1) of the cyclin dependent kinase inhibitor SCH 727965 (dinaciclib) by the pediatric preclinical testing program.Pediatr Blood Cancer2012
22012946Initial testing of the investigational NEDD8-activating enzyme inhibitor MLN4924 by the pediatric preclinical testing program.Pediatr Blood Cancer2012
22190407Initial testing of the multitargeted kinase inhibitor pazopanib by the Pediatric Preclinical Testing Program.Pediatr Blood Cancer2012
22134170AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage.Blood2012
21922647Initial testing of JNJ-26854165 (Serdemetan) by the pediatric preclinical testing program.Pediatr Blood Cancer2012
21630428Combination testing (Stage 2) of the Anti-IGF-1 receptor antibody IMC-A12 with rapamycin by the pediatric preclinical testing program.Pediatr Blood Cancer2012
21584937Initial testing of the CENP-E inhibitor GSK923295A by the pediatric preclinical testing program.Pediatr Blood Cancer2012
21548007Testing of the topoisomerase 1 inhibitor Genz-644282 by the pediatric preclinical testing program.Pediatr Blood Cancer2012
21538824Combination testing of cediranib (AZD2171) against childhood cancer models by the pediatric preclinical testing program.Pediatr Blood Cancer2012
21538821Initial testing (Stage 1) of AT13387, an HSP90 inhibitor, by the pediatric preclinical testing program.Pediatr Blood Cancer2012
21681929Initial testing (stage 1) of LCL161, a SMAC mimetic, by the Pediatric Preclinical Testing Program.Pediatr Blood Cancer2012
20922763National Cancer Institute pediatric preclinical testing program: model description for in vitro cytotoxicity testing.Pediatr Blood Cancer2011
22149959Adenovirus-associated virus vector-mediated gene transfer in hemophilia B.N Engl J Med2011
21878236Continuous local delivery of interferon-β stabilizes tumor vasculature in an orthotopic glioblastoma xenograft resection model.Surgery2011
21744473Initial testing of the hypoxia-activated prodrug PR-104 by the pediatric preclinical testing program.Pediatr Blood Cancer2011
21298745Initial testing (stage 1) of the IGF-1 receptor inhibitor BMS-754807 by the pediatric preclinical testing program.Pediatr Blood Cancer2011
21360651Initial testing of lenalidomide by the pediatric preclinical testing program.Pediatr Blood Cancer2011
21360650Initial testing (stage 1) of the polyamine analog PG11047 by the pediatric preclinical testing program.Pediatr Blood Cancer2011
21448591Efficacy and pharmacokinetic/pharmacodynamic evaluation of the Aurora kinase A inhibitor MLN8237 against preclinical models of pediatric cancer.Cancer Chemother Pharmacol2011
20017204Initial testing of topotecan by the pediatric preclinical testing program.Pediatr Blood Cancer2010
20806365Initial testing (stage 1) of AZD6244 (ARRY-142886) by the Pediatric Preclinical Testing Program.Pediatr Blood Cancer2010
20740623Initial testing (stage 1) of the Akt inhibitor GSK690693 by the pediatric preclinical testing program.Pediatr Blood Cancer2010
20979180Evaluation of cytarabine against Ewing sarcoma xenografts by the pediatric preclinical testing program.Pediatr Blood Cancer2010
20672370Initial testing (stage 1) of the multi-targeted kinase inhibitor sorafenib by the pediatric preclinical testing program.Pediatr Blood Cancer2010
20582972Initial testing of the replication competent Seneca Valley virus (NTX-010) by the pediatric preclinical testing program.Pediatr Blood Cancer2010
20166202Initial testing of a monoclonal antibody (IMC-A12) against IGF-1R by the Pediatric Preclinical Testing Program.Pediatr Blood Cancer2010
19856388Initial testing (stage 1) of mapatumumab (HGS-ETR1) by the pediatric preclinical testing program.Pediatr Blood Cancer2010
20053767Stage 2 combination testing of rapamycin with cytotoxic agents by the Pediatric Preclinical Testing Program.Mol Cancer Ther2010
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Robert H Shoemaker
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Lee J Helman
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Scott H Kaufmann
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Anne Monks
Institute of Biomedical Engineering (IBME), University of Oxford
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Collaborators

Peter J Houghton
The University of Texas Health Science Center at San Antonio
Co-authored papers 62
Malcolm A Smith
National Cancer Institute
Co-authored papers 49
Charles Patrick Reynolds
Cancer Center, Texas Tech University Health Sciences Center
Co-authored papers 43
John M Maris
Children's Hospital of Philadelphia
Co-authored papers 42
Stephen T Keir
Co-authored papers 42
Richard B Lock
Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine
Co-authored papers 40
Richard Gorlick
University of Texas MD Anderson Cancer Center
Co-authored papers 40
Edward A Kolb
Co-authored papers 40
Raushan T Kurmasheva
The University of Texas Health Science Center at San Antonio
Co-authored papers 8
Matthew R Redinbo
University of North Carolina at Chapel Hill
Co-authored papers 7
Geoffrey Neale
St. Jude Children's Research Hospital
Co-authored papers 6
John Easton
St Jude Children's Research Hospital
Co-authored papers 4
Javed Khan
Center for Cancer Research, National Cancer Institute
Co-authored papers 4
Joel L Sussman
Weizmann Institute of Science
Co-authored papers 3
Jinghui Zhang
Changhai Hospital, Second Military Medical University
Co-authored papers 3
Qing-Rong Chen
Center for Biomedical Informatics and Information Technology
Co-authored papers 2
Xiang Chen
St. Jude Children's Research Hospital
Co-authored papers 2
Henry S Friedman
Co-authored papers 2
Jun S Wei
Center for Cancer Research, National Cancer Institute
Co-authored papers 2
Chunxu Qu
Co-authored papers 2
Ulrike M Reiss
Hospital
Co-authored papers 2
Siyuan Zheng
Greehey Children's Cancer Research Institute
Co-authored papers 2
Wendong Zhang
University of Texas MD Anderson Cancer Center
Co-authored papers 2
Peter Kuhn
University of Tubingen
Co-authored papers 2
Gregory P Way
Broad Institute of MIT and Harvard
Co-authored papers 1
Harshavardhan Doddapaneni
Baylor College of Medicine
Co-authored papers 1
Xiao-Nan Li
Northwestern University
Co-authored papers 1
Chand Khanna
National Cancer Institute, National Institutes of Health
Co-authored papers 1
Holly Lindsay
Texas Children's Cancer Center, Baylor College of Medicine
Co-authored papers 1
Nilsa C Ramirez
Co-authored papers 1
Release 1.2