Author details

Full Name

Bo Isomaa

Affiliation

ORCID

Career Start Year

1974

Papers

158

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
34951657	A multigenerational study on phenotypic consequences of the most common causal variant of HNF1A-MODY.	Diabetologia	2022
35238956	Correction to: A multigenerational study on phenotypic consequences of the most common causal variant of HNF1A-MODY.	Diabetologia	2022
33219117	Low-cost exercise interventions improve long-term cardiometabolic health independently of a family history of type 2 diabetes: a randomized parallel group trial.	BMJ Open Diabetes Research and Care	2020
30592226	The associations of daylight and melatonin receptor 1B gene rs10830963 variant with glycemic traits: the prospective PPP-Botnia study.		2019
29360107	Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.	Sci Data	2018
30089436	Melatonin receptor 1B gene rs10830963 polymorphism, depressive symptoms and glycaemic traits.		2018
29186428	Genome-wide meta-analysis identifies novel determinants of circulating serum progranulin.	Hum Mol Genet	2018
29371336	HAPT2D: high accuracy of prediction of T2D with a model combining basic and advanced data depending on availability.	European Journal of Endocrinology	2018
29632382	Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.	Nat Genet	2018
29257133	Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.	Sci Data	2017
28341696	A Low-Frequency Inactivating <i>AKT2</i> Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.	Diabetes	2017
28566273	An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.	Diabetes	2017
27398621	The genetic architecture of type 2 diabetes.	Nature	2016
27185156	Increased Melatonin Signaling Is a Risk Factor for Type 2 Diabetes.		2016
27319085	[Update on Current Care Guideline. Diabetes].	Duodecim; laaketieteellinen aikakauskirja	2016
25292440	Modelling of OGTT curve identifies 1 h plasma glucose level as a strong predictor of incident type 2 diabetes: results from two prospective cohorts.	Diabetologia	2015
25625282	Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.	PLoS Genet	2015
24509480	Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.	Nat Genet	2014
25521368	Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin.	PLoS Genet	2014
24813456	Sleep duration and insulin resistance in individuals without type 2 diabetes: the PPP-Botnia study.		2014
24584071	Loss-of-function mutations in SLC30A8 protect against type 2 diabetes.	Nat Genet	2014
24699409	A central role for GRB10 in regulation of islet function in man.	PLoS Genet	2014
23583979	Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.	Nat Genet	2013
23824655	The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis.	PLoS Med	2013
23157220	Family history of Type 1 diabetes affects insulin secretion in patients with 'Type 2' diabetes.	Diabetic Medicine	2013
23111731	Common variant in the HMGA2 gene increases susceptibility to nephropathy in patients with type 2 diabetes.	Diabetologia	2013
23229155	The human L-type calcium channel Cav1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes.	Diabetologia	2013
23557703	Effects of common genetic variants associated with type 2 diabetes and glycemic traits on Î±- and Î²-cell function and insulin action in humans.		2013
23349498	Link between GIP and osteopontin in adipose tissue and insulin resistance.		2013
22238593	A genome-wide association search for type 2 diabetes genes in African Americans.	PLoS One	2012
22511809	Association of variants in HLA-DQA1-DQB1, PTPN22, INS, and CTLA4 with GAD autoantibodies and insulin secretion in nondiabetic adults of the Botnia Prospective Study.	European Journal of Endocrinology	2012
22479202	Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.	PLoS Genet	2012
22747879	Telomere length in blood and skeletal muscle in relation to measures of glycaemia and insulinaemia.	Diabetic Medicine	2012
22885922	Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.	Nat Genet	2012
22837368	Subjective sleep complaints are associated with insulin resistance in individuals without diabetes: the PPP-Botnia Study.	Diabetes Care	2012
22415877	No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels.	Diabetes	2012
23011353	Effect of a common variant of the PCSK2 gene on reduced insulin secretion.	Diabetologia	2012
21254903	Association between depressive symptoms and metabolic syndrome is not explained by antidepressant medication: results from the PPP-Botnia Study.		2012
21922321	A common variant upstream of the PAX6 gene influences islet function in man.	Diabetologia	2012
22189267	Codon 72 polymorphism (rs1042522) of TP53 is associated with changes in diastolic blood pressure over time.	European Journal of Human Genetics	2012
21814873	A large multi-centre European study validates high-sensitivity C-reactive protein (hsCRP) as a clinical biomarker for the diagnosis of diabetes subtypes.	Diabetologia	2011
21308769	Power in the phenotypic extremes: a simulation study of power in discovery and replication of rare variants.	Genet Epidemiol	2011
20846890	A common variant near the PRL gene is associated with increased adiposity in males.	Molecular Genetics and Metabolism	2011
21325017	Two common genetic variants near nuclear-encoded OXPHOS genes are associated with insulin secretion in vivo.	Eur J Endocrinol	2011
21810601	Pleiotropic effects of GIP on islet function involve osteopontin.	Diabetes	2011
21570145	Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies.	Diabetes Res Clin Pract	2011
21953801	Depressive symptoms, antidepressant medication use, and insulin resistance: the PPP-Botnia Study.	Diabetes Care	2011
21706003	Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.	Nat Genet	2011
21873549	Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes.	Diabetes	2011
21826484	Heritability and familiality of type 2 diabetes and related quantitative traits in the Botnia Study.	Diabetologia	2011