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Author Details

Vincent Setola
West Virginia University School of Medicine
2001
72
31
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
33834276Preclinical Studies on Nalfurafine (TRK-820), a Clinically Used KOR Agonist.Handb Exp Pharmacol2022
32842837Genetic deletion of <i>Rgs12</i> in mice affects serotonin transporter expression and function <i>in vivo</i> and <i>ex vivo</i>.J Psychopharmacol2020
31137020Single Nucleotide Polymorphisms in Chemosensory Pathway Genes GNB3, TAS2R19, and TAS2R38 Are Associated with Chronic Rhinosinusitis.Int Arch Allergy Immunol2019
31408461A role for Regulator of G protein Signaling-12 (RGS12) in the balance between myoblast proliferation and differentiation.PLoS One2019
31492823Preclinical Testing of Nalfurafine as an Opioid-sparing Adjuvant that Potentiates Analgesia by the Mu Opioid Receptor-targeting Agonist Morphine.J Pharmacol Exp Ther2019
31057342Four single nucleotide polymorphisms in genes involved in neuronal signaling are associated with Opioid Use Disorder in West Virginia.J Opioid Manag2019
31141817Role of RGS12 in the differential regulation of kappa opioid receptor-dependent signaling and behavior.Neuropsychopharmacology2019
29566092Correction: The Ketamine Analogue Methoxetamine and 3- and 4-Methoxy Analogues of Phencyclidine Are High Affinity and Selective Ligands for the Glutamate NMDA Receptor.PLoS One2018
29364035Regulator of G protein signaling-12 modulates the dopamine transporter in ventral striatum and locomotor responses to psychostimulants.J Psychopharmacol2018
29701767Development of Full Sweet, Umami, and Bitter Taste Responsiveness Requires Regulator of G protein Signaling-21 (RGS21).Chem Senses2018
26821282Genetic variations in GPSM3 associated with protection from rheumatoid arthritis affect its transcript abundance.Genes Immun2016
27147738Identification and Validation of Small Molecules That Enhance Recombinant Adeno-associated Virus Transduction following High-Throughput Screens.J Virol2016
27307211Reduction of GPSM3 expression akin to the arthritis-protective SNP rs204989 differentially affects migration in a neutrophil model.Genes Immun2016
26488584Correction: Exome Sequencing in 53 Sporadic Cases of Schizophrenia Identifies 18 Putative Candidate Genes.PLoS One2015
23908053RGS21, a regulator of taste and mucociliary clearance?Laryngoscope2014
25420024Exome sequencing in 53 sporadic cases of schizophrenia identifies 18 putative candidate genes.PLoS One2014
25193297Michael acceptor approach to the design of new salvinorin A-based high affinity ligands for the kappa-opioid receptor.Eur J Med Chem2014
25070422Further evaluation of the tropane analogs of haloperidol.Bioorg Med Chem Lett2014
24800940Identification of a new selective dopamine D4 receptor ligand.Bioorg Med Chem2014
24174497Role of the N-terminal region in G protein-coupled receptor functions: negative modulation revealed by 5-HT2B receptor polymorphisms.Mol Pharmacol2014
22445074Labdane diterpenoids from Leonotis leonurus.Phytochemistry2013
23602445An analysis of the synthetic tryptamines AMT and 5-MeO-DALT: emerging 'Novel Psychoactive Drugs'.Bioorg Med Chem Lett2013
23396078Photochemical activation of TRPA1 channels in neurons and animals.Nat Chem Biol2013
23527166The ketamine analogue methoxetamine and 3- and 4-methoxy analogues of phencyclidine are high affinity and selective ligands for the glutamate NMDA receptor.PLoS One2013
23261499Neurochemical profiles of some novel psychoactive substances.Eur J Pharmacol2013
21537332Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice.Mol Psychiatry2012
23235874Automated design of ligands to polypharmacological profiles.Nature2012
229406055-HT(2B) antagonism arrests non-canonical TGF-β1-induced valvular myofibroblast differentiation.J Mol Cell Cardiol2012
22711801Identifying mechanism-of-action targets for drugs and probes.Proc Natl Acad Sci U S A2012
22738628Moderate chemical modifications of WAY-100635 improve the selectivity for 5-HT1A versus D4 receptors.Bioorg Med Chem Lett2012
22738238Orally active adenosine A(1) receptor agonists with antinociceptive effects in mice.J Med Chem2012
22845053Structure-functional selectivity relationship studies of β-arrestin-biased dopamine D⿿ receptor agonists.J Med Chem2012
22537153Chemocentric informatics approach to drug discovery: identification and experimental validation of selective estrogen receptor modulators as ligands of 5-hydroxytryptamine-6 receptors and as potential cognition enhancers.J Med Chem2012
22475308Bis-spirolabdane diterpenoids from Leonotis nepetaefolia.J Nat Prod2012
22520153Benzothiazoles as probes for the 5HT1A receptor and the serotonin transporter (SERT): a search for new dual-acting agents as potential antidepressants.Eur J Med Chem2012
22245230Multi-receptor drug design: Haloperidol as a scaffold for the design and synthesis of atypical antipsychotic agents.Bioorg Med Chem2012
22336245Structure-activity relationship studies of SYA 013, a homopiperazine analog of haloperidol.Bioorg Med Chem2012
21048700The presynaptic component of the serotonergic system is required for clozapine's efficacy.Neuropsychopharmacology2011
22832607Schizophrenia risk gene CAV1 is both pro-psychotic and required for atypical antipsychotic drug actions in vivo.Transl Psychiatry2011
22025698Discovery of β-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy.Proc Natl Acad Sci U S A2011
22179068Chemical informatics and target identification in a zebrafish phenotypic screen.Nat Chem Biol2011
21926995Ligand discovery from a dopamine D3 receptor homology model and crystal structure.Nat Chem Biol2011
21609016Design, synthesis, and validation of a β-turn mimetic library targeting protein-protein and peptide-receptor interactions.J Am Chem Soc2011
21368188Synthesis and receptor profiling of Stemona alkaloid analogues reveal a potent class of sigma ligands.Proc Natl Acad Sci U S A2011
21440001Serotonin receptors and heart valve disease--it was meant 2B.Pharmacol Ther2011
20958049Development, validation, and use of quantitative structure-activity relationship models of 5-hydroxytryptamine (2B) receptor ligands to identify novel receptor binders and putative valvulopathic compounds among common drugs.J Med Chem2010
21158687Identification of human Ether-à-go-go related gene modulators by three screening platforms in an academic drug-discovery setting.Assay Drug Dev Technol2010
20729985N-Alkyl-octahydroisoquinolin-1-one-8-carboxamides: a Novel Class of Selective, Nonbasic, Nitrogen-Containing κ-Opioid Receptor Ligands.ACS Med Chem Lett2010
20692833N-tetrahydrothiochromenoisoxazole-1-carboxamides as selective antagonists of cloned human 5-HT2B.Bioorg Med Chem Lett2010
19023134Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy.Circ Res2009
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INSERM
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Polish Academy of Sciences
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Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
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