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Author Details

Walter J Chazin
and Center for Structural Biology, Vanderbilt University
1982
293
72
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36810829Binding by calmodulin is coupled to transient unfolding of the third FF domain of Prp40A.Protein Sci2023
37595876Temporal modelling of the biofilm lifecycle (TMBL) establishes kinetic analysis of plate-based bacterial biofilm dynamics.J Microbiol Methods2023
37786681Structure of RADX and mechanism for regulation of RAD51 nucleofilaments.bioRxiv2023
37884206Flexibility and Distributive Synthesis Regulate RNA Priming and Handoff in Human DNA Polymerase α-Primase.J Mol Biol2023
37577606Flexibility and distributive synthesis regulate RNA priming and handoff in human DNA polymerase α-primase.bioRxiv2023
37776864Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection.Cell Host Microbe2023
37572935CRISPR-dependent Base Editing Screens Identify Separation of Function Mutants of RADX with Altered RAD51 Regulatory Activity.J Mol Biol2023
37769710Comparative analysis of the physical properties of murine and human S100A7: Insight into why zinc piracy is mediated by human but not murine S100A7.J Biol Chem2023
37425789XPA tumor variants lead to defects in NER that sensitize cells to cisplatin.bioRxiv2023
37425782Iron acquisition by a commensal bacterium modifies host nutritional immunity during <i>Salmonella</i> infection.bioRxiv2023
36993335A mechanistic model of primer synthesis from catalytic structures of DNA polymerase α-primase.bioRxiv2023
35076656Mechanism of action of nucleotide excision repair machinery.Biochem Soc Trans2022
35617695Modification of the 4Fe-4S Cluster Charge Transport Pathway Alters RNA Synthesis by Yeast DNA Primase.Biochemistry2022
35584702Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis.Cell2022
35454108A Structural Perspective on Calprotectin as a Ligand of Receptors Mediating Inflammation and Potential Drug Target.Biomolecules2022
35862777Mutagenesis of the Loop 3 α-Helix of Neisseria gonorrhoeae TdfJ Inhibits S100A7 Binding and Utilization.mBio2022
35687855An Active Learning Framework Improves Tumor Variant Interpretation.Cancer Res2022
35909964The Innate Immune Protein Calprotectin Interacts With and Encases Biofilm Communities of <i>Pseudomonas aeruginosa</i> and <i>Staphylococcus aureus</i>.Front Cell Infect Microbiol2022
35969784Two interaction surfaces between XPA and RPA organize the preincision complex in nucleotide excision repair.Proc Natl Acad Sci U S A2022
35995841Uropathogenic Escherichia coli subverts mitochondrial metabolism to enable intracellular bacterial pathogenesis in urinary tract infection.Nat Microbiol2022
35102276TdfH selectively binds metal-loaded tetrameric calprotectin for zinc import.Commun Biol2022
35156850Adherence Enables Neisseria gonorrhoeae to Overcome Zinc Limitation Imposed by Nutritional Immunity Proteins.Infect Immun2022
35072520Neutrophil-Associated Responses to Vibrio cholerae Infection in a Natural Host Model.Infect Immun2022
33453169RADX controls RAD51 filament dynamics to regulate replication fork stability.Mol Cell2021
34853318Siderophore-mediated zinc acquisition enhances enterobacterial colonization of the inflamed gut.Nat Commun2021
34517755Distinctive Roles of Two Acinetobactin Isomers in Challenging Host Nutritional Immunity.mBio2021
34516771Neutrophil extracellular traps enhance macrophage killing of bacterial pathogens.Sci Adv2021
34272328Heterogeneous nuclear ribonucleoprotein E1 binds polycytosine DNA and monitors genome integrity.Life Sci Alliance2021
34156100A fragment-based approach to discovery of Receptor for Advanced Glycation End products inhibitors.Proteins2021
34197737EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart.Mol Cell2021
34370507The Zinc Transporter ZnuABC Is Critical for the Virulence of Chromobacterium violaceum and Contributes to Diverse Zinc-Dependent Physiological Processes.Infect Immun2021
32457249Molecular Insight into TdfH-Mediated Zinc Piracy from Human Calprotectin by Neisseria gonorrhoeae.mBio2020
