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Author Details

Nikolai Engedal
Institute for Cancer Research, Oslo University Hospital
1998
50
25
PMIDPaper TitleJournal TitlePublished Year
37459465Analysis of ATG4C function <i>in vivo</i>.Autophagy2023
35340207Transautophagy: Research and Translation of Autophagy Knowledge 2020.Oxid Med Cell Longev2022
35697807Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression.Nat Biotechnol2022
34972988Measuring Autophagic Cargo Flux with Keima-Based Probes.Methods Mol Biol2022
35332208AXL inhibition improves BRAF-targeted treatment in melanoma.Sci Rep2022
34489465Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse.Nat Commun2021
33907223ALK inhibition activates LC3B-independent, protective autophagy in EML4-ALK positive lung cancer cells.Sci Rep2021
33797641From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development.Prog Chem Org Nat Prod2021
31366282ESCRT-mediated phagophore sealing during mitophagy.Autophagy2020
31987044Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components.Cell Commun Signal2020
32245178Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot.Biology (Basel)2020
30610706Measurement of Bulk Autophagy by a Cargo Sequestration Assay.Methods Mol Biol2019
30926605The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress.J Biol Chem2019
30760074Small variations in nanoparticle structure dictate differential cellular stress responses and mode of cell death.Nanotoxicology2019
29682156The Role of Free Radicals in Autophagy Regulation: Implications for Ageing.Oxid Med Cell Longev2018
34286043The Long-lived Protein Degradation Assay: an Efficient Method for Quantitative Determination of the Autophagic Flux of Endogenous Proteins in Adherent Cell Lines.Bio Protoc2018
34286042An Image-based Assay for High-throughput Analysis of Cell Proliferation and Cell Death of Adherent Cells.Bio Protoc2018
30102280The Lactate Dehydrogenase Sequestration Assay - A Simple and Reliable Method to Determine Bulk Autophagic Sequestration Activity in Mammalian Cells.J Vis Exp2018
29940786Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion.Autophagy2018
29861835Transautophagy: Research and Translation of Autophagy Knowledge.Oxid Med Cell Longev2018
29849898From Oxidative Stress Damage to Pathways, Networks, and Autophagy via MicroRNAs.Oxid Med Cell Longev2018
30261424Nonlinear relationship between ER Ca<sup>2+</sup> depletion versus induction of the unfolded protein response, autophagy inhibition, and cell death.Cell Calcium2018
30513588The ER Stress Inducer l-Azetidine-2-Carboxylic Acid Elevates the Levels of Phospho-eIF2α and of LC3-II in a Ca<sup>2+</sup>-Dependent Manner.Cells2018
28516064A Novel Role of <i>Listeria monocytogenes</i> Membrane Vesicles in Inhibition of Autophagy and Cell Death.Front Cell Infect Microbiol2017
28253965A Simple Cargo Sequestration Assay for Quantitative Measurement of Nonselective Autophagy in Cultured Cells.Methods Enzymol2017
28972171Inhibition of the sarco/endoplasmic reticulum (ER) Ca<sup>2+</sup>-ATPase by thapsigargin analogs induces cell death via ER Ca<sup>2+</sup> depletion and the unfolded protein response.J Biol Chem2017
28835545Rab7b modulates autophagic flux by interacting with Atg4B.EMBO Rep2017
26237084Autophagy of cytoplasmic bulk cargo does not require LC3.Autophagy2016
26799652Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).Autophagy2016
25241896UAP1 is overexpressed in prostate cancer and is protective against inhibitors of N-linked glycosylation.Oncogene2015
25684710Autophagic bulk sequestration of cytosolic cargo is independent of LC3, but requires GABARAPs.Exp Cell Res2015
25779646Novel steps in the autophagic-lysosomal pathway.FEBS J2015
25576638Macroautophagic cargo sequestration assays.Methods2015
24377925Endosomal signaling and oncogenesis.Methods Enzymol2014
23593995The ERM proteins ezrin and moesin regulate retrograde Shiga toxin transport.Traffic2013
23970379Targeting autophagy potentiates the apoptotic effect of histone deacetylase inhibitors in t(8;21) AML cells.Blood2013
23970164Modulation of intracellular calcium homeostasis blocks autophagosome formation.Autophagy2013
21255370Shiga toxin and its use in targeted cancer therapy and imaging.Microb Biotechnol2011
21419271Immune regulator vitamin A and T cell death.Vitam Horm2011
21054580Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells.FEMS Immunol Med Microbiol2011
20385131Protein toxins from plants and bacteria: probes for intracellular transport and tools in medicine.FEBS Lett2010
19112091Retinoic acid regulates Fas-induced apoptosis in Jurkat T cells: reversal of mitogen-mediated repression of Fas DISC assembly.J Leukoc Biol2009
16920920All-trans retinoic acid stimulates IL-2-mediated proliferation of human T lymphocytes: early induction of cyclin D3.J Immunol2006
14978018Survival of activated human T lymphocytes is promoted by retinoic acid via induction of IL-2.Int Immunol2004
12551910Combined action of ERK and NF kappa B mediates the protective effect of phorbol ester on Fas-induced apoptosis in Jurkat cells.J Biol Chem2003
11850819C-Jun N-terminal kinase is required for phorbol ester- and thapsigargin-induced apoptosis in the androgen responsive prostate cancer cell line LNCaP.Oncogene2002
12421932Retinoic acid stimulates the cell cycle machinery in normal T cells: involvement of retinoic acid receptor-mediated IL-2 secretion.J Immunol2002
11241551Ceramide-induced cell death in the prostate cancer cell line LNCaP has both necrotic and apoptotic features.Prostate2001
10754526Efficient DNA-mediated gene transfer into prostate cancer cell line LNCaP.Prostate2000
9822653CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1.J Biol Chem1998
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Collaborators

Queen's University Belfast
Co-authored papers 6
Jozef Stefan Institute
Co-authored papers 4
Northwestern University Feinberg School of Medicine Chicago
Co-authored papers 3
Prostate Cancer Research Center, Tampere University and Tays Cancer Center
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Francis Crick Institute
Co-authored papers 2
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Co-authored papers 2
Universite Cote d'Azur, INSERM U5
Co-authored papers 2
Institute for Cancer Research, Oslo University Hospital
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
the University of Texas MD Anderson Cancer Center
Co-authored papers 2
Instituto Universitario de Oncologia, Universidad de Oviedo
Co-authored papers 2
Institute of Human Genetics, University Hospital Heidelberg
Co-authored papers 1
university of california san diego Health System
Co-authored papers 1
and Barnett Institute, Northeastern University
Co-authored papers 1
The Microsoft Research University of Trento
Co-authored papers 1
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 1
Armed Forces Radiobiology Research Institute
Co-authored papers 1
Harvard Medical School
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Oncode Institute
Co-authored papers 1
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
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The Institute of Cancer Research
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New York State Psychiatric Institute, Research Foundation for Mental Hygiene
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Australian Institute for Bioengineering and Nanotechnology, University of Queensland
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Walter and Eliza Hall Institute of Medical Research
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University of California san francisco
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University of Pennsylvania
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