Author details

Full Name

Bruce D Pascal

Affiliation

The Scripps Research Institute

ORCID

Career Start Year

2006

Papers

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
35437807	The intrinsically disordered CARDs-Helicase linker in RIG-I is a molecular gate for RNA proofreading.	EMBO J	2022
34452998	Dual-mechanism estrogen receptor inhibitors.	Proc Natl Acad Sci U S A	2021
34644557	Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.	Immunity	2021
32658454	Comparative Analysis of Cleavage Specificities of Immobilized Porcine Pepsin and Nepenthesin II under Hydrogen/Deuterium Exchange Conditions.	Anal Chem	2020
33870216	Integrative structural biology studies of HIV-1 reverse transcriptase binding to a high-affinity DNA aptamer.	Curr Res Struct Biol	2020
31618757	HP1 reshapes nucleosome core to promote phase separation of heterochromatin.	Nature	2019
31724102	A Decoupled Automation Platform for Hydrogen/Deuterium Exchange Mass Spectrometry Experiments.	J Am Soc Mass Spectrom	2019
31299203	Irisin Mediates Effects on Bone and Fat via Î±V Integrin Receptors.	Cell	2019
31351767	Protein dynamics and conformational changes explored by hydrogen/deuterium exchange mass spectrometry.	Curr Opin Struct Biol	2019
30560918	HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity.	Nat Commun	2018
30906767	Structural and Dynamic Elucidation of a Non-acid PPAR<i>Î³</i> Partial Agonist: SR1988.	Nucl Receptor Res	2018
30297415	Long noncoding RNA GM12371 acts as a transcriptional regulator of synapse function.	Proc Natl Acad Sci U S A	2018
30550785	Irisin Mediates Effects on Bone and Fat via Î±V Integrin Receptors.	Cell	2018
30540250	Structural organization of a major neuronal G protein regulator, the RGS7-GÎ²5-R7BP complex.	Elife	2018
27807976	A Residue-Resolved Bayesian Approach to Quantitative Interpretation of Hydrogen-Deuterium Exchange from Mass Spectrometry: Application to Characterizing Protein-Ligand Interactions.	J Phys Chem B	2017
29030554	HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions.	Nat Commun	2017
28970104	Nucleotide Binding to ARL2 in the TBCDâ¿¿ARL2â¿¿Î²-Tubulin Complex Drives Conformational Changes in Î²-Tubulin.	J Mol Biol	2017
27224086	Two-Site Evaluation of the Repeatability and Precision of an Automated Dual-Column Hydrogen/Deuterium Exchange Mass Spectrometry Platform.	Anal Chem	2016
27902448	RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum.	Sci Signal	2016
25763479	Differential isotopic enrichment to facilitate characterization of asymmetric multimeric proteins using hydrogen/deuterium exchange mass spectrometry.	Anal Chem	2015
26265041	Software Analysis of Uncorrelated MS1 Peaks for Discovery of Post-Translational Modifications.	J Am Soc Mass Spectrom	2015
26451138	Identification of Bexarotene as a PPARÎ³ Antagonist with HDX.	PPAR Res	2015
26398198	SERBP1 Is a Component of the Liver Receptor Homologue-1 Transcriptional Complex.	J Proteome Res	2015
