Author details

Full Name

Matthew J Watt

Affiliation

ORCID

Career Start Year

1995

Papers

199

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37493472	Exercise training induces depot-specific remodeling of protein secretion in skeletal muscle and adipose tissue of obese male mice.		2023
36580496	Liver-Secreted Hexosaminidase A Regulates Insulin-Like Growth Factor Signaling and Glucose Transport in Skeletal Muscle.		2023
36574015	Multi-substrate Metabolic Tracing Reveals Marked Heterogeneity and Dependency on Fatty Acid Metabolism in Human Prostate Cancer.	Mol Cancer Res	2023
36949095	Mouse strain-dependent variation in metabolic associated fatty liver disease (MAFLD): a comprehensive resource tool for pre-clinical studies.		2023
36629823	Investigating dual inhibition of ACC and CD36 for the treatment of nonalcoholic fatty liver disease in mice.		2023
36479639	Metabolic effects of lipectomy and of adipose tissue transplantation.		2023
35304603	Exerkines in health, resilience and disease.	Nat Rev Endocrinol	2022
35381388	Proteomic analysis reveals exercise training induced remodelling of hepatokine secretion and uncovers syndecan-4 as a regulator of hepatic lipid metabolism.	Molecular Metabolism	2022
35882232	Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function.	Cell Metab	2022
35915255	Reply to 'Lactate as a major myokine and exerkine'.	Nat Rev Endocrinol	2022
37954502	is Dispensable for Mitochondrial Bioenergetics Within White/Beige Adipose Tissue.		2022
36591531	Lipid droplets and ferroptosis as new players in brain cancer glioblastoma progression and therapeutic resistance.		2022
35273160	Deep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control.	Nature Communications	2022
34907601	Intergenerational effects of a paternal Western diet during adolescence on offspring gut microbiota, stress reactivity, and social behavior.	FASEB Journal	2022
35127483	Personalized Medicine for Prostate Cancer: Is Targeting Metabolism a Reality?	Front Oncol	2022
34545251	Mesenteric lymphatic dysfunction promotes insulin resistance and represents a potential treatment target in obesity.	Nature Metabolism	2021
33645252	GIP receptor deletion in mice confers resistance to high-fat diet-induced obesity via alterations in energy expenditure and adipose tissue lipid metabolism.	American Journal of Physiology - Endocrinology and Metabolism	2021
33746906	Ectodysplasin A Is Increased inÂ Non-Alcoholic Fatty Liver Disease, But Is Not Associated With Type 2 Diabetes.	Frontiers in Endocrinology	2021
34066295	Western Diet Induced Remodelling of the Tongue Proteome.	Proteomes	2021
34001905	Yap regulates skeletal muscle fatty acid oxidation and adiposity in metabolic disease.	Nature Communications	2021
33843278	Proteome analysis of human adipocytes identifies depot-specific heterogeneity at metabolic control points.	Am J Physiol Endocrinol Metab	2021
33887358	Hepatic lipidomic remodeling in severe obesity manifests with steatosis and does not evolve with non-alcoholic steatohepatitis.	Journal of Hepatology	2021
33359740	Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity.	Molecular Metabolism	2021
33289685	Circulating cathepsin S improves glycaemic control in mice.	Journal of Endocrinology	2021
33334871	Perilipin 5 S155 phosphorylation by PKA is required for the control of hepatic lipid metabolism and glycemic control.	Journal of Lipid Research	2021
34800307	Hexosaminidase A (HEXA) regulates hepatic sphingolipid and lipoprotein metabolism in mice.	FASEB Journal	2021
34910515	Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance.	Science advances	2021
32603261	Impact of human visceral and glutealfemoral adipose tissue transplant on glycemic control in a mouse model of diet-induced obesity.	Am J Physiol Endocrinol Metab	2020
32306181	Inter-organelle Communication in the Pathogenesis of Mitochondrial Dysfunction and Insulin Resistance.	Current Diabetes Reports	2020
32180560	A Neural basis for Octanoic acid regulation of energy balance.	Molecular Metabolism	2020
32883413	Epicardial Adipose Tissue Accumulation Confers Atrial Conduction Abnormality.	Journal of the American College of Cardiology	2020
32878981	SMOC1 is a glucose-responsive hepatokine and therapeutic target for glycemic control.	Sci Transl Med	2020
32535104	Molecular regulators of lipid metabolism in the intestine - Underestimated therapeutic targets for obesity?	Biochem Pharmacol	2020
32747791	Metabolic communication during exercise.	Nature Metabolism	2020
32519789	Early intervention exercise training does not delay prostate cancer progression in Pten<sup>-/-</sup> mice.	Prostate	2020
33002557	Long Chain Fatty Acids Differentially Regulate Sub-populations of Arcuate POMC and NPY Neurons.	Neuroscience	2020
31098621	The Liver as an Endocrine Organ-Linking NAFLD and Insulin Resistance.	Endocrine Reviews	2019
31757939	Deletion of intestinal Hdac3 remodels the lipidome of enterocytes and protects mice from diet-induced obesity.	Nat Commun	2019
30449681	Preclinical Models for Studying NASH-Driven HCC: How Useful Are They?		2019
30229460	Effect of Body Mass Index, Metabolic Health and Adipose Tissue Inflammation on the Severity of Non-alcoholic Fatty Liver Disease in Bariatric Surgical Patients: a Prospective Study.	Obesity Surgery	2019
30617219	Perilipin 5 Deletion in Hepatocytes Remodels Lipid Metabolism and Causes Hepatic Insulin Resistance in Mice.		2019
31042478	Identification of Metabolically Distinct Adipocyte Progenitor Cells in Human Adipose Tissues.	Cell Rep	2019
31519776	Unsuspected Protumorigenic Signaling Role for the Oncometabolite GABA in Advanced Prostate Cancer.	Cancer Res	2019
30758088	Exercise serum increases GLUT4 in human adipocytes.	Experimental Physiology	2019
30814737	An integrative systems genetic analysis of mammalian lipid metabolism.	Nature	2019
30728288	Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer.	Sci Transl Med	2019
30724128	Impact of Lipotoxicity on Tissue "Cross Talk" and Metabolic Regulation.	Physiology	2019
31203232	Dysferlin deficiency alters lipid metabolism and remodels the skeletal muscle lipidome in mice.	Journal of Lipid Research	2019
29188818	No evidence of white adipocyte browning after endurance exercise training in obese men.	International Journal of Obesity	2018
30598871	The Influence of Aerobic Exercise on Hippocampal Integrity and Function: Preliminary Findings of a Multi-Modal Imaging Analysis.		2018