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Full Name
Matthew C Altman
Affiliation
University of Washington School of Medicine, Seattle Benaroya Research Institute
ORCID
Career Start Year
2007
Papers
58
H Index
19
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36223848
Effects of combination treatment with tezepelumab and allergen immunotherapy on nasal responses to allergen: AÂ randomized controlled trial.
J Allergy Clin Immunol
2023
37460024
Nasal and blood transcriptomic pathways underpinning the clinical response to grass pollen immunotherapy.
J Allergy Clin Immunol
2023
37212596
Distinct Epithelial-Innate Immune Cell Transcriptional Circuits Underlie Airway Hyperresponsiveness in Asthma.
Am J Respir Crit Care Med
2023
37140544
Kimma: flexible linear mixed effects modeling with kinship covariance for RNA-seq data.
Bioinformatics
2023
37001649
Type 2 inflammation reduces SARS-CoV-2 replication in the airway epithelium in allergic asthma through functional alteration of ciliated epithelial cells.
J Allergy Clin Immunol
2023
37327781
Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients.
Cell Rep Med
2023
36649800
What Have Mechanistic Studies Taught Us About Childhood Asthma?
J Allergy Clin Immunol Pract
2023
36608946
Associations between outdoor air pollutants and non-viral asthma exacerbations and airway inflammatory responses in children and adolescents living in urban areas in the USA: a retrospective secondary analysis.
Lancet Planet Health
2023
36708815
Rhinovirus infection of the airway epithelium enhances mast cell immune responses via epithelial-derived interferons.
J Allergy Clin Immunol
2023
36638096
Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings.
PLoS Genet
2023
36754293
A functional genomics pipeline to identify high-value asthma and allergy CpGs in the human methylome.
J Allergy Clin Immunol
2023
34862819
17q12-q21 variants interact with early-life exposures to modify asthma risk in Black children.
Clin Exp Allergy
2022
35381269
Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB.
J Allergy Clin Immunol
2022
35606880
Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region.
Genome Med
2022
35666868
DNA methylation signatures in airway cells from adult children of asthmatic mothers reflect subtypes of severe asthma.
Proc Natl Acad Sci U S A
2022
35413355
Eosinophil-mediated suppression and anti-IL-5 enhancement of plasmacytoid dendritic cell interferon responses in asthma.
J Allergy Clin Immunol
2022
35964610
Mepolizumab for urban children with exacerbation-prone eosinophilic asthma in the USA (MUPPITS-2): a randomised, double-blind, placebo-controlled, parallel-group trial.
Lancet
2022
35149044
Seasonal airway microbiome and transcriptome interactions promote childhood asthma exacerbations.
J Allergy Clin Immunol
2022
35027395
Location of eosinophils in the airway wall is critical for specific features of airway hyperresponsiveness and T2 inflammation in asthma.
Eur Respir J
2022
33314187
Extracellular vesicle microRNAs as predictors of response to omalizumab in chronic spontaneous urticaria.
Allergy
2021
33683705
A consequentialist argument for considering age in triage decisions during the coronavirus pandemic.
Bioethics
2021
33713771
Endotype of allergic asthma with airway obstruction in urban children.
J Allergy Clin Immunol
2021
33624743
BloodGen3Module: blood transcriptional module repertoire analysis and visualization using R.
Bioinformatics
2021
33712279
Cockroach-induced IL9, IL13, and IL31 expression and the development of allergic asthma in urban children.
J Allergy Clin Immunol
2021
34675193
Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region.
Nat Commun
2021
34519110
Unique basophil microRNA signature in chronic spontaneous urticaria patients who respond to omalizumab.
Clin Exp Allergy
2021
34691392
Heterogeneity of magnitude, allergen immunodominance, and cytokine polarization of cockroach allergen-specific T cell responses in allergic sensitized children.
Clin Transl Allergy
2021
34629083
Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus.
Genome Med
2021
34531561
Ignition sequence start: epithelial allergen sensing and regulation of the allergic inflammatory response.
Nat Immunol
2021
34019912
Inducible expression quantitative trait locus analysis of the MUC5AC gene in asthma in urban populations of children.
J Allergy Clin Immunol
2021
34246435
Management Strategies to Reduce Exacerbations in non-T2 Asthma.
J Allergy Clin Immunol Pract
2021
34282143
Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data.
Nat Commun
2021
32169380
Nasal allergen challenge and environmental exposure chamber challenge: AÂ randomized trial comparing clinical and biological responses to cat allergen.
J Allergy Clin Immunol
2020
31888785
A 71-year-old man with recurrent pulmonary mycobacterial avium complex infections and lymphopenia.
Allergy Asthma Proc
2020
33377660
Definition of erythroid cell-positive blood transcriptome phenotypes associated with severe respiratory syncytial virus infection.
Clin Transl Med
2020
32736569
A modular framework for the development of targeted Covid-19 blood transcript profiling panels.
J Transl Med
2020
32246831
Human airway epithelial cells express a functional IL-5 receptor.
Allergy
2020
30962590
Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children.
Nat Immunol
2019
31437129
Airway epithelium-shifted mast cell infiltration regulates asthmatic inflammation via IL-33 signaling.
J Clin Invest
2019
30979657
Reply.
J Allergy Clin Immunol
2019
29111217
Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations.
J Allergy Clin Immunol
2018
29945814
Reply.
J Allergy Clin Immunol
2018
29518416
Allergen-induced activation of natural killer cells represents an early-life immune response in the development of allergic asthma.
J Allergy Clin Immunol
2018
29377961
Shared and organism-specific host responses to childhood diarrheal diseases revealed by whole blood transcript profiling.
PLoS One
2018
29106997
Interferon response to respiratory syncytial virus by bronchial epithelium from children with asthma is inversely correlated with pulmonary function.
J Allergy Clin Immunol
2018
27986392
Solving Immunology?
Trends Immunol
2017
28279664
Combination omalizumab and mepolizumab therapy for refractory allergic bronchopulmonary aspergillosis.
J Allergy Clin Immunol Pract
2017
28322850
Absence of functional fetal regulatory T cells in humans causes in utero organ-specific autoimmunity.
J Allergy Clin Immunol
2017
28179497
Multicenter Systems Analysis of Human Blood Reveals Immature Neutrophils in Males and During Pregnancy.
J Immunol
2017
28504594
A Deep Dive into Asthma Transcriptomics. Lessons from U-BIOPRED.
Am J Respir Crit Care Med
2017
1 - 50 of 58
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