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Author Details

St??phanie Bou??
Philip Morris International Research Laboratories Pte. Ltd
2002
57
30
Dexter Pratt (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37072468Results and lessons learned from the sbv IMPROVER metagenomics diagnostics for inflammatory bowel disease challenge.Sci Rep2023
36042406Crowdsourced benchmarking of taxonomic metagenome profilers: lessons learned from the sbv IMPROVER Microbiomics challenge.BMC Genomics2022
32780830Reduced Chronic Toxicity and Carcinogenicity in A/J Mice in Response to Life-Time Exposure to Aerosol From a Heated Tobacco Product Compared With Cigarette Smoke.Toxicol Sci2020
32995294Comparing the preclinical risk profile of inhalable candidate and potential candidate modified risk tobacco products: A bridging use case.Toxicol Rep2020
30878573Toxicological assessment of Tobacco Heating System 2.2: Findings from an independent peer review.Regul Toxicol Pharmacol2019
30282506Embracing Transparency Through Data Sharing.Int J Toxicol2018
29890228Interrogating the microbiome: experimental and computational considerations in support of study reproducibility.Drug Discov Today2018
30221212The sbv IMPROVER Systems Toxicology Computational Challenge: Identification of Human and Species-Independent Blood Response Markers as Predictors of Smoking Exposure and Cessation Status.Comput Toxicol2018
28085253Crowd-Sourced Verification of Computational Methods and Data in Systems Toxicology: A Case Study with a Heat-Not-Burn Candidate Modified Risk Tobacco Product.Chem Res Toxicol2017
28111298Aerosol from Tobacco Heating System 2.2 has reduced impact on mouse heart gene expression compared with cigarette smoke.Food Chem Toxicol2017
27027324Effects of cigarette smoke, cessation and switching to a candidate modified risk tobacco product on the liver in Apoe -/- mice--a systems toxicology analysis.Inhal Toxicol2016
26582801Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe-/- Mice-An Integrative Systems Toxicology Analysis.Toxicol Sci2016
26609137An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe-/- Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes.Toxicol Sci2016
27793746Evaluation of the Tobacco Heating System 2.2. Part 4: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects compared with cigarette smoke.Regul Toxicol Pharmacol2016
27657052Alterations in Serum Polyunsaturated Fatty Acids and Eicosanoids in Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD).Int J Mol Sci2016
27207171The Apoe(-/-) mouse model: a suitable model to study cardiovascular and respiratory diseases in the context of cigarette smoke exposure and harm reduction.J Transl Med2016
27504010Crowdsourcing and curation: perspectives from biology and natural language processing.Database (Oxford)2016
27225756An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe-/- Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes.Toxicol Sci2016
27429547Community-Reviewed Biological Network Models for Toxicology and Drug Discovery Applications.Gene Regul Syst Bio2016
26890252SETD7 Regulates the Differentiation of Human Embryonic Stem Cells.PLoS One2016
26731301Comprehensive systems biology analysis of a 7-month cigarette smoke inhalation study in C57BL/6 mice.Sci Data2016
25592588Reputation-based collaborative network biology.Pac Symp Biocomput2015
26295358Toxicity of aerosols of nicotine and pyruvic acid (separate and combined) in Sprague-Dawley rats in a 28-day OECD 412 inhalation study and assessment of systems toxicology.Inhal Toxicol2015
26135855Systems Biology Research into Cardiovascular Disease: Contributions of Lipidomics-based Approaches to Biomarker Discovery.Curr Drug Discov Technol2015
25843363A 7-month cigarette smoke inhalation study in C57BL/6 mice demonstrates reduced lung inflammation and emphysema following smoking cessation or aerosol exposure from a prototypic modified risk tobacco product.Food Chem Toxicol2015
25887162Causal biological network database: a comprehensive platform of causal biological network models focused on the pulmonary and vascular systems.Database (Oxford)2015
