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Author Details

Peter McGuffin
1976
531
97
PMIDPaper TitleJournal TitlePublished Year
34763734Dimensions of temperament and character as predictors of antidepressant discontinuation, response and adverse reactions during treatment with nortriptyline and escitalopram.Psychol Med2023
37777856GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.Am J Psychiatry2023
33783297Genome-wide association study of suicidal behaviour severity in mood disorders.World J Biol Psychiatry2021
32064741Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.Addict Biol2021
34002096Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.Nat Genet2021
33674754Correction: Investigating rare pathogenic/likely pathogenic exonic variation in bipolar disorder.Mol Psychiatry2021
31318184Trajectories of Suicidal Ideation During 12 Weeks of Escitalopram or Nortriptyline Antidepressant Treatment Among 811 Patients With Major Depressive Disorder.J Clin Psychiatry2019
30445390Family functioning, trauma exposure and PTSD: A cross sectional study.Journal of Affective Disorders2019
30698114Effect of antidepressant switching between nortriptyline and escitalopram after a failed first antidepressant treatment among patients with major depressive disorder.Br J Psychiatry2019
31164008GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.Am J Psychiatry2019
31003785Genome-wide Burden of Rare Short Deletions Is Enriched in Major Depressive Disorder in Four Cohorts.Biol Psychiatry2019
29160301New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation.Pharmacogenomics J2018
28867280Interaction between childhood maltreatment on immunogenetic risk in depression: Discovery and replication in clinical case-control samples.Brain Behav Immun2018
29032294One year double blind study of high vs low frequency subcallosal cingulate stimulation for depression.Journal of Psychiatric Research2018
30104601Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP).Transl Psychiatry2018
30135031Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies.Eur Neuropsychopharmacol2018
30130674Genetic disposition to inflammation and response to antidepressants in major depressive disorder.J Psychiatr Res2018
30080747Unravelling the GSK3β-related genotypic interaction network influencing hippocampal volume in recurrent major depressive disorder.Psychiatr Genet2018
29615645Antidepressant drug-specific prediction of depression treatment outcomes from genetic and clinical variables.Sci Rep2018
29700475Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.Nat Genet2018
28159590Pharmacogenetics of antidepressant response: A polygenic approach.Prog Neuropsychopharmacol Biol Psychiatry2017
28350396Genetic effects influencing risk for major depressive disorder in China and Europe.Transl Psychiatry2017
28642257Interaction between the <i>FTO</i> gene, body mass index and depression: meta-analysis of 13701 individuals.Br J Psychiatry2017
28977440Advancing psychiatric genetics through dissecting heterogeneity.Human Molecular Genetics2017
28879470Childhood maltreatment and the medical morbidity in bipolar disorder: a case-control study.International Journal of Bipolar Disorders2017
28478783Genetic and other risk factors for suicidal ideation and the relationship with depression.Psychological Medicine2017
28285246The DAOA gene is associated with schizophrenia in the Taiwanese population.Psychiatry Research2017
28257825Association between C-reactive protein (CRP) with depression symptom severity and specific depressive symptoms in major depression.Brain Behav Immun2017
27696737Highly polygenic architecture of antidepressant treatment response: Comparative analysis of SSRI and NRI treatment in an animal model of depression.Am J Med Genet B Neuropsychiatr Genet2017
28218048An Erudite Encounter with: Peter McGuffin CBE.Australian and New Zealand Journal of Psychiatry2017
28102561Stressful life events and catechol-O-methyl-transferase (COMT) gene in bipolar disorder.Depression and Anxiety2017
26621261Transcriptomics and the mechanisms of antidepressant efficacy.Eur Neuropsychopharmacol2016
25861698Phenotypic Association Analyses With Copy Number Variation in Recurrent Depressive Disorder.Biol Psychiatry2016
27151072Immune signatures and disorder-specific patterns in a cross-disorder gene expression analysis.Br J Psychiatry2016
26974950Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders.Nat Neurosci2016
26752265Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma.Nat Genet2016
27089522Combining clinical variables to optimize prediction of antidepressant treatment outcomes.J Psychiatr Res2016
27406289Machine learning, statistical learning and the future of biological research in psychiatry.Psychological Medicine2016
26989099Evaluation of the validity and utility of a transdiagnostic psychosis dimension encompassing schizophrenia and bipolar disorder.British Journal of Psychiatry2016
26526099Polygenic interactions with environmental adversity in the aetiology of major depressive disorder.Psychol Med2016
26440730Analysis of the effects of depression associated polymorphisms on the activity of the BICC1 promoter in amygdala neurones.Pharmacogenomics Journal2016
25108803DNA modification study of major depressive disorder: beyond locus-by-locus comparisons.Biol Psychiatry2015
25917933A genome-wide association study of suicide severity scores in bipolar disorder.J Psychiatr Res2015
25745134Modulatory effects of brain-derived neurotrophic factor Val66Met polymorphism on prefrontal regions in major depressive disorder.Br J Psychiatry2015
25698070Familiality and SNP heritability of age at onset and episodicity in major depressive disorder.Psychol Med2015
25656077The relationship between schizophrenia and rheumatoid arthritis revisited: genetic and epidemiological analyses.Am J Med Genet B Neuropsychiatr Genet2015
25903154A genetic risk score combining 32 SNPs is associated with body mass index and improves obesity prediction in people with major depressive disorder.BMC Med2015
25761838Exploring the role of drug-metabolising enzymes in antidepressant side effects.Psychopharmacology (Berl)2015
26429689Authors' reply.British Journal of Psychiatry2015
26302953The successful search for genetic loci associated with depression.Genome Medicine2015
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Co-authored papers 194
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Central Institute of Mental Health, University of Mannheim
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University Hospital Bonn
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Institute of Psychiatry, King's College London
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Poznan University of Medical Sciences
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the University of Hong Kong
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Institute of Psychiatry, King's College London
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Washington University School of Medicine
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Max Planck Institute of Psychiatry
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Institute of Medical Sciences, University of Toronto
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Institute of Human Genetics, University Hospital Bonn
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Center for Quantitative Health, Massachusetts General Hospital
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Brigham and Women's Hospital
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