Author details

Full Name

Michael Ott

Affiliation

ORCID

Career Start Year

1996

Papers

113

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36994536	Cell atlas of CCl <sub>4</sub>-induced progressive liver fibrosis reveals stage-specific responses.	Zool Res	2023
35976053	Adeno-associated virus serotype 2 capsid variants for improved liver-directed gene therapy.	Hepatology	2023
37146576	Bioartificial liver with reprogrammed hepatocytes ready for prime time.		2023
35053588	Hepatocellular Carcinoma Is a Natural Target for Adeno-Associated Virus (AAV) 2 Vectors.	Cancers	2022
35397938	Corrigendum to: 'Hepatocyte-specific suppression of microRNA-221-3p mitigates liver fibrosis' [J Hepatol (2019) 722-734].	Journal of Hepatology	2022
35397937	Corrigendum to 'Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model' [J Hepatol (2021) 1420-1433].	J Hepatol	2022
36064805	In vivo adenine base editing reverts C282Y and improves iron metabolism in hemochromatosis mice.	Nature Communications	2022
34453962	Therapeutic HNF4A mRNA attenuates liver fibrosis in a preclinical model.	J Hepatol	2021
33507897	Correction: Pathological mechanism and antisense oligonucleotide-mediated rescue of a non-coding variant suppressing factor 9 RNA biogenesis leading to hemophilia B.	PLoS Genetics	2021
33927320	Direct conversion of porcine primary fibroblasts into hepatocyte-like cells.	Scientific Reports	2021
34306986	Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration.	Advanced Science	2021
32738449	MicroRNA-342-3p is a potent tumour suppressor in hepatocellular carcinoma.	J Hepatol	2021
32719439	microRNA-93-5p promotes hepatocellular carcinoma progression via a microRNA-93-5p/MAP3K2/c-Jun positive feedback circuit.	Oncogene	2020
32267853	Pathological mechanism and antisense oligonucleotide-mediated rescue of a non-coding variant suppressing factor 9 RNA biogenesis leading to hemophilia B.	PLoS Genetics	2020
31887661	ExÂ Vivo/InÂ vivo Gene Editing in Hepatocytes Using "All-in-One" CRISPR-Adeno-Associated Virus Vectors with a Self-Linearizing Repair Template.	iScience	2020
32386955	Equal opportunity offer for all hepatocytes.	Journal of Hepatology	2020
33148654	Liver-expressed <i>Cd302</i> and <i>Cr1l</i> limit hepatitis C virus cross-species transmission to mice.	Sci Adv	2020
33305155	MicroRNA-125b-5p Regulates Hepatocyte Proliferation During the Termination Phase of Liver Regeneration.	Hepatology Communications	2020
31005337	Hepatocyte transplantation, a step forward?	Journal of Hepatology	2019
30582979	Hepatocyte-specific suppression of microRNA-221-3p mitigates liver fibrosis.	Journal of Hepatology	2019
30536094	Conversion of Fibroblasts to Hepatocyte-Like Cells In Vivo.	Methods in Molecular Biology	2019
29520052	Expansion of functional personalized cells with specific transgene combinations.	Nat Commun	2018
30075026	Interferon-beta expression and type I interferon receptor signaling of hepatocytes prevent hepatic necrosis and virus dissemination in Coxsackievirus B3-infected mice.	PLoS Pathogens	2018
29445149	Let-7c inhibits cholangiocarcinoma growth but promotes tumor cell invasion and growth at extrahepatic sites.	Cell Death Dis	2018
29527263	Homologous recombination mediates stable Fah gene integration and phenotypic correction in tyrosinaemia mouse-model.	World Journal of Hepatology	2018
27935144	A Bio-Chemosynthetic Approach to Superparamagnetic Iron Oxide-Ansamitocin Conjugates for Use in Magnetic Drug Targeting.	Chemistry - A European Journal	2017
28585348	Synthesis of Magnetic-Nanoparticle/Ansamitocin Conjugates-Inductive Heating Leads to Decreased Cell Proliferation In Vitro and Attenuation Of Tumour Growth In Vivo.	Chemistry - A European Journal	2017
28699415	A Scalable Approach for the Generation of Human Pluripotent Stem Cell-Derived Hepatic Organoids with Sensitive Hepatotoxicity Features.		2017
29031907	About cytokeratin 19 and the drivers of liver regeneration.	Journal of Hepatology	2017
27138041	Generation of Genetically Engineered Precursor T-Cells From Human Umbilical Cord Blood Using an Optimized Alpharetroviral Vector Platform.	Mol Ther	2016
27336362	MicroRNA-125b-5p mimic inhibits acute liver failure.	Nature Communications	2016
26923201	Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes InÂ Vivo Attenuates Liver Fibrosis.	Cell Stem Cell	2016
25135862	MicroRNA-199a-5p inhibition enhances the liver repopulation ability of human embryonic stem cell-derived hepatic cells.	J Hepatol	2015
25594875	Adeno-associated virus vector-based gene therapy for monogenetic metabolic diseases of the liver.	Journal of Pediatric Gastroenterology and Nutrition	2015
25609814	Control of hepatitis C virus replication in mouse liver-derived cells by MAVS-dependent production of type I and type III interferons.	Journal of Virology	2015
25524146	Concise review: cell therapies for hereditary metabolic liver diseases-concepts, clinical results, and future developments.	Stem Cells	2015
24504462	The temporal and hierarchical control of transcription factors-induced liver to pancreas transdifferentiation.	PLoS ONE	2014
25315763	[Diagnosis and therapies for acute liver failure: scientific developments].	Der Internist	2014
23903236	Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells.	Gut	2014
23582328	A Direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration.	Cell	2013
22821679	MicroRNA-221 overexpression accelerates hepatocyte proliferation during liver regeneration.	Hepatology	2013
23845962	De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis.	Nat Protoc	2013
24140631	Optimization of upcyteÂ® human hepatocytes for the in vitro micronucleus assay.	Mutation Research - Genetic Toxicology and Environmental Mutagenesis	2013
23884859	Specific gene delivery to liver sinusoidal and artery endothelial cells.	Blood	2013
23926210	Sustained knockdown of a disease-causing gene in patient-specific induced pluripotent stem cells using lentiviral vector-based gene therapy.	Stem Cells Transl Med	2013
23642065	Improved hepatic differentiation strategies for human induced pluripotent stem cells.	Current Molecular Medicine	2013
23523523	Stability and transmission of hepatitis C virus in different anesthetic agents.	American Journal of Infection Control	2013
23258554	Hepatic lentiviral gene transfer is associated with clonal selection, but not with tumor formation in serially transplanted rodents.	Hepatology	2013
21850050	Epidermal growth factor improves lentivirus vector gene transfer into primary mouse hepatocytes.	Gene Therapy	2012
22648521	Mesenchymal stromal cells (MSCs): science and f(r)iction.	Journal of Molecular Medicine	2012