31925419A key interaction with RPA orients XPA in NER complexes.Nucleic Acids Res2020
32093079Calmodulin Mutations Associated with Heart Arrhythmia: A Status Report.Int J Mol Sci2020
33074099Identification of ubiquitin Ser57 kinases regulating the oxidative stress response in yeast.Elife2020
33007515Envisioning how the prototypic molecular machine TFIIH functions in transcription initiation and DNA repair.DNA Repair (Amst)2020
30784584An Acinetobacter baumannii, Zinc-Regulated Peptidase Maintains Cell Wall Integrity during Immune-Mediated Nutrient Sequestration.Cell Rep2019
31744916The Immune Protein Calprotectin Impacts Clostridioides difficile Metabolism through Zinc Limitation.mBio2019
31409229The anti-parasitic agent suramin and several of its analogues are inhibitors of the DNA binding protein Mcm10.Open Biol2019
31575763Arachidonic Acid Kills Staphylococcus aureus through a Lipid Peroxidation Mechanism.mBio2019
31454269Genetic Mosaicism in Calmodulinopathy.Circ Genom Precis Med2019
31369630The novel interaction between Neisseria gonorrhoeae TdfJ and human S100A7 allows gonococci to subvert host zinc restriction.PLoS Pathog2019
30710280S100 Proteins in the Innate Immune Response to Pathogens.Methods Mol Biol2019
30943376The Innate Immune Protein S100A9 Protects from T-Helper Cell Type 2-mediated Allergic Airway Inflammation.Am J Respir Cell Mol Biol2019
30905682Multi-metal Restriction by Calprotectin Impacts De Novo Flavin Biosynthesis in Acinetobacter baumannii.Cell Chem Biol2019
31050191A new approach to discovery of S100 protein heterodimers.FEBS J2019
29326975Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer.Sci Adv2018
30206620Antimicrobial action of calprotectin that does not involve metal withholding.Metallomics2018
30007036Calprotectin protects against experimental colonic inflammation in mice.Br J Pharmacol2018
30222779Disrupted structure and aberrant function of CHIP mediates the loss of motor and cognitive function in preclinical models of SCAR16.PLoS Genet2018
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Collaborators

Richard M Caprioli
Mass Spectrometry Research Center, Vanderbilt University
Co-authored papers 10
David A Case
Rutgers University
Co-authored papers 7
Aled M Edwards
University of Toronto
Co-authored papers 7
Craig W Vander Kooi
Co-authored papers 7
Alfred L George
Northwestern University Feinberg School of Medicine
Co-authored papers 6
Kurt W??thrich
iHuman Institute, ShanghaiTech University
Co-authored papers 6
John Christodoulou
University of Melbourne, The Royal Children's Hospital
Co-authored papers 5
Cheryl H Arrowsmith
University of Toronto
Co-authored papers 5
Melanie D Ohi
Co-authored papers 5
John A Tainer
The University of Texas MD Anderson Cancer Center
Co-authored papers 5
Mallika Sastry
Co-authored papers 3
Alexey Bochkarev
University of Toronto
Co-authored papers 3
Mary Kay Washington
Co-authored papers 3
Ivaylo Ivanov
Georgia State University, GA 30302 USA Center for Diagnostics and Therapeutics
Co-authored papers 3
Sirano Dhe-Paganon
Dana-Farber Cancer Institute
Co-authored papers 2
Jonathan C Trinidad
Indiana University
Co-authored papers 2
Thomas Meitinger
Technical University of Munich, Institute of Human Genetics
Co-authored papers 2
Michael J Ackerman
Mayo Clinic, Windland Smith Rice Genetic Heart Rhythm Clinic)
Co-authored papers 2
James S Fraser
University of California san francisco
Co-authored papers 2
Kevin D Corbett
Co-authored papers 2
Peter Lichtner
Co-authored papers 2
Michael K Rosen
UT Southwestern Medical Center
Co-authored papers 2
Michal Hammel
Lawrence Berkeley National Laboratory
Co-authored papers 2
Matthew W Semler
Vanderbilt University Medical Center
Co-authored papers 2
Alexandre M J J Bonvin
Bijvoet Center for Biomolecular Research, Utrecht University
Co-authored papers 2
Veronique Vitart
Co-authored papers 2
Donald M Bers
Co-authored papers 2
John A Capra
Bakar Computational Health Sciences Institute, University of California san francisco
Co-authored papers 2
T Hofmann
University of Toronto
Co-authored papers 2
Yingtao Bi
Foundational Immunology, AbbVie Cambridge Research Center
Co-authored papers 1
Release 1.2