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Author Details

Carl F Ware
Sanford Burnham Prebys Medical Discovery Institute
1977
254
80
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37279757Epitope topography of agonist antibodies to the checkpoint inhibitory receptor BTLA.Structure2023
34871182Randomized, double-blind, controlled trial of human anti-LIGHT monoclonal antibody in COVID-19 acute respiratory distress syndrome.J Clin Invest2022
35604387Realigning the LIGHT signaling network to control dysregulated inflammation.J Exp Med2022
36704666Three-dimensional Imaging Reveals Immune-driven Tumor-associated High Endothelial Venules as a Key Correlate of Tumor Rejection Following Depletion of Regulatory T Cells.Cancer Res Commun2022
35320716Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa.Cell Rep2022
34907396Retraction Note: Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma.Nat Neurosci2022
34526403Posttranslational modifications by ADAM10 shape myeloid antigen-presenting cell homeostasis in the splenic marginal zone.Proc Natl Acad Sci U S A2021
33822844Regnase-1 is essential for B cell homeostasis to prevent immunopathology.J Exp Med2021
33753412Lymphotoxin β Receptor: a Crucial Role in Innate and Adaptive Immune Responses against Toxoplasma gondii.Infect Immun2021
33724364ILC3s control splenic cDC homeostasis via lymphotoxin signaling.J Exp Med2021
34528674Development of follicular dendritic cells in lymph nodes depends on retinoic acid-mediated signaling.Development2021
32424282Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma.Nat Neurosci2020
31969387Cutting Edge: The RNA-Binding Protein Ewing Sarcoma Is a Novel Modulator of Lymphotoxin β Receptor Signaling.J Immunol2020
31990039LIGHT/TNFSF14 regulates estrogen deficiency-induced bone loss.J Pathol2020
31826304LIGHT/TNFSF14 Promotes Osteolytic Bone Metastases in Non-small Cell Lung Cancer Patients.J Bone Miner Res2020
33298958Deletion of immune evasion genes provides an effective vaccine design for tumor-associated herpesviruses.NPJ Vaccines2020
33207209Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues.Immunity2020
32676079Contactin-1 Is Required for Peripheral Innervation and Immune Homeostasis Within the Intestinal Mucosa.Front Immunol2020
32817460Levels of the TNF-Related Cytokine LIGHT Increase in Hospitalized COVID-19 Patients with Cytokine Release Syndrome and ARDS.mSphere2020
32817296HVEM signaling promotes protective antibody-dependent cellular cytotoxicity (ADCC) vaccine responses to herpes simplex viruses.Sci Immunol2020
30829412Reply.Hepatology2019
31204070The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis.Immunity2019
31011203A signature of circulating inflammatory proteins and development of end-stage renal disease in diabetes.Nat Med2019
29178458Impairment of Bone Remodeling in LIGHT/TNFSF14-Deficient Mice.J Bone Miner Res2018
29742809B Cell-Mediated Maintenance of Cluster of Differentiation 169-Positive Cells Is Critical for Liver Regeneration.Hepatology2018
29514949The TNF Superfamily Molecule LIGHT Promotes the Generation of Circulating and Lung-Resident Memory CD8 T Cells following an Acute Respiratory Virus Infection.J Immunol2018
28864473HVEM Imprints Memory Potential on Effector CD8 T Cells Required for Protective Mucosal Immunity.J Immunol2017
28947544Treg Depletion Licenses T Cell-Driven HEV Neogenesis and Promotes Tumor Destruction.Cancer Immunol Res2017
29186687Perivascular Fibroblasts of the Developing Spleen Act as LTα1β2-Dependent Precursors of Both T and B Zone Organizer Cells.Cell Rep2017
29061848A herpesvirus entry mediator mutein with selective agonist action for the inhibitory receptor B and T lymphocyte attenuator.J Biol Chem2017
26206664LTβR signalling preferentially accelerates oncogenic AKT-initiated liver tumours.Gut2016
27678221The NF-κB subunit RelB controls p100 processing by competing with the kinases NIK and IKK1 for binding to p100.Sci Signal2016
