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TKG
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Author Details
Full Name
Tariq M Rana
Affiliation
Institute for Genomic Medicine, University of California San Diego
ORCID
Career Start Year
1990
Papers
165
H Index
55
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36689652
PCIF1-mediated deposition of 5'-cap <i>N</i><sup>6</sup>,2'-<i>O</i>-dimethyladenosine in ACE2 and TMPRSS2 mRNA regulates susceptibility to SARS-CoV-2 infection.
Proc Natl Acad Sci U S A
2023
37809493
Generation of 3D lung organoids from human induced pluripotent stem cells for modeling of lung development and viral infection.
Heliyon
2023
35723411
Virologic and Immunologic Characterization of Coronavirus Disease 2019 Recrudescence After Nirmatrelvir/Ritonavir Treatment.
Clin Infect Dis
2023
37022795
Long noncoding RNA HIKER regulates erythropoiesis in Monge's disease via CSNK2B.
J Clin Invest
2023
37040439
1-<i>O</i>-Octadecyl-2-<i>O</i>-benzyl-<i>sn</i>-glyceryl-3-<i>phospho</i>-GS-441524 (V2043). Evaluation of Oral V2043 in a Mouse Model of SARS-CoV-2 Infection and Synthesis and Antiviral Evaluation of Additional Phospholipid Esters with Enhanced Anti-SARS-CoV-2 Activity.
J Med Chem
2023
36968224
Small-molecule PTPN2 Inhibitors Sensitize Resistant Melanoma to Anti-PD-1 Immunotherapy.
Cancer Res Commun
2023
37096144
Neutralizing Antibody Responses After Severe Acute Respiratory Syndrome Coronavirus 2 BA.2 and BA.2.12.1 Infection Do Not Neutralize BA.4 and BA.5 and Can Be Blunted by Nirmatrelvir/Ritonavir Treatment.
Open Forum Infect Dis
2023
36514940
Role of PCIF1-mediated 5'-cap N6-methyladeonsine mRNA methylation in colorectal cancer and anti-PD-1 immunotherapy.
EMBO J
2023
34570513
Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors.
J Med Chem
2022
35547843
Induction of neutralizing antibodies against SARS-CoV-2 variants by a multivalent mRNA-lipid nanoparticle vaccine encoding SARS-CoV-2/SARS-CoV Spike protein receptor-binding domains.
bioRxiv
2022
35713529
Genome-wide CRISPR/Cas9 transcriptional activation screen identifies a histone acetyltransferase inhibitor complex as a regulator of HIV-1 integration.
Nucleic Acids Res
2022
35939803
Rational Design and Optimization of m<sup>6</sup>A-RNA Demethylase FTO Inhibitors as Anticancer Agents.
J Med Chem
2022
35150188
Regulation of antiviral innate immunity by chemical modification of viral RNA.
Wiley Interdiscip Rev RNA
2022
33412003
m<sup>6</sup>A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells.
ACS Chem Biol
2021
33502104
Rapid 3D Bioprinting of Glioblastoma Model Mimicking Native Biophysical Heterogeneity.
Small
2021
33631122
Revealing Tissue-Specific SARS-CoV-2 Infection and Host Responses using Human Stem Cell-Derived Lung and Cerebral Organoids.
Stem Cell Reports
2021
34545078
HIV reprograms host m<sup>6</sup>Am RNA methylome by viral Vpr protein-mediated degradation of PCIF1.
Nat Commun
2021
33961823
METTL3 regulates viral m6A RNA modification and host cell innate immune responses during SARS-CoV-2 infection.
Cell Rep
2021
32051547
Glial cell diversity and methamphetamine-induced neuroinflammation in human cerebral organoids.
Mol Psychiatry
2021
32954948
An atlas of immune cell exhaustion in HIV-infected individuals revealed by single-cell transcriptomics.
Emerg Microbes Infect
2020
31956073
Integrin αvβ5 Internalizes Zika Virus during Neural Stem Cells Infection and Provides a Promising Target for Antiviral Therapy.
