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Author Details

Michael Xavier Doss
BioMarin Pharmaceutical Inc.
2003
40
19
Kirsten Obernier (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36348622Vector genome loss and epigenetic modifications mediate decline in transgene expression of AAV5 vectors produced in mammalian and insect cells.Mol Ther2022
34831333Application of the Pluripotent Stem Cells and Genomics in Cardiovascular Research-What We Have Learnt and Not Learnt until Now.Cells2021
31052294Current Challenges of iPSC-Based Disease Modeling and Therapeutic Implications.Cells2019
31083689Transcriptional changes associated with advancing stages of heart failure underlie atrial and ventricular arrhythmogenesis.PLoS One2019
29079788Depletion of Mageb16 induces differentiation of pluripotent stem cells predominantly into mesodermal derivatives.Sci Rep2017
28480311STRIP2 Is Indispensable for the Onset of Embryonic Stem Cell Differentiation.Mol Ther Methods Clin Dev2017
29281682Overexpression of Map3k7 activates sinoatrial node-like differentiation in mouse ES-derived cardiomyocytes.PLoS One2017
25591772Electrophysiological characteristics of embryonic stem cell-derived cardiomyocytes are cell line-dependent.Cell Physiol Biochem2015
26473594Differences in the Early Development of Human and Mouse Embryonic Stem Cells.PLoS One2015
24464846A temporal window of vulnerability for development of atrial fibrillation with advancing heart failure.Eur J Heart Fail2014
25010986Fam40b is required for lineage commitment of murine embryonic stem cells.Cell Death Dis2014
24770696Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells.Nat Commun2014
24723659Unique metabolic features of stem cells, cardiomyocytes, and their progenitors.Circ Res2014
23542310Identification and characterization of a transient outward K+ current in human induced pluripotent stem cell-derived cardiomyocytes.J Mol Cell Cardiol2013
21617963Identification of specific pluripotent stem cell death--inducing small molecules by chemical screening.Stem Cell Rev Rep2012
22815737Maximum diastolic potential of human induced pluripotent stem cell-derived cardiomyocytes depends critically on I(Kr).PLoS One2012
22420508Gene expression signatures defining fundamental biological processes in pluripotent, early, and late differentiated embryonic stem cells.Stem Cells Dev2012
21519850Specific gene signatures and pathways in mesodermal cells and their derivatives derived from embryonic stem cells.Stem Cell Rev Rep2012
20088756Induced pluripotent stem cells as a model for accelerated patient- and disease-specific drug discovery.Curr Med Chem2010
24693063Isolation and functional characterization of alpha-smooth muscle actin expressing cardiomyocytes from embryonic stem cells.J Stem Cells Regen Med2010
20711519A comparative analysis of extra-embryonic endoderm cell lines.PLoS One2010
20975998eXtraembryonic ENdoderm (XEN) stem cells produce factors that activate heart formation.PLoS One2010
20511704Isolation and functional characterization of alpha-smooth muscle actin expressing cardiomyocytes from embryonic stem cells.Cell Physiol Biochem2010
20184659Global transcriptomic analysis of murine embryonic stem cell-derived brachyury(+) (T) cells.Genes Cells2010
19203379Three LIF-dependent signatures and gene clusters with atypical expression profiles, identified by transcriptome studies in mouse ES cells and early derivatives.BMC Genomics2009
19727443The FunGenES database: a genomics resource for mouse embryonic stem cell differentiation.PLoS One2009
19345177A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.Cell Stem Cell2009
19064816Functional characterization and transcriptome analysis of embryonic stem cell-derived contractile smooth muscle cells.Hypertension2009
18772879Generation of a double-fluorescent double-selectable Cre/loxP indicator vector for monitoring of intracellular recombination events.Nat Protoc2008
19088448Entrapment of embryonic stem cells-derived cardiomyocytes in macroporous biodegradable microspheres: preparation and characterization.Cell Physiol Biochem2008
19112880Human ES cell derived cardiomyocytes for cell replacement therapy: a current update.Chin J Physiol2008
17428332Global transcriptome analysis of murine embryonic stem cell-derived cardiomyocytes.Genome Biol2007
24692927Global transcriptomic analysis of murine embryonic stem cell-derived cardiomyocytes.J Stem Cells Regen Med2007
17784959Transcriptomic and phenotypic analysis of murine embryonic stem cell derived BMP2+ lineage cells: an insight into mesodermal patterning.Genome Biol2007
16846026Generation and characterization of cardiomyocytes under serum-free conditions.Methods Mol Biol2006
16787199Dietary small molecules and large-scale gene expression studies: an experimental approach for understanding their beneficial effects on the development of malignant and non-malignant proliferative diseases.Curr Med Chem2006
15866224Trapping of growth factors by catechins: a possible therapeutical target for prevention of proliferative diseases.J Nutr Biochem2005
16270623An optimized embryonic stem cell model for consistent gene expression and developmental studies: a fundamental study.Thromb Haemost2005
15601575Embryonic stem cells: a promising tool for cell replacement therapy.J Cell Mol Med2004
14765621Distribution of C282Y and H63D mutations in the HFE gene in healthy Asian Indians and patients with thalassaemia major.Natl Med J India2003
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Collaborators

Institute of Neurophysiology, University of Cologne
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Institute of Neurophysiology, University of Cologne
Co-authored papers 26
Medical University of Vienna
Co-authored papers 13
Clinic for Plastic, Otto von Guericke University
Co-authored papers 11
University Clinics of Cologne
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Max Delbruck Center for Molecular Medicine in the Helmholtz Association (MDC)
Co-authored papers 7
Institute of Neurophysiology
Co-authored papers 6
Research Centre, Ananda College
Co-authored papers 6
Tongji Medical College
Co-authored papers 4
Institute of Computer Science, University of Tartu
Co-authored papers 4
Institute of Neurophysiology, University of Cologne
Co-authored papers 4
University Hospital Carl Gustav Carus, Technische Universitat (TU) Dresden
Co-authored papers 3
Medical Faculty and University Hospital Carl Gustav Carus
Co-authored papers 2
Center for Molecular and Cellular Bioengineering, Technische Universitat Dresden
Co-authored papers 2
Spanish National Cancer Research Centre-CNIO
Co-authored papers 1
McDermott Center for Human Growth and Development.
Co-authored papers 1
Institute of Regeneration and Repair, The University of Edinburgh
Co-authored papers 1
Fort Valley State University
Co-authored papers 1
Faculty of Medicine and University Hospital Carl Gustav Carus
Co-authored papers 1
University of California San Francisco
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Max Planck Institute of Molecular Cell Biology and Genetics
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Max Planck Institute of Molecular Cell Biology and Genetics
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Ontario Institute for Cancer Research
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Medical Faculty and University Hospital Carl Gustav Carus
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