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Author Details

Yihong Ye
National Institute of Diabetes, National Institutes of Health
1998
108
48
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36848233SAYSD1 senses UFMylated ribosome to safeguard co-translational protein translocation at the endoplasmic reticulum.Cell Rep2023
37759245PI3K-AKT activation resculpts integrin signaling to drive filamentous tau-induced proinflammatory astrogliosis.Cell Biosci2023
37558718Auranofin targets UBA1 and enhances UBA1 activity by facilitating ubiquitin trans-thioesterification to E2 ubiquitin-conjugating enzymes.Nat Commun2023
37674732PI3K-AKT activation resculpts integrin signaling to drive filamentous tau-induced proinflammatory astrogliosis.Res Sq2023
37723160Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation.Nat Commun2023
35506243Abnormal triaging of misfolded proteins by adult neuronal ceroid lipofuscinosis-associated DNAJC5/CSPα mutants causes lipofuscin accumulation.Autophagy2023
37398461HUWE1 Amplifies Ubiquitin Modifications to Broadly Stimulate Clearance of Proteins and Aggregates.bioRxiv2023
37034606Heparan sulfate promotes ACE2 super-cluster assembly to enhance SARS-CoV-2-associated syncytium formation.Res Sq2023
35947953Rhomboid protease RHBDL4 promotes retrotranslocation of aggregation-prone proteins for degradation.Cell Rep2022
35440680Mitoxantrone modulates a heparan sulfate-spike complex to inhibit SARS-CoV-2 infection.Sci Rep2022
35404596Graph Convolutional Network-Based Screening Strategy for Rapid Identification of SARS-CoV-2 Cell-Entry Inhibitors.J Chem Inf Model2022
35790999Advancing equity through strengthening research on health and well-being of Asian American, Native Hawaiian, and Pacific Islander.Cell Biosci2022
35819775Studying Unconventional Secretion of Misfolded Proteins in Cultured Cells and Primary Neurons.Methods Mol Biol2022
35620055Safeguarding Lysosomal Homeostasis by DNAJC5/CSPα-Mediated Unconventional Protein Secretion and Endosomal Microautophagy.Front Cell Dev Biol2022
33351098Chaperoning transmembrane helices in the lipid bilayer.J Cell Biol2021
33490075Clearing Traffic Jams During Protein Translocation Across Membranes.Front Cell Dev Biol2021
34575087Astrocytes in Neurodegenerative Diseases: A Perspective from Tauopathy and α-Synucleinopathy.Life (Basel)2021
33398028Filamentous recombinant human Tau activates primary astrocytes via an integrin receptor complex.Nat Commun2021
31595041UFMylation of RPL26 links translocation-associated quality control to endoplasmic reticulum protein homeostasis.Cell Res2020
33298900Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro.Cell Discov2020
32699847Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs <i>in vitro</i>.bioRxiv2020
32366666A myosin-7B-dependent endocytosis pathway mediates cellular entry of α-synuclein fibrils and polycation-bearing cargos.Proc Natl Acad Sci U S A2020
30830772Discovery of Irreversible p97 Inhibitors.J Med Chem2019
31353312AAGAB Controls AP2 Adaptor Assembly in Clathrin-Mediated Endocytosis.Dev Cell2019
31427794A spiral path to unfolding.Nat Struct Mol Biol2019
31542791Author Correction: AAA ATPASES: A spiral path to unfolding.Nat Struct Mol Biol2019
29531792DNAJC5 facilitates USP19-dependent unconventional secretion of misfolded cytosolic proteins.Cell Discov2018
30072379Secretion of misfolded cytosolic proteins from mammalian cells is independent of chaperone-mediated autophagy.J Biol Chem2018
30167107Proteomic characterization of endogenous substrates of mammalian ubiquitin ligase Hrd1.Cell Biosci2018
30400277The Roles of Endo-Lysosomes in Unconventional Protein Secretion.Cells2018
30444996To Build by Destruction.Mol Cell2018