Cell Rep
2020
33073500
Zika virus depletes neural stem cells and evades selective autophagy by suppressing the Fanconi anemia protein FANCC.
EMBO Rep
2020
32747553
ALKBH5 regulates anti-PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment.
Proc Natl Acad Sci U S A
2020
32944968
Cholesterol 25-Hydroxylase inhibits SARS-CoV-2 and other coronaviruses by depleting membrane cholesterol.
EMBO J
2020
32964498
m<sup>6</sup> A RNA methyltransferases METTL3/14 regulate immune responses to anti-PD-1 therapy.
EMBO J
2020
30539558
Profiling of N<sup>6</sup>-Methyladenosine in Zika Virus RNA and Host Cellular mRNA.
Methods Mol Biol
2019
31672156
Optimizing sequencing protocols for leaderboard metagenomics by combining long and short reads.
Genome Biol
2019
31216479
Genome-wide Integrative Analysis of Zika-Virus-Infected Neuronal Stem Cells Reveals Roles for MicroRNAs in Cell Cycle and Stemness.
Cell Rep
2019
31551335
The Long Noncoding RNA HEAL Regulates HIV-1 Replication through Epigenetic Regulation of the HIV-1 Promoter.
mBio
2019
31546950
Phytochemicals in <i>Daucus carota</i> and Their Health Benefits-Review Article.
Foods
2019
30808702
HIV-1 Escape from Small-Molecule Antagonism of Vif.
mBio
2019
30918008
The long noncoding RNA <i>ROCKI</i> regulates inflammatory gene expression.
EMBO J
2019
29224076
Next-Generation Sequencing of Genome-Wide CRISPR Screens.
Methods Mol Biol
2018
30427390
Assessment of the yield loss imparted by Orobanche aegyptiaca in tomato in Pakistan.
An Acad Bras Cienc
2018
29615667
Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply.
Nat Commun
2018
28954733
Genome-Wide CRISPR Screen for Essential Cell Growth Mediators in Mutant KRAS Colorectal Cancers.
Cancer Res
2017
28442752
Zika virus infection reprograms global transcription of host cells to allow sustained infection.
Emerg Microbes Infect
2017
25687299
Enhancing Induced Pluripotent Stem Cell Generation by MicroRNA.
Methods Mol Biol
2016
27797851
Identification of novel genes and networks governing hematopoietic stem cell development.
EMBO Rep
2016
27698189
miR-1298 Inhibits Mutant KRAS-Driven Tumor Growth by Repressing FAK and LAMB3.
Cancer Res
2016
27893816
miR-34 Modulates Innate Immunity and Ecdysone Signaling in Drosophila.
PLoS Pathog
2016
27832591
A Herpesvirus Protein Selectively Inhibits Cellular mRNA Nuclear Export.
Cell Host Microbe
2016
27773536
Dynamics of Human and Viral RNA Methylation during Zika Virus Infection.
Cell Host Microbe
2016
27509004
1,2,3-Triazoles as Amide Bioisosteres: Discovery of a New Class of Potent HIV-1 Vif Antagonists.
J Med Chem
2016
27162029
Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3.
Cell Stem Cell
2016
27572442
Dynamics of the human and viral m(6)A RNA methylomes during HIV-1 infection of T cells.
Nat Microbiol
2016
27247273
Polycomb Group Protein Pcgf6 Acts as a Master Regulator to Maintain Embryonic Stem Cell Identity.
Sci Rep
2016
27096704
Synthesis of Eupalinilide E, a Promoter of Human Hematopoietic Stem and Progenitor Cell Expansion.
J Am Chem Soc
2016
26728557
P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates.
Genes Dev
2016
25557168
Therapeutic targeting of polo-like kinase 1 using RNA-interfering nanoparticles (iNOPs) for the treatment of non-small cell lung cancer.
Oncotarget
2015
1 - 50 of 165
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