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Author Details
Full Name
Robert M Stroud
Affiliation
University of California San Francisco
ORCID
Career Start Year
1965
Papers
358
H Index
89
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36747776
Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13.
bioRxiv
2023
36965620
Substrate recognition and proton coupling by a bacterial member of solute carrier family 17.
J Biol Chem
2023
36782050
Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13.
Nat Struct Mol Biol
2023
34964607
Symmetry Reduction in a Hyperpolarization-Activated Homotetrameric Ion Channel.
Biochemistry
2022
35660266
Diversity of function and mechanism in a family of organic anion transporters.
Curr Opin Struct Biol
2022
36475542
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth.
Elife
2022
35210362
Molecular basis of multistep voltage activation in plant two-pore channel 1.
Proc Natl Acad Sci U S A
2022
34135124
Key computational findings reveal proton transfer as driving the functional cycle in the phosphate transporter PiPT.
Proc Natl Acad Sci U S A
2021
33829766
Caught in Action: X-ray Structure of Thymidylate Synthase with Noncovalent Intermediate Analog.
Biochemistry
2021
33744283
Highlighting membrane protein structure and function: A celebration of the Protein Data Bank.
J Biol Chem
2021
33876770
Structural basis for <i>Clostridium perfringens</i> enterotoxin targeting of claudins at tight junctions in mammalian gut.
Proc Natl Acad Sci U S A
2021
34013269
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
bioRxiv
2021
34319067
Allosteric Inhibition of a Vesicular Glutamate Transporter by an Isoform-Specific Antibody.
Biochemistry
2021
32380514
Diversity in kinetics correlated with structure in nano body-stabilized LacY.
PLoS One
2020
31924746
Resting state structure of the hyperdepolarization activated two-pore channel 3.
Proc Natl Acad Sci U S A
2020
33060197
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Science
2020
32439795
Ion transport and regulation in a synaptic vesicle glutamate transporter.
Science
2020
32353859
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
Nature
2020
31083648
Structures suggest a mechanism for energy coupling by a family of organic anion transporters.
PLoS Biol
2019
31267462
High-Throughput Nano-Scale Characterization of Membrane Proteins Using Fluorescence-Detection Size-Exclusion Chromatography.
Methods Mol Biol
2019
31434788
Claudin-9 structures reveal mechanism for toxin-induced gut barrier breakdown.
Proc Natl Acad Sci U S A
2019
31149896
Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether.
Elife
2019
28656706
On the structure and mechanism of two-pore channels.
FEBS J
2018
30166453
CRL4<sup>AMBRA1</sup> targets Elongin C for ubiquitination and degradation to modulate CRL5 signaling.
EMBO J
2018
30190435
Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc Natl Acad Sci U S A
2018
30108145
Crystal Structure of a ligand-bound LacY-Nanobody Complex.
Proc Natl Acad Sci U S A
2018
29717875
A Single Mutation Traps a Half-Sites Reactive Enzyme in Midstream, Explaining Asymmetry in Hydride Transfer.
Biochemistry
2018
28069938
Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP.
Proc Natl Acad Sci U S A
2017
27078104
Mechanism of inhibition of human glucose transporter GLUT1 is conserved between cytochalasin B and phenylalanine amides.
Proc Natl Acad Sci U S A
2016
27692964
The Preserved HTH-Docking Cleft of HIV-1 Integrase Is Functionally Critical.
Structure
2016
27601653
Structure of Bor1 supports an elevator transport mechanism for SLC4 anion exchangers.
Proc Natl Acad Sci U S A
2016
27129281
Modulation of P2X3 and P2X2/3 Receptors by Monoclonal Antibodies.
J Biol Chem
2016
27485338
Small-Scale Screening to Large-Scale Over-Expression of Human Membrane Proteins for Structural Studies.
Methods Mol Biol
2016
27485336
Integral Membrane Protein Expression in Saccharomyces cerevisiae.
Methods Mol Biol
2016
26961658
Structure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thaliana.
Nature
2016
25363761
Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter.
Nature
2015
26528243
Fungal association and utilization of phosphate by plants: success, limitations, and future prospects.
Front Microbiol
2015
26470919
Crystal Structure of the Human tRNA m(1)A58 Methyltransferase-tRNA(3)(Lys) Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target.
J Mol Biol
2015
26157133
Structure of LacY with an α-substituted galactoside: Connecting the binding site to the protonation site.
Proc Natl Acad Sci U S A
2015
25865481
Substrates Control Multimerization and Activation of the Multi-Domain ATPase Motor of Type VII Secretion.
Cell
2015
25798950
Hotspots in an obligate homodimeric anticancer target. Structural and functional effects of interfacial mutations in human thymidylate synthase.
J Med Chem
2015
25427005
Alanine mutants of the interface residues of human thymidylate synthase decode key features of the binding mode of allosteric anticancer peptides.
J Med Chem
2015
24214967
The mechanism of pseudouridine synthases from a covalent complex with RNA, and alternate specificity for U2605 versus U2604 between close homologs.
Nucleic Acids Res
2014
24994900
Structure of a new DNA-binding domain which regulates pathogenesis in a wide variety of fungi.
Proc Natl Acad Sci U S A
2014
25081745
General qPCR and Plate Reader Methods for Rapid Optimization of Membrane Protein Purification and Crystallization Using Thermostability Assays.
Curr Protoc Protein Sci
2014
25081744
Tetra detector analysis of membrane proteins.
Curr Protoc Protein Sci
2014
24613931
Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer.
Proc Natl Acad Sci U S A
2014
24453216
Structure of sugar-bound LacY.
Proc Natl Acad Sci U S A
2014
23542591
Crystal structure of a eukaryotic phosphate transporter.
Nature
2013
24173033
Structures of intermediate transport states of ZneA, a Zn(II)/proton antiporter.
Proc Natl Acad Sci U S A
2013
1 - 50 of 358
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University of California San Francisco
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Co-authored papers
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Co-authored papers
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University of California san francisco
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8
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Quantitative Bioscience Institute, University of California san francisco
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Zygy Roe-Zurz
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David A Agard
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Nevan J Krogan (CM4AI)
University of California San Francisco
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Meghna Gupta
University of California san francisco
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H R Kaback
University of California los angeles
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5
James H Hurley
University of California Berkeley
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5
Sarika Chaudhary
Bennett University
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Avner Schlessinger
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