Author details

Full Name

Philipp Mertins

Affiliation

ORCID

Career Start Year

2006

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37842925	Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators.	Cardiovasc Res	2024
36918223	Response to: Correspondence on 'H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2+ patients with diffuse midline glioma' by Chheda .		2023
35917568	SUMOylation inhibition overcomes proteasome inhibitor resistance in multiple myeloma.	Blood advances	2023
37648814	Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.	Leukemia	2023
37414422	Longitudinal effects of elexacaftor/tezacaftor/ivacaftor on sputum viscoelastic properties, airway infection and inflammation in patients with cystic fibrosis.		2023
37402719	Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN.	Nat Commun	2023
36646877	Massively parallel identification of mRNA localization elements in primary cortical neurons.	Nat Neurosci	2023
36890585	NeurofibromatosisÂ type 1-dependent alterations in mouse microglia function are not cell-intrinsic.		2023
36806354	Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames.	Mol Cell	2023
36627164	Disease- and sex-specific differences in patients with heart valve disease: a proteome study.		2023
37001827	Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder.		2023
37365888	Carm1-arginine methylation of the transcription factor C/EBPÎ± regulates transdifferentiation velocity.		2023
35197447	Proteomic profiling reveals CDK6 upregulation as a targetable resistance mechanism for lenalidomide in multiple myeloma.	Nature Communications	2022
35652819	The SCF/KIT axis in human mast cells: Capicua acts as potent KIT repressor and ERK predominates PI3K.	Allergy	2022
36302767	Epithelial coxsackievirus adenovirus receptor promotes house dust mite-induced lung inflammation.	Nature Communications	2022
36302563	H3.3K27M mutation is not a suitable target for immunotherapy in HLA-A2 patients with diffuse midline glioma.	Journal for ImmunoTherapy of Cancer	2022
36351382	Pan-claudin family interactome analysis reveals shared and specific interactions.	Cell Reports	2022
35879366	Therapeutic targeting of ATR in alveolar rhabdomyosarcoma.	Nature Communications	2022
35563440	The Anti-Glucocorticoid Receptor Antibody Clone 5E4: Raising Awareness of Unspecific Antibody Binding.	International Journal of Molecular Sciences	2022
36206048	Serum dihydrotestosterone levels are associated with adverse myocardial remodeling in patients with severe aortic valve stenosis before and after aortic valve replacement.	American Journal of Physiology - Heart and Circulatory Physiology	2022
36125911	Protective Î±1-antitrypsin effects in autoimmune vasculitis are compromised by methionine oxidation.	Journal of Clinical Investigation	2022
36122410	Immune Phenotypes and Target Antigens of Clonally Expanded Bone Marrow T Cells in Treatment-NaÃ¯ve Multiple Myeloma.	Cancer Immunology Research	2022
36443295	DNA methylation-based classification of sinonasal tumors.	Nat Commun	2022
36685499	A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation.		2022
35297663	Robust co-immunoprecipitation with mass spectrometry for using solid-phase enhanced sample preparation.	BioTechniques	2022
35296430	Metabolic reprogramming of synovial fibroblasts in osteoarthritis by inhibition of pathologically overexpressed pyruvate dehydrogenase kinases.	Metabolic Engineering	2022
35173582	Uncoupling the Excitatory Amino Acid Transporter 2 From Its C-Terminal Interactome Restores Synaptic Glutamate Clearance at Corticostriatal Synapses and Alleviates Mutant Huntingtin-Induced Hypokinesia.	Front Cell Neurosci	2022
35155612	Paracrine Interleukin 6 Induces Cerebral Remodeling at Early Stages After Unilateral Common Carotid Artery Occlusion in Mice.	Frontiers in Cardiovascular Medicine	2021
34117251	Comprehensive micro-scaled proteome and phosphoproteome characterization of archived retrospective cancer repositories.	Nat Commun	2021
34159634	Surface AMP deaminase 2 as a novel regulator modifying extracellular adenine nucleotide metabolism.	FASEB Journal	2021
33574090	YAP and Î²-Catenin Cooperate to Drive Oncogenesis in Basal Breast Cancer.	Cancer Research	2021
34247190	The newly identified MEK1 tyrosine phosphorylation target MACC1 is druggable by approved MEK1 inhibitors to restrict colorectal cancer metastasis.	Oncogene	2021
34189442	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPÎ±.	iScience	2021
33212364	Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine.	Neoplasia	2021
34403366	Self-sustaining IL-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19.	JCI Insight	2021
34670579	Peritoneal metastasis of colorectal cancer (pmCRC): identification of predictive molecular signatures by a novel preclinical platform of matching pmCRC PDX/PD3D models.	Molecular Cancer	2021
34391889	A Universal Peptide Matrix Interactomics Approach to Disclose Motif-Dependent Protein Binding.	Molecular and Cellular Proteomics	2021
34846918	Multiomic characterization of oncogenic signaling mediated by wild-type and mutant RIT1.	Sci Signal	2021
34762513	CARDIOKIN1: Computational Assessment of Myocardial Metabolic Capability in Healthy Controls and Patients With Valve Diseases.	Circulation	2021
34698766	GAS1 is required for NOTCH-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium.	Development (Cambridge)	2021
33113356	Pairwise Stimulations of Pathogen-Sensing Pathways Predict Immune Responses to Multi-adjuvant Combinations.		2020
32203420	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	Nat Cell Biol	2020
31915069	Correction to: Comprehensive gene expression meta-analysis identifies signature genes that distinguish microglia from peripheral monocytes/macrophages in health and glioma.	Acta Neuropathol Commun	2020
31953384	Rapid and deep-scale ubiquitylation profiling for biology and translational research.	Nat Commun	2020
32060170	The VGF-derived Peptide TLQP21 Impairs Purinergic Control of Chemotaxis and Phagocytosis in Mouse Microglia.	Journal of Neuroscience	2020
32164329	Cyclin-Dependent Kinase 18 Controls Trafficking of Aquaporin-2 and Its Abundance through Ubiquitin Ligase STUB1, Which Functions as an AKAP.	Cells	2020
31924766	Cold-induced urticarial autoinflammatory syndrome related to factor XII activation.	Nature Communications	2020
31662325	Phosphorylation of RAB7 by TBK1/IKKÎµ Regulates Innate Immune Signaling in Triple-Negative Breast Cancer.	Cancer Res	2020
32471029	Progression-Dependent Altered Metabolism in Osteosarcoma Resulting in Different Nutrient Source Dependencies.	Cancers	2020
32969280	Proteomic Analysis Reveals Upregulation of ACE2 (Angiotensin-Converting Enzyme 2), the Putative SARS-CoV-2 Receptor in Pressure-but Not Volume-Overloaded Human Hearts.	Hypertension	2020