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Author Details

Bruno C Medeiros
AbbVie Inc.
1996
177
43
PMIDPaper TitleJournal TitlePublished Year
36720090Activity of eftozanermin alfa plus venetoclax in preclinical models and patients with acute myeloid leukemia.Blood2023
37205201CD25 targeting with the afucosylated human IgG1 antibody RG6292 eliminates regulatory T cells and CD25+ blasts in acute myeloid leukemia.Front Oncol2023
34316017Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results.Leukemia2022
35583300Factors associated with risk and prognosis of intensive care unit admission in patients with acute leukemia: a Danish nationwide cohort study.Leuk Lymphoma2022
35410569Epidemiology of invasive fungal diseases in adults with newly diagnosed acute myeloid leukemia.Leuk Lymphoma2022
35834732Phase 1b, open-label study evaluating the safety and pharmacokinetics of atezolizumab (anti-PD-L1 antibody) administered in combination with Hu5F9-G4 to patients with relapsed and/or refractory acute myeloid leukemia.Leuk Lymphoma2022
35467243Eftozanermin alfa (ABBV-621) monotherapy in patients with previously treated solid tumors: findings of a phase 1, first-in-human study.Invest New Drugs2022
35491816A phase 1b study of atezolizumab in combination with guadecitabine for the treatment of acute myeloid leukemia.Leuk Lymphoma2022
35922444Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial.Leukemia2022
33870413Plasma Microbial Cell-free DNA Next-generation Sequencing in the Diagnosis and Management of Febrile Neutropenia.Clin Infect Dis2022
34932793Atezolizumab alone or in combination did not demonstrate a favorable risk-benefit profile in myelodysplastic syndrome.Blood Adv2022
34351368Multisite 11-year experience of less-intensive vs intensive therapies in acute myeloid leukemia.Blood2021
33654204Midostaurin reduces relapse in FLT3-mutant acute myeloid leukemia: the Alliance CALGB 10603/RATIFY trial.Leukemia2021
32543932Venetoclax and hypomethylating agent therapy in high risk myelodysplastic syndromes: a retrospective evaluation of a real-world experience.Leuk Lymphoma2020
31804723Increased mitochondrial apoptotic priming with targeted therapy predicts clinical response to re-induction chemotherapy.Am J Hematol2020
31980503Functional characterization of two rare BCR-FGFR1<sup>+</sup> leukemias.Cold Spring Harb Mol Case Stud2020
31826241Impact of NPM1/FLT3-ITD genotypes defined by the 2017 European LeukemiaNet in patients with acute myeloid leukemia.Blood2020
33049054Midostaurin in patients with acute myeloid leukemia and FLT3-TKD mutations: a subanalysis from the RATIFY trial.Blood Adv2020
32281456Economic and Clinical Burden of Acute Myeloid Leukemia Episodes of Care in the United States: A Retrospective Analysis of a Commercial Payer Database.J Manag Care Spec Pharm2020
32150611Single-cell mutational profiling enhances the clinical evaluation of AML MRD.Blood Adv2020
30673620The relationship between clinical trial accrual volume and outcomes in acute myeloid leukemia: A SWOG/ECOG-ACRIN study (S0106 and E1900).Leuk Res2019
31695504Longer distance to specialized treatment centers does not adversely affect treatment intensity or outcomes in adult acute myeloid leukemia patients. A Danish national population-based cohort study.Clin Epidemiol2019
30203489Safety and efficacy of vismodegib in relapsed/refractory acute myeloid leukaemia: results of a phase Ib trial.Br J Haematol2019
31291378Acute myeloid leukemia immunopeptidome reveals HLA presentation of mutated nucleophosmin.PLoS One2019
31541945Safety and efficacy of oral panobinostat plus chemotherapy in patients aged 65 years or younger with high-risk acute myeloid leukemia.Leuk Res2019
31366621Genomic landscape of neutrophilic leukemias of ambiguous diagnosis.Blood2019
31222713Economic and Clinical Burden of Relapsed and/or Refractory Active Treatment Episodes in Patients with Acute Myeloid Leukemia (AML) in the USA: A Retrospective Analysis of a Commercial Payer Database.Adv Ther2019
30712406Treatment patterns in patients with acute myeloid leukemia in the United States: a cross-sectional, real-world survey.Curr Med Res Opin2019
30945331Optimizing survival outcomes with post-remission therapy in acute myeloid leukemia.Am J Hematol2019