27355755Deletion of P2Y2 receptor reveals a role for lymphotoxin-α in fatty streak formation.Vascul Pharmacol2016
27192566The TNF Receptor Superfamily in Co-stimulating and Co-inhibitory Responses.Immunity2016
27549174Lymphotoxin β Receptor Controls T Cell Progenitor Entry to the Thymus.J Immunol2016
26799785A new HIF-1α/RANTES-driven pathway to hepatocellular carcinoma mediated by germline haploinsufficiency of SART1/HAF in mice.Hepatology2016
26789245Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation.Nature2016
25599993Commensal microbiota influence systemic autoimmune responses.EMBO J2015
26098211Interferon-induced mechanosensing defects impede apoptotic cell clearance in lupus.J Clin Invest2015
25673724Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infection.J Virol2015
25728676Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy.Oncogene2015
24307582Interactions between herpesvirus entry mediator (TNFRSF14) and latency-associated transcript during herpes simplex virus 1 latency.J Virol2014
25524549Tumor necrosis factor superfamily in innate immunity and inflammation.Cold Spring Harb Perspect Biol2014
25594025NLRs: Sentinels of innate immunity or cancer culprits?Oncoscience2014
25566265Mixing Signals: Molecular Turn Ons and Turn Offs for Innate γδ T-Cells.Front Immunol2014
25381434The thymic microenvironment differentially regulates development and trafficking of invariant NKT cell sublineages.J Immunol2014
25349408p100/IκBδ sequesters and inhibits NF-κB through kappaBsome formation.Proc Natl Acad Sci U S A2014
24875104Extracellular adenosine regulates colitis through effects on lymphoid and nonlymphoid cells.Am J Physiol Gastrointest Liver Physiol2014
24563505Pillars article: A lymphotoxin-B-specific receptor. Science. 1994. 264: 707-710.J Immunol2014
24681825The NLR-related protein NWD1 is associated with prostate cancer and modulates androgen receptor signaling.Oncotarget2014
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Collaborators

John R Sedy
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 15
Todd VanArsdale
Oncology Research Unit, Inc.
Co-authored papers 11
Jason G Cyster
University of California san francisco
Co-authored papers 4
Aleksandra A Pandyra
Hematology and Clinical Immunology, Heinrich-Heine University Dusseldorf
Co-authored papers 3
Peter Ghazal
UK System Immunity Research Institute, Cardiff University
Co-authored papers 2
Andrew J Mungall
Co-authored papers 2
Patricia Baxter
Texas Children's Cancer Center, Baylor College of Medicine
Co-authored papers 2
Michael D Taylor
The Hospital for Sick Children
Co-authored papers 2
Aniruddha J Deshpande
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Patryk Skowron
University of Toronto
Co-authored papers 2
Jessica M Rusert
University of California San Diego
Co-authored papers 2
Nina Thiessen
Co-authored papers 2
Richard A Moore
Co-authored papers 2
Drake Laface
Merck & Co. Inc.
Co-authored papers 2
John R Crawford
Rady Children's Hospital San Diego.
Co-authored papers 2
Tak W Mak
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
John D Lambris
Co-authored papers 2
Yussanne Ma
Co-authored papers 2
Anca Sorana Morrissy
Cumming School of Medicine, University of Calgary
Co-authored papers 2
Marco A Marra
University of British Columbia
Co-authored papers 2
Florence M G Cavalli
Institut Curie, PSL Research University
Co-authored papers 2
Steven J M Jones
University of British Columbia
Co-authored papers 2
Vijay Ramaswamy
Hospital for Sick Children
Co-authored papers 2
Paul G Thomas
St. Jude Children's Research Hospital
Co-authored papers 2
Robert J Wechsler-Reya
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Hamza Farooq
BioBox Analytics Inc.
Co-authored papers 2
Xiao-Nan Li
Northwestern University
Co-authored papers 2
James M Olson
Clinical Research Division, Fred Hutchinson Cancer Center
Co-authored papers 2
Lin Qi
Xiangya Hospital of Central South University
Co-authored papers 2
Shane Raines
AstraZeneca Pharmaceuticals
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Release 1.2