26227798	Conformational states of the full-length glucagon receptor.	Nat Commun	2015
26200343	Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.	Nature	2015
24440037	The therapeutic potential of nuclear receptor modulators for treatment of metabolic disorders: PPARÎ³, RORs, and Rev-erbs.	Cell Metab	2014
25352669	New approach to capture and characterize synaptic proteome.	Proc Natl Acad Sci U S A	2014
25180755	Glucagon-like peptide-1 receptor ligand interactions: structural cross talk between ligands and the extracellular domain.	PLoS One	2014
24909783	Influence of domain interactions on conformational mobility of the progesterone receptor detected by hydrogen/deuterium exchange mass spectrometry.	Structure	2014
24560804	Nitric oxide-induced conformational changes in soluble guanylate cyclase.	Structure	2014
23290725	Protein conformation ensembles monitored by HDX reveal a structural rationale for abscisic acid signaling protein affinities and activities.	Structure	2013
24076403	Activation of AMP-activated protein kinase revealed by hydrogen/deuterium exchange mass spectrometry.	Structure	2013
23884631	Time window expansion for HDX analysis of an intrinsically disordered protein.	J Am Soc Mass Spectrom	2013
23636859	Decoding split and pool combinatorial libraries with electron-transfer dissociation tandem mass spectrometry.	J Am Soc Mass Spectrom	2013
22692830	HDX workbench: software for the analysis of H/D exchange MS data.	J Am Soc Mass Spectrom	2012
21478866	DNA binding alters coactivator interaction surfaces of the intact VDR-RXR complex.	Nat Struct Mol Biol	2011
21528013	Methods for the Analysis of High Precision Differential Hydrogen Deuterium Exchange Data.	Int J Mass Spectrom	2011
21329427	Differential hydrogen/deuterium exchange mass spectrometry analysis of protein-ligand interactions.	Expert Rev Proteomics	2011
20058880	Dynamics of the beta2-adrenergic G-protein coupled receptor revealed by hydrogen-deuterium exchange.	Anal Chem	2010
20947021	Hydrogen/deuterium exchange reveals distinct agonist/partial agonist receptor dynamics within vitamin D receptor/retinoid X receptor heterodimer.	Structure	2010
19135386	HD desktop: an integrated platform for the analysis and visualization of H/D exchange data.	J Am Soc Mass Spectrom	2009
19739677	Unique ligand binding patterns between estrogen receptor alpha and beta revealed by hydrogen-deuterium exchange.	Biochemistry	2009
17506883	The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data.	BMC Bioinformatics	2007
17916792	A two-stage differential hydrogen deuterium exchange method for the rapid characterization of protein/ligand interactions.	J Biomol Tech	2007
16478090	Probing protein ligand interactions by automated hydrogen/deuterium exchange mass spectrometry.	Anal Chem	2006
16783638	A comprehensive mouse IBD database for the efficient localization of quantitative trait loci.	Mamm Genome	2006