25962837Transcriptional profiling and targeted proteomics reveals common molecular changes associated with cigarette smoke-induced lung emphysema development in five susceptible mouse strains.Inflamm Res2015
25741927Impact assessment of repeated exposure of organotypic 3D bronchial and nasal tissue culture models to whole cigarette smoke.J Vis Exp2015
24965703A vascular biology network model focused on inflammatory processes to investigate atherogenesis and plaque instability.J Transl Med2014
25977767The species translation challenge-a systems biology perspective on human and rat bronchial epithelial cells.Sci Data2014
23545500Macrohistone variants preserve cell identity by preventing the gain of H3K4me2 during reprogramming to pluripotency.Cell Rep2013
24096154Cigarette smoke induces molecular responses in respiratory tissues of ApoE(-/-) mice that are progressively deactivated upon cessation.Toxicology2013
24151423On Crowd-verification of Biological Networks.Bioinform Biol Insights2013
23966112Strengths and limitations of microarray-based phenotype prediction: lessons learned from the IMPROVER Diagnostic Signature Challenge.Bioinformatics2013
23669247Cigarette-smoke-induced atherogenic lipid profiles in plasma and vascular tissue of apolipoprotein E-deficient mice are attenuated by smoking cessation.Atherosclerosis2013
23102783Modulation of atherogenic lipidome by cigarette smoke in apolipoprotein E-deficient mice.Atherosclerosis2012
21252997Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration.Nat Rev Mol Cell Biol2011
21775417Waves of early transcriptional activation and pluripotency program initiation during human preimplantation development.Development2011
21602794LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells.Nat Cell Biol2011
21346760Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome.Nature2011
21339765Methods for making induced pluripotent stem cells: reprogramming à la carte.Nat Rev Genet2011
20179605Transcriptomics approach to investigate zebrafish heart regeneration.J Cardiovasc Med (Hagerstown)2010
21040898Epigenetic mechanisms that regulate cell identity.Cell Stem Cell2010
20729629Rem2 GTPase controls proliferation and apoptosis of neurons during embryo development.Cell Cycle2010
20862250Analysis of human and mouse reprogramming of somatic cells to induced pluripotent stem cells. What is in the plate?PLoS One2010
19059335ASTD: The Alternative Splicing and Transcript Diversity database.Genomics2009
20333179Recent amplification and impact of MITEs on the genome of grapevine (Vitis vinifera L.).Genome Biol Evol2009
19796614Generation of induced pluripotent stem cells from human cord blood using OCT4 and SOX2.Cell Stem Cell2009
19178699Global analysis of alternative splicing regulation by insulin and wingless signaling in Drosophila cells.Genome Biol2009
17851451Homozygous PMS2 germline mutations in two families with early-onset haematological malignancy, brain tumours, HNPCC-associated tumours, and signs of neurofibromatosis type 1.Eur J Hum Genet2008
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Collaborators

Philip Morris International Research Laboratories Pte. Ltd
Co-authored papers 33
Vectura Fertin Pharma
Co-authored papers 33
Co-authored papers 17
Inc., Salk Institute for Biological Studies
Co-authored papers 12
university of california los angeles
Co-authored papers 8
University of Wurzburg
Co-authored papers 5
IBM T.J. Watson Research Center
Co-authored papers 3
Johns Hopkins Bayview Medical Center
Co-authored papers 3
IBM T.J. Watson Research Center
Co-authored papers 3
Co-authored papers 2
ProtATonce Ltd, National Technical University of Athens
Co-authored papers 2
Novo Nordisk Foundation Center for Protein Research, University of Copenhagen
Co-authored papers 2
Co-authored papers 2
T.J. Watson Research Center
Co-authored papers 2
Co-authored papers 1
Broad Institute of MIT and Harvard
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
University of Melbourne
Co-authored papers 1
UC San Diego
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
University of Luxembourg
Co-authored papers 1
University of California berkeley
Co-authored papers 1
Universitat Basel
Co-authored papers 1
Stowers Institute for Medical Research
Co-authored papers 1
Co-authored papers 1