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Author Details

Ashok Kumar Jayavelu
German Cancer Research Center (DKFZ)
2014
24
10
PMIDPaper TitleJournal TitlePublished Year
36599833Unique ligand and kinase-independent roles of the insulin receptor in regulation of cell cycle, senescence and apoptosis.Nat Commun2023
37756525Germ line variant GFI1-36N affects DNA repair and sensitizes AML cells to DNA damage and repair therapy.Blood2023
38049829Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia.Mol Cancer2023
36958250Low level of antioxidant capacity biomarkers but not target overexpression predicts vulnerability to ROS-inducing drugs.Redox Biol2023
37422628Combined proteomics and CRISPRâ¿¿Cas9 screens in PDX identify ADAM10 as essential for leukemia in vivo.Mol Cancer2023
34695195PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.Blood2022
35511748HIP1R and vimentin immunohistochemistry predict 1p/19q status in IDH-mutant glioma.Neuro Oncol2022
35654819Histone demethylase KDM4C is a functional dependency in JAK2-mutated neoplasms.Leukemia2022
36333584In vivo PDX CRISPR/Cas9 screens reveal mutual therapeutic targets to overcome heterogeneous acquired chemo-resistance.Leukemia2022
36003783Presence of the <i>GFI1-36N</i> single nucleotide polymorphism enhances the response of <i>MLL-AF9</i> leukemic cells to CDK4/6 inhibition.Front Oncol2022
35279202Adverse stem cell clones within a single patient's tumor predict clinical outcome in AML patients.J Hematol Oncol2022
35245447The proteogenomic subtypes of acute myeloid leukemia.Cancer Cell2022
34465866YBX1 mediates translation of oncogenic transcripts to control cell competition in AML.Leukemia2022
34506305Signaling defects associated with insulin resistance in nondiabetic and diabetic individuals and modification by sex.J Clin Invest2021
32888406A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes.Cell Metab2020
31836852SHP1 regulates a STAT6-ITGB3 axis in FLT3ITD-positive AML cells.Leukemia2020
33239784Splicing factor YBX1 mediates persistence of JAK2-mutated neoplasms.Nature2020
29285262Nuclear membrane-localised NOX4D generates pro-survival ROS in FLT3-ITD-expressing AML.Oncotarget2017
28460451Synergistic killing of FLT3ITD-positive AML cells by combined inhibition of tyrosine-kinase activity and N-glycosylation.Oncotarget2017
27666490NOX-driven ROS formation in cell transformation of FLT3-ITD-positive AML.Exp Hematol2016
26308771NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells.Leukemia2016
26083014RNA expression of genes involved in cytarabine metabolism and transport predicts cytarabine response in acute myeloid leukemia.Pharmacogenomics2015
23793916ABCB6 RNA expression in leukemias--expression is low in acute promyelocytic leukemia and FLT3-ITD-positive acute myeloid leukemia.Ann Hematol2014
23998253Novel NPM1 mutation in the 3'-untranslated region identified in two patients with acute myeloid leukemia.Leuk Lymphoma2014
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Collaborators

Matthias Mann
Max-Planck Institute of Biochemistry
Co-authored papers 5
Jonathan M Dreyfuss
Joslin Diabetes Center, Harvard Medical School
Co-authored papers 3
Christoph R??llig
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 2
Michael Heuser
Hannover Medical School
Co-authored papers 2
Scott A Armstrong
Boston Children's Hospital
Co-authored papers 2
Bertram Opalka
University Hospital Essen.
Co-authored papers 2
Xiaoqing Xie
University Hospital Munster
Co-authored papers 2
Jana H??ve
University of Munster
Co-authored papers 2
Cyrus Khandanpour
University Hospital of Muenster
Co-authored papers 2
Daria Frank
University Hospital Muenster
Co-authored papers 2
Pradeep Kumar Patnana
University Munster
Co-authored papers 2
Desiree Kunadt
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 1
Joshua W Knowles
Co-authored papers 1
Felix Sahm
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 1
Alessandro Ori
Leibniz Institute on Aging - Fritz Lipmann Institute (FLI)
Co-authored papers 1
Julian Varghese
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 1
Amit U Sinha
Memorial Sloan Kettering Cancer Center
Co-authored papers 1
Sven Diederichs
Medical Center - University of Freiburg, University of Freiburg
Co-authored papers 1
Stefan Hutter
University Hospital
Co-authored papers 1
Frank Westermann
Co-authored papers 1
Doris Steinemann
Hannover Medical School
Co-authored papers 1
Ulrich D??hrsen
University Hospital Essen, University of Duisburg-Essen
Co-authored papers 1
J??rgen Klingauf
University of Munster
Co-authored papers 1
Lianghao Mao
German Cancer Research Center (DKFZ)
Co-authored papers 1
Kimberly Stegmaier
Dana-Farber Cancer Institute
Co-authored papers 1
Hauke Busch
Co-authored papers 1
Thomas Ernst
Universitatsklinikum Jena
Co-authored papers 1
Gudrun G??hring
Hannover Medical School
Co-authored papers 1
Georg Lenz
University Hospital of Muenster
Co-authored papers 1
Matthias Mann
Max-Planck-Institute of Biochemistry Munich
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