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Author Details

Jung-Bum Shin
University of Virginia
2002
31
22
PMIDPaper TitleJournal TitlePublished Year
37294664Repair of noise-induced damage to stereocilia F-actin cores is facilitated by XIRP2 and its novel mechanosensor domain.Elife2023
37982489Differential regulation of hair cell actin cytoskeleton mediated by SRF and MRTFB.Elife2023
35597802Stress-induced despair behavior develops independently of the Ahr-RORγt axis in CD4⿿+⿿cells.Sci Rep2022
34050020A nonsense <i>TMEM43</i> variant leads to disruption of connexin-linked function and autosomal dominant auditory neuropathy spectrum disorder.Proc Natl Acad Sci U S A2021
33762902Adrenergic Mechanisms of Audiogenic Seizure-Induced Death in a Mouse Model of <i>SCN8A</i> Encephalopathy.Front Neurosci2021
34348092Cryptosporidium rhoptry effector protein ROP1 injected during invasion targets the host cytoskeletal modulator LMO7.Cell Host Microbe2021
32350269Myosin-VIIa is expressed in multiple isoforms and essential for tensioning the hair cell mechanotransduction complex.Nat Commun2020
30992136Mechanisms of Hair Cell Damage and Repair.Trends Neurosci2019
30733218Necroptosis and Apoptosis Contribute to Cisplatin and Aminoglycoside Ototoxicity.J Neurosci2019
30850599LMO7 deficiency reveals the significance of the cuticular plate for hearing function.Nat Commun2019
29033791Protein Synthesis Inhibition and Activation of the c-Jun N-Terminal Kinase Are Potential Contributors to Cisplatin Ototoxicity.Front Cell Neurosci2017
25653358A short splice form of Xin-actin binding repeat containing 2 (XIRP2) lacking the Xin repeats is required for maintenance of stereocilia morphology and hearing function.J Neurosci2015
26645194Hair-bundle proteomes of avian and mammalian inner-ear utricles.Sci Data2015
24319057Correlation of actin crosslinker and capper expression levels with stereocilia growth phases.Mol Cell Proteomics2014
24845721A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear.Nat Commun2014
24295401Accurate label-free protein quantitation with high- and low-resolution mass spectrometers.J Proteome Res2014
23334578Molecular architecture of the chick vestibular hair bundle.Nat Neurosci2013
23407963A novel role of cytosolic protein synthesis inhibition in aminoglycoside ototoxicity.J Neurosci2013
22307652Distinct energy metabolism of auditory and vestibular sensory epithelia revealed by quantitative mass spectrometry using MS2 intensity.Proc Natl Acad Sci U S A2012
23055499Localization of PDZD7 to the stereocilia ankle-link associates this scaffolding protein with the Usher syndrome protein network.J Neurosci2012
22457506Large membrane domains in hair bundles specify spatially constricted radixin activation.J Neurosci2012
20660251The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice.J Neurosci2010
18839351Twist-off purification of hair bundles.Methods Mol Biol2009
19321743Unraveling cadherin 23's role in development and mechanotransduction.Proc Natl Acad Sci U S A2009
17270734Hair bundles are specialized for ATP delivery via creatine kinase.Neuron2007
16481439Physical and functional interaction between protocadherin 15 and myosin VIIa in mechanosensory hair cells.J Neurosci2006
17021174The chloride intracellular channel protein CLIC5 is expressed at high levels in hair cell stereocilia and is essential for normal inner ear function.J Neurosci2006
15708491The sensory mechanotransduction ion channel ASIC2 (acid sensitive ion channel 2) is regulated by neurotrophin availability.Neuroscience2005
16116094Xenopus TRPN1 (NOMPC) localizes to microtubule-based cilia in epithelial cells, including inner-ear hair cells.Proc Natl Acad Sci U S A2005
12808460A T-type calcium channel required for normal function of a mammalian mechanoreceptor.Nat Neurosci2003
12194821Neurotrophin-4: a survival factor for adult sensory neurons.Curr Biol2002
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Collaborators

Peter G Gillespie
Oregon Hearing Research Center & Vollum Institute, Oregon Health & Science University
Co-authored papers 15
Larry L David
Oregon Health and Science University
Co-authored papers 6
Phillip A Wilmarth
Oregon Health & Science University
Co-authored papers 6
James M Pagana
Co-authored papers 5
Dongseok Choi
Oregon Health & Science University School of Medicine
Co-authored papers 5
Kateri J Spinelli
Center for Cardiovascular Analytics, Providence Heart Institute
Co-authored papers 4
Jocelyn F Krey
Oregon Hearing Research Center & Vollum Institute, Oregon Health & Science University
Co-authored papers 4
Nicholas E Sherman
University of Virginia
Co-authored papers 3
Erin D Jeffery
Agenus Inc, American Society for Mass Spectrometry, Hartwick College, Human Proteome Organisation, Large Scale Biology Corp, University of Virginia
Co-authored papers 2
John Klimek
Oregon Health & Science University
Co-authored papers 2
Hongyu Zhao
Oregon Hearing Research Center & Vollum Institute, Oregon Health & Science University
Co-authored papers 2
Andrew N Tauscher
Co-authored papers 1
Cheryl L Stucky
Co-authored papers 1
Nayoung K D Kim
Samsung Genome Institute, Samsung Medical Center
Co-authored papers 1
Debra McMillen
Institute of Molecular Biology, University of Oregon
Co-authored papers 1
Stefan Gr??nder
Institute of Physiology, RWTH Aachen University
Co-authored papers 1
Zoltan Metlagel
Lawrence Berkeley National Laboratory, University of California
Co-authored papers 1
Manfred Auer
Southeast University
Co-authored papers 1
Ahmed Hassan
The University of Texas at Austin
Co-authored papers 1
Woong-Yang Park
Samsung Genome Institute, Samsung Medical Center
Co-authored papers 1
Cory Bystrom
Cedars-Sinai Medical Center
Co-authored papers 1
Release 1.2