1 - 46 of 46

Daniel S Ziemianowicz

University of Calgary, Arnie Charbonneau Cancer Institute

Career Start Year 2014

Number of shared co-authors 3

Argyris Politis

King's College London

Career Start Year 2009

Number of shared co-authors 1

Richard A Scheltema

Utrecht Institute for Pharmaceutical Sciences, Utrecht University

Career Start Year 2008

Number of shared co-authors 3

Kathleen S Molnar

Department of Pharmaceutical Chemistry, University of California San Francisco

Career Start Year 2006

Number of shared co-authors 3

Tobias Madl

Gottfried Schatz Research Center, Medical University of Graz

Career Start Year 2005

Number of shared co-authors 1

Miklos Guttman

University of Washington

Career Start Year 2003

Number of shared co-authors 1

Erik J Soderblom

Center for Genomic and Computational Biology, Duke University

Career Start Year 2003

Number of shared co-authors 0

Alexander Leitner

ETH Zurich

Career Start Year 2001

Number of shared co-authors 6

Mark J S Kelly

Department of Pharmaceutical Chemistry, University of California San Francisco

Career Start Year 2000

Number of shared co-authors 3

Feixia Chu

University of New Hampshire

Career Start Year 1999

Number of shared co-authors 4

Evgeniy V Petrotchenko

Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University

Career Start Year 1998

Number of shared co-authors 2

Juri Rappsilber

Institute for Biotechnology, Technical University Berlin

Career Start Year 1998

Number of shared co-authors 6

Wenqing Shui

iHuman Institute, ShanghaiTech University

Career Start Year 1998

Number of shared co-authors 3

Suzanne Ackloo

University of Toronto

Career Start Year 1997

Number of shared co-authors 0

David C Schriemer

University of Calgary, 0 Hospital Drive NW

Career Start Year 1996

Number of shared co-authors 6

Daniel Nietlispach

University of Cambridge

Career Start Year 1996

Number of shared co-authors 1

Volker D??tsch

Institute for Biophysical Chemistry, Goethe-University

Career Start Year 1995

Number of shared co-authors 2

Albert J R Heck

Utrecht University

Career Start Year 1991

Number of shared co-authors 3

Petr Nov??k

Institute of Microbiology of the CAS

Career Start Year 1991

Number of shared co-authors 2

Michael Sattler

Technical University of Munich, Institute of Structural Biology

Career Start Year 1991

Number of shared co-authors 1

Karl Mechtler

IMP-Institute of Molecular Pathology

Career Start Year 1990

Number of shared co-authors 2

Julie D Forman-Kay

Hospital for Sick Children

Career Start Year 1989

Number of shared co-authors 1

Cheryl H Arrowsmith

University of Toronto

Career Start Year 1989

Number of shared co-authors 2

Hartmut Oschkinat

Leibniz-Forschungsinstitut fur Molekulare Pharmakologie

Career Start Year 1988

Number of shared co-authors 1

Geerten W Vuister

Leicester Institute of Structural and Chemical Biology, University of Leicester

Career Start Year 1988

Number of shared co-authors 4

Ernest D Laue

University of Cambridge

Career Start Year 1987

Number of shared co-authors 1

Paul C Driscoll

The Francis Crick Institute

Career Start Year 1987

Number of shared co-authors 1

Mark R Chance

Case Western Reserve University

Career Start Year 1986

Number of shared co-authors 2

Michael L Gross

Washington University in St. Louis

Career Start Year 1978

Number of shared co-authors 0

David Cowburn

Albert Einstein College of Medicine

Career Start Year 1969

Number of shared co-authors 1

row(s) 1 - 30 of 30

Patrick R Griffin

The Scripps Research Institute

Co-authored papers 41

Michael J Chalmers

Lilly Research Laboratories

Co-authored papers 21

Jeffrey A Dodge

Lilly Research Laboratories

Co-authored papers 8

Timothy S Strutzenberg

Salk Institute for Biological Studies

Co-authored papers 4

Raymond C Stevens

iHuman Institute, ShanghaiTech University

Co-authored papers 3

David Marciano

Stanford Cardiovascular Institute (L.W., Stanford University School of Medicine

Co-authored papers 3

Howard Broughton

Lilly Research Laboratories

Co-authored papers 3

Alfonso Espada

Co-authored papers 3

Lynda F Bonewald

Indiana Center for Musculoskeletal Health, Indiana University School of Medicine

Co-authored papers 2

Xin-An Liu

Co-authored papers 2

Bridget Carragher

Columbia University

Co-authored papers 2

Clifford J Rosen

Maine Medical Center Research Institute

Co-authored papers 2

Hualiang Jiang

Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Co-authored papers 2

Christopher C Mader

Co-authored papers 2

Daniel J Saltzberg

University of California san francisco

Co-authored papers 1

Andrej Sali (CM4AI)

University of California San Francisco

Co-authored papers 1

Christopher L Hendrickson

Florida State University

Co-authored papers 1

Christine Humblet

Lilly Research Laboratories

Co-authored papers 1

Gye Won Han

Bridge Institute, University of Southern California

Co-authored papers 1

Riccardo Pellarin

CNRS UMR 5086 and Universite Claude Bernard Lyon 1

Co-authored papers 1

Theodore M Kamenecka

Co-authored papers 1

John D Gross

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 1

Mohammad Fallahi

Co-authored papers 1

Geeta J Narlikar

University of California san francisco

Co-authored papers 1

Qingping Xu

Argonne National Laboratory

Co-authored papers 1

Petra Fromme

Biodesign Center for Applied Structural Discovery, Arizona State University

Co-authored papers 1

Michael J Trnka

Department of Pharmaceutical Chemistry, University of California San Francisco

Co-authored papers 1

Alma L Burlingame

Department of Pharmaceutical Chemistry, University of California san francisco

Co-authored papers 1

1 - 28

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