30887583Addressing the room for improvement in management of acute promyelocytic leukemia.Eur J Haematol2019
30760466Pracinostat plus azacitidine in older patients with newly diagnosed acute myeloid leukemia: results of a phase 2 study.Blood Adv2019
28744009Efficacy and safety of midostaurin in patients with advanced systemic mastocytosis: 10-year median follow-up of a phase II trial.Leukemia2018
30024784CPX-351 (cytarabine and daunorubicin) Liposome for Injection Versus Conventional Cytarabine Plus Daunorubicin in Older Patients With Newly Diagnosed Secondary Acute Myeloid Leukemia.J Clin Oncol2018
30212655Chemotherapy based combinations in AML: Time to take a step back?Leuk Res2018
29802551A phase I, open-label, dose-escalation study of amrubicin in combination with lenalidomide and weekly dexamethasone in previously treated adults with relapsed or refractory multiple myeloma.Int J Hematol2018
30115633Non-zero-sum game of transfusions: EOL in leukemia.Blood2018
30464604NSAID consumption and risk of acute myeloid leukemia: a national population-based case-control study.Cancer Manag Res2018
30333627Functional genomic landscape of acute myeloid leukaemia.Nature2018
30466752Is there a standard of care for relapsed AML?Best Pract Res Clin Haematol2018
29504124Autoimmune diseases, infections, use of antibiotics and the risk of acute myeloid leukaemia: a national population-based case-control study.Br J Haematol2018
29524739Interpretation of clinical endpoints in trials of acute myeloid leukemia.Leuk Res2018
29695517Associations between cohabitation status, treatment, and outcome in AML patients: a national population-based study.Blood2018
29572158A Phase I/II Trial of the Combination of Azacitidine and Gemtuzumab Ozogamicin for Treatment of Relapsed Acute Myeloid Leukemia.Clin Lymphoma Myeloma Leuk2018
29407182Report of the relapsed/refractory cohort of SWOG S0919: A phase 2 study of idarubicin and cytarabine in combination with pravastatin for acute myelogenous leukemia (AML).Leuk Res2018
29454474Cardiovascular, pulmonary, and metabolic toxicities complicating tyrosine kinase inhibitor therapy in chronic myeloid leukemia: Strategies for monitoring, detecting, and managing.Blood Rev2018
29051022Impact of Allogeneic Stem Cell Transplantation in First Complete Remission in Acute Myeloid Leukemia: A National Population-Based Cohort Study.Biol Blood Marrow Transplant2018
29097499Randomized study of continuous high-dose lenalidomide, sequential azacitidine and lenalidomide, or azacitidine in persons 65 years and over with newly-diagnosed acute myeloid leukemia.Haematologica2018
29242304Unsatisfactory efficacy in randomized study of reduced-dose CPX-351 for medically less fit adults with newly diagnosed acute myeloid leukemia or other high-grade myeloid neoplasm.Haematologica2018
27721426Isocitrate dehydrogenase mutations in myeloid malignancies.Leukemia2017
28355571Identification of Interleukin-1 by Functional Screening as a Key Mediator of Cellular Expansion and Disease Progression in Acute Myeloid Leukemia.Cell Rep2017
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Collaborators

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Dana Farber Cancer Institute
Co-authored papers 11
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Oregon Health and Science University
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University of Texas Southwestern Medical Center
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Oregon Health & Science University
Co-authored papers 4
Hannover Medical School
Co-authored papers 4
University of Kansas Medical Center
Co-authored papers 4
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 4
Oregon Health & Science University, University of California Berkeley
Co-authored papers 4
University of Utah Huntsman Cancer Institute
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Toronto General Hospital, University Health Network, University of Toronto
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Feinberg School of Medicine, Northwestern University
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Division of Clinical Trials and Biostatistics, Mayo Clinic
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