Author details

Full Name

Alexander Dilthey

Affiliation

ORCID

Career Start Year

2010

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37375093	Characterisation of Type II DNA Methyltransferases of .		2023
37333848	The role of microbiome-host interactions in the development of AlzheimerÂ´s disease.		2023
37129842	An appeal for strengthening genomic pathogen surveillance to improve pandemic preparedness and infection prevention: the German perspective.		2023
35253846	RNA transcription and degradation of Alu retrotransposons depends on sequence features and evolutionary history.	G3: Genes, Genomes, Genetics	2022
35773532	Emu: species-level microbial community profiling of full-length 16S rRNA Oxford Nanopore sequencing data.	Nature Methods	2022
36305336	Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021.	Eurosurveillance	2022
35410384	Pangenome-based genome inference allows efficient and accurate genotyping across a wide spectrum of variant classes.	Nat Genet	2022
34851165	Recombination Events among Colistin-Susceptible and -Resistant Acinetobacter baumannii Clinical Isolates Belonging to International Clone 7.	mSphere	2021
34281604	Haploflow: strain-resolved de novo assembly of viral genomes.	Genome Biol	2021
33532769	Haploflow: Strain-resolved <i>de novo</i> assembly of viral genomes.	bioRxiv	2021
34278371	Emergence of the E484K mutation in SARS-COV-2-infected immunocompromised patients treated with bamlanivimab in Germany.	Lancet Regional Health - Europe, The	2021
34136105	Modifying splice site usage with : Maintaining the while changing the underlying .	Computational and Structural Biotechnology Journal	2021
33189874	State-of-the-art genome inference in the human MHC.	International Journal of Biochemistry and Cell Biology	2021
32737300	Distinct genetic architectures and environmental factors associate with host response to the Î³2-herpesvirus infections.	Nat Commun	2020
32171299	Ultraplexing: increasing the efficiency of long-read sequencing for hybrid assembly with k-mer-based multiplexing.		2020
32876341	SARS-CoV-2 targets neurons of 3D human brain organoids.	EMBO J	2020
32750130	Development and validation of a universal blood donor genotyping platform: a multinational prospective study.	Blood Adv	2020
32524946	Genetic structure of SARS-CoV-2 reflects clonal superspreading and multiple independent introduction events, North-Rhine Westphalia, Germany, February and March 2020.	Eurosurveillance	2020
33292499	Characterisation of mobile genetic elements in Mycoplasma hominis with the description of ICEHo-II, a variant mycoplasma integrative and conjugative element.	Mobile DNA	2020
31375628	Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk.	Proc Natl Acad Sci U S A	2019
30942877	HLA*LA-HLA typing from linearly projected graph alignments.	Bioinformatics	2019
31296857	Strain-level metagenomic assignment and compositional estimation for long reads with MetaMaps.	Nat Commun	2019
29453219	European families reveal MHC class I and II associations with autoimmune-mediated congenital heart block.	Ann Rheum Dis	2018
29921915	DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis.	Nat Commun	2018
30346939	De novo assembly of haplotype-resolved genomes with trio binning.	Nat Biotechnol	2018
30423094	A fast adaptive algorithm for computing whole-genome homology maps.	Bioinformatics	2018
30085094	Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans.	Hum Mol Genet	2018
29708767	A Fast Approximate Algorithm for Mapping Long Reads to Large Reference Databases.	J Comput Biol	2018
29431738	Nanopore sequencing and assembly of a human genome with ultra-long reads.	Nat Biotechnol	2018
29788454	Variation in human chromosome 21 ribosomal RNA genes characterized by TAR cloning and long-read sequencing.	Nucleic Acids Res	2018
29075515	Characterisation of the changing genomic landscape of metastatic melanoma using cell free DNA.	NPJ Genom Med	2017
28759005	Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank.	Nat Genet	2017
27792722	High-Accuracy HLA Type Inference from Whole-Genome Sequencing Data Using Population Reference Graphs.	PLoS Comput Biol	2016
25987243	Comprehensive genome-wide evaluation of lapatinib-induced liver injury yields a single genetic signal centered on known risk allele HLA-DRB1*07:01.	Pharmacogenomics J	2016
26690249	Horizontally transferred genes cluster spatially and metabolically.	Biol Direct	2015
25915597	Improved genome inference in the MHC using a population reference graph.	Nat Genet	2015
26430804	Imputation of KIR Types from SNP Variation Data.	Am J Hum Genet	2015
26343388	Class II HLA interactions modulate genetic risk for multiple sclerosis.	Nat Genet	2015
23459081	Multi-population classical HLA type imputation.	PLoS Comput Biol	2013
24076602	Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.	Nat Genet	2013
22446964	Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles.	Nat Genet	2012
22577363	Psoriasis patients are enriched for genetic variants that protect against HIV-1 disease.	PLoS Genet	2012
21596858	Multiple Hodgkin lymphoma-associated loci within the HLA region at chromosome 6p21.3.	Blood	2011
21833088	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	Nature	2011
21059899	MHC variation and risk of childhood B-cell precursor acute lymphoblastic leukemia.	Blood	2011
21300701	HLA*IMP--an integrated framework for imputing classical HLA alleles from SNP genotypes.	Bioinformatics	2011
20953190	A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.	Nat Genet	2010