Author details

Full Name

Ihor R Lemischka

Affiliation

ORCID

Career Start Year

1981

Papers

132

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37267919	Retraction Notice to: shRNA Knockdown of Bmi-1 Reveals a Critical Role for p21-Rb Pathway in NSC Self-Renewal during Development.		2023
36206733	Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity.	Cell Stem Cell	2022
35652095	Esrrb Regulates Specific Feed-Forward Loops to Transit From Pluripotency Into Early Stages of Differentiation.	Frontiers in Cell and Developmental Biology	2022
33816475	An Esrrb and Nanog Cell Fate Regulatory Module Controlled by Feed Forward Loop Interactions.	Front Cell Dev Biol	2021
33519915	LncRNA H19 Suppresses Osteosarcomagenesis by Regulating snoRNAs and DNA Repair Protein Complexes.	Frontiers in Genetics	2020
31390555	Genomic Integrity Safeguards Self-Renewal in Embryonic Stem Cells.	Cell Rep	2019
31557312	Induction of human hemogenesis in adult fibroblasts by defined factors and hematopoietic coculture.	FEBS Lett	2019
29727814	Feedback control of pluripotency in embryonic stem cells: Signaling, transcription and epigenetics.	Stem Cell Research	2018
30385632	Oncogenic role of SFRP2 in p53-mutant osteosarcoma development via autocrine and paracrine mechanism.	Proc Natl Acad Sci U S A	2018
30289930	Design and validation of an open-source modular Microplate Photoirradiation System for high-throughput photobiology experiments.	PLoS ONE	2018
30517869	Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming.	Cell Rep	2018
28017796	Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity.	Cell Stem Cell	2017
28648899	Transient HES5 Activity Instructs Mesodermal Cells toward a Cardiac Fate.	Stem Cell Reports	2017
27722205	Modeling Cancer with Pluripotent Stem Cells.	Trends in Cancer	2016
26748878	Converting cell fates: generating hematopoietic stem cells de novo via transcription factor reprogramming.	Annals of the New York Academy of Sciences	2016
26970649	Emerging Modeling Concepts and Solutions in Stem Cell Research.	Current Topics in Developmental Biology	2016
27230261	A dual molecular analogue tuner for dissecting protein function in mammalian cells.	Nat Commun	2016
26954547	Hematopoietic Reprogramming In Vitro Informs In Vivo Identification of Hemogenic Precursors to Definitive Hematopoietic Stem Cells.	Developmental Cell	2016
27365423	Identification of factors promoting ex vivo maintenance of mouse hematopoietic stem cells by long-term single-cell quantification.	Blood	2016
26526106	Making a Hematopoietic Stem Cell.	Trends in Cell Biology	2016
28060340	Reprogramming Mouse Embryonic Fibroblasts with Transcription Factors to Induce a Hemogenic Program.	Journal of Visualized Experiments	2016
26198214	Distribution Analyzer, a methodology for identifying and clustering outlier conditions from single-cell distributions, and its application to a Nanog reporter RNAi screen.	BMC Bioinformatics	2015
28725462	A differential network analysis approach for lineage specifier prediction in stem cell subpopulations.	npj Systems Biology and Applications	2015
25860607	Modeling familial cancer with induced pluripotent stem cells.	Cell	2015
25936917	Tex10 Coordinates Epigenetic Control of Super-Enhancer Activity in Pluripotency and Reprogramming.		2015
25637559	NetExplore: a web server for modeling small network motifs.		2015
26095607	Tbx3 Controls Dppa3 Levels and Exit from Pluripotency toward Mesoderm.	Stem Cell Reports	2015
26267829	Single-Cell Analyses of ESCs Reveal Alternative Pluripotent Cell States and Molecular Mechanisms that Control Self-Renewal.	Stem Cell Reports	2015
26456833	Myeloid Dysregulation in a Human Induced Pluripotent Stem Cell Model of PTPN11-Associated Juvenile Myelomonocytic Leukemia.	Cell Rep	2015
25240402	A genome-wide RNAi screen identifies opposing functions of Snai1 and Snai2 on the Nanog dependency in reprogramming.	Molecular Cell	2014
24022884	Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm.	Stem Cells	2014
24335410	There will be blood from fibroblasts.	Cell Cycle	2014
24907133	'From blood to blood': de-differentiation of hematopoietic progenitors to stem cells.	EMBO Journal	2014
25075441	Genomic editing tools to model human diseases with isogenic pluripotent stem cells.		2014
25122140	Construction and validation of a regulatory network for pluripotency and self-renewal of mouse embryonic stem cells.	PLoS Comput Biol	2014
23324626	SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal.	Epigenetics	2013
23911316	Statistical mechanics of pluripotency.	Cell	2013
23770078	Induction of a hemogenic program in mouse fibroblasts.	Cell Stem Cell	2013
23843329	Patterning pluripotency in embryonic stem cells.	Stem Cells	2013
23794736	ESCAPE: database for integrating high-content published data collected from human and mouse embryonic stem cells.	Database (Oxford)	2013
24054986	Epigenetic roles of MLL oncoproteins are dependent on NF-ÎºB.	Cancer Cell	2013
23463008	MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency.	Nat Commun	2013
22264792	KrasG12D-induced IKK2/Î²/NF-ÎºB activation by IL-1Î± and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma.	Cancer Cell	2012
22441292	Combining competition assays with genetic complementation strategies to dissect mouse embryonic stem cell self-renewal and pluripotency.		2012
22901251	Reprogramming cell fates: insights from combinatorial approaches.	Annals of the New York Academy of Sciences	2012
22862944	Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling.	Cell Stem Cell	2012
22988117	Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming.	Proceedings of the National Academy of Sciences of the United States of America	2012
23103910	Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity.	Nat Cell Biol	2012
21652676	Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic stem cells.	Blood	2011
21477851	Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network.	Cell	2011