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Author Details

Un Seng Chio
University of California san francisco
2014
20
9
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36805129Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps.Structure2023
37696956Nucleosome density shapes kilobase-scale regulation by a mammalian chromatin remodeler.Nat Struct Mol Biol2023
37546986Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking.bioRxiv2023
37058572Cryo-EM structure of the human Sirtuin 6-nucleosome complex.Sci Adv2023
36993468Cryo-EM structure of the human Sirtuin 6-nucleosome complex.bioRxiv2023
37384669Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility.Science2023
37163603Dodecamer assembly of a metazoan AAA<sup>+</sup> chaperone couples substrate extraction to refolding.Sci Adv2023
35982665Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps.bioRxiv2022
34031651CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.Res Sq2021
34614151Subunit cooperation in the Get1/2 receptor promotes tail-anchored membrane protein insertion.J Cell Biol2021
34013269CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.bioRxiv2021
32817938An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation.bioRxiv2020
33060197Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.Science2020
33154106An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.Science2020
30605684A Chaperone Lid Ensures Efficient and Privileged Client Transfer during Tail-Anchored Protein Targeting.Cell Rep2019
30253068In vitro Assays for Targeting and Insertion of Tail-Anchored Proteins Into the ER Membrane.Curr Protoc Cell Biol2018
28973888A protean clamp guides membrane targeting of tail-anchored proteins.Proc Natl Acad Sci U S A2017
28992441Mechanisms of Tail-Anchored Membrane Protein Targeting and Insertion.Annu Rev Cell Dev Biol2017
27925580Multiple selection filters ensure accurate tail-anchored membrane protein targeting.Elife2016
25368153Differential gradients of interaction affinities drive efficient targeting and recycling in the GET pathway.Proc Natl Acad Sci U S A2014
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Collaborators

Gregory E Merz
University of California san francisco
Co-authored papers 7
Alexandrea N Rizo
University of California san francisco
Co-authored papers 7
Sergei Pourmal
University of California san francisco
Co-authored papers 7
Amber M Smith
University of California san francisco
Co-authored papers 7
Axel F Brilot
University of California san francisco
Co-authored papers 7
Yifan Cheng
Quantitative Bioscience Institute, University of California san francisco
Co-authored papers 6
Aashish Manglik
Department of Pharmaceutical Chemistry, University of California San Francisco
Co-authored papers 5
Zanlin Yu
University of California at San Francisco
Co-authored papers 5
Kaitlin Schaefer
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 5
Tanja Kortemme
University of California san francisco
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Danielle L Swaney
J. David Gladstone Institutes
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Kliment A Verba
University of California, University of California San Francisco
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Kaihua Zhang
Henan Normal University
Co-authored papers 5
Raphael Trenker
Cardiovascular Research Institute, University of California San Francisco
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Komal Ishwar Pawar
University of California san francisco
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Huong T Kratochvil
Department of Pharmaceutical Chemistry, University of California-San Francisco
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Meghna Gupta
University of California san francisco
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Oren S Rosenberg
University of California san francisco
Co-authored papers 5
Caleigh M Azumaya
Fred Hutchinson Cancer Center
Co-authored papers 5
Cristina Puchades
University of California San Francisco (UCSF) School of Medicine
Co-authored papers 5
Christian B Billesb??lle
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 5
Henry C Nguyen
Shanghai Clinical Research and Trial Center
Co-authored papers 5
Fengbo Zhou
Washington University School of Medicine
Co-authored papers 5
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 5
David A Agard
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 4
Yanxin Liu
University of California san francisco
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Jocelyne Lopez
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Soumya G Remesh
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