29549062Regulation of protein homeostasis by unconventional protein secretion in mammalian cells.Semin Cell Dev Biol2018
29430834Nonenzymatic acetylation of ubiquitin Lys side chains is modulated by their neighboring residues.FEBS J2018
28660197A Mighty "Protein Extractor" of the Cell: Structure and Function of the p97/CDC48 ATPase.Front Mol Biosci2017
28165462Ufd2p synthesizes branched ubiquitin chains to promote the degradation of substrates modified with atypical chains.Nat Commun2017
29042515Structural basis for regulation of the nucleo-cytoplasmic distribution of Bag6 by TRC35.Proc Natl Acad Sci U S A2017
29238611Structural basis for nucleotide-modulated p97 association with the ER membrane.Cell Discov2017
28894007RABIF/MSS4 is a Rab-stabilizing holdase chaperone required for GLUT4 exocytosis.Proc Natl Acad Sci U S A2017
28821611The proteasome-interacting Ecm29 protein disassembles the 26S proteasome in response to oxidative stress.J Biol Chem2017
26945625Structure and function of the AAA+ ATPase p97/Cdc48p.Gene2016
27729187Eeyarestatin I derivatives with improved aqueous solubility.Bioorg Med Chem Lett2016
27867533The HECT domain ubiquitin ligase HUWE1 targets unassembled soluble proteins for degradation.Cell Discov2016
27387505Lunapark Is a Component of a Ubiquitin Ligase Complex Localized to the Endoplasmic Reticulum Three-way Junctions.J Biol Chem2016
27295555Unconventional secretion of misfolded proteins promotes adaptation to proteasome dysfunction in mammalian cells.Nat Cell Biol2016
27491350Ever HRD a ubiquitin-gated channel?Cell Res2016
27044894Doa1 is a MAD adaptor for Cdc48.J Cell Biol2016
27103333The Vpu-interacting Protein SGTA Regulates Expression of a Non-glycosylated Tetherin Species.Sci Rep2016
25535373Bag6 complex contains a minimal tail-anchor-targeting module and a mock BAG domain.Proc Natl Acad Sci U S A2015
26424800gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum.Mol Biol Cell2015
26555170In Search of a Cure for Proteostasis-Addicted Cancer: A AAA Target Revealed.Cancer Cell2015
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Collaborators

Yue Xu
South China University of Technology
Co-authored papers 20
Mark E Fortini
Thomas Jefferson University
Co-authored papers 7
Min Shen
National Center for Advancing Translational Sciences, National Institutes of Health
Co-authored papers 3
David Ron
Cambridge Institute for Medical Research, University of Cambridge
Co-authored papers 2
Lan Huang
University of California Irvine
Co-authored papers 2
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Michael Rape
Howard Hughes Medical Institute, University of California at Berkeley
Co-authored papers 1
Xiaorong Wang
University of California Irvine
Co-authored papers 1
Alexander S Huszagh
University of California irvine
Co-authored papers 1
Can Zhang
Co-authored papers 1
Scott D Rychnovsky
University of California irvine
Co-authored papers 1
Sarah A Block
University of California irvine
Co-authored papers 1
Clinton Yu
University of California Irvine
Co-authored papers 1
Peter J Munson
and Blood Institute, National Institutes of Health
Co-authored papers 1
Steven P Gygi
Harvard Medical School
Co-authored papers 1
Yingying Yang
University of California irvine
Co-authored papers 1
Nalini Raghavachari
Division of Geriatrics & Clinical Gerontology, National Institute on Aging
Co-authored papers 1
Xandra O Breakefield
Massachusetts General Hospital
Co-authored papers 1
Ilan E Chemmama
University of California san francisco
Co-authored papers 1
Ted H Hansen
Co-authored papers 1
Peter Cimermancic
Verily Life Sciences LLC
Co-authored papers 1
Ping Xu
Co-authored papers 1
Anton Simeonov
Co-authored papers 1
Rosa Viner
University of California (Davis)
Co-authored papers 1
Release 1.2