Author details

Full Name

Katherine A Fitzgerald

Affiliation

ORCID

Career Start Year

1997

Papers

311

H Index

116

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36596869	Long non-coding RNAs: definitions, functions, challenges and recommendations.	Nat Rev Mol Cell Biol	2023
36445376	Regulation of Synovial Î³Î´ T Cell Ligand Expression by Mitochondrial Reactive Oxygen Species and Gasdermin-D.	Journal of Immunology	2023
37549268	Targeting STING oligomerization with small-molecule inhibitors.		2023
37023130	STING-dependent interferon signatures restrict osteoclast differentiation and bone loss in mice.		2023
36893269	Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection.	Proc Natl Acad Sci U S A	2023
36577072	The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2.		2023
37142792	ERADication of STING limits inflammation.		2023
37018072	PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K.Â pneumoniae infection.		2023
36638547	Type-1 interferon-dependent and -independent mechanisms in cyclic GMP-AMP synthase-stimulator of interferon genes-driven auto-inflammation.	Curr Opin Immunol	2023
36750685	A path towards personalized medicine for autoinflammatory and related diseases.		2023
36693106	Activation of the NLRP1 inflammasome in human keratinocytes by the dsDNA mimetic poly(dA:dT).		2023
36740513	TBK1 inhibition unleashes RIPK1, resensitizing tumors to immunotherapy.		2023
36852999	MLKL-Driven Inflammasome Activation and Caspase-8 Mediate Inflammatory Cell Death in Influenza A Virus Infection.		2023
37494932	The lncRNA HOXA11os regulates mitochondrial function in myeloid cells to maintain intestinal homeostasis.		2023
37547024	Expression of a STING Gain-of-function Mutation in Endothelial Cells Initiates Lymphocytic Infiltration of the Lungs.	bioRxiv	2023
35013241	Myeloid cell nuclear differentiation antigen controls the pathogen-stimulated type I interferon cascade in human monocytes by transcriptional regulation of IRF7.	Nat Commun	2022
35656967	Intracellular Sensing of DNA in Autoinflammation and Autoimmunity.	Arthritis and Rheumatology	2022
36172366	Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants.	Front Immunol	2022
35968955	Microbial Metabolites Orchestrate a Distinct Multi-Tiered Regulatory Network in the Intestinal Epithelium That Directs P-Glycoprotein Expression.	mBio	2022
36356199	Dual Inhibitors of Main Protease (M<sup>Pro</sup>) and Cathepsin L as Potent Antivirals against SARS-CoV2.	J Am Chem Soc	2022
35642634	Lymphocyte crosstalk is required for monocyte-intrinsic trained immunity to Plasmodium falciparum.	Journal of Clinical Investigation	2022
36287122	Flnc: Machine Learning Improves the Identification of Novel Long Noncoding RNAs from Stand-Alone RNA-Seq Data.	Noncoding RNA	2022
35696583	Radioresistant cells initiate lymphocyte-dependent lung inflammation and IFNÎ³-dependent mortality in STING gain-of-function mice.	Proc Natl Acad Sci U S A	2022
35947978	Hold your horses! Reining in your fastest pores with caspase-7.	Immunity	2022
35792863	Epithelial HNF4A shapes the intraepithelial lymphocyte compartment via direct regulation of immune signaling molecules.	Journal of Experimental Medicine	2022
35547851	CNBP restricts SARS-CoV2 by regulating IFN and disrupting RNA-protein condensates.	Res Sq	2022
35332329	Author Correction: DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation.	Nature Immunology	2022
35217585	REL and BHLHE40 Variants Are Associated with IL-12 and IL-10 Responses and Tuberculosis Risk.	J Immunol	2022
34838807	Apoptosis, Pyroptosis, and Necroptosis-Oh My! The Many Ways a Cell Can Die.	Journal of Molecular Biology	2022
34705862	UMP-CMP kinase 2 gene expression in macrophages is dependent on the IRF3-IFNAR signaling axis.	PLoS ONE	2021
33854495	cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE.	Front Immunol	2021
34168080	Cellular nucleic acid-binding protein is essential for type I interferon-mediated immunity to RNA virus infection.	Proceedings of the National Academy of Sciences of the United States of America	2021
33740387	Lung Epithelial Cell Transcriptional Regulation as a Factor in COVID-19-associated Coagulopathies.	American Journal of Respiratory Cell and Molecular Biology	2021
34051146	Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells.	Immunity	2021
34325468	AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma.	J Exp Med	2021
32580911	Long non-coding RNAs in antiviral immunity.	Seminars in Cell and Developmental Biology	2021
33393506	Overcoming innate immune barriers that impede AAV gene therapy vectors.	Journal of Clinical Investigation	2021
34747695	A genetic screen in macrophages identifies new regulators of IFNÎ³-inducible MHCII that contribute to T cell activation.	Elife	2021
34403657	Igniting the firestorm: The inflammasome in autoinflammatory syndromes.	Journal of Allergy and Clinical Immunology	2021
32943500	HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation.	Science	2020
32134203	Direct Binding to NLRP3 Pyrin Domain as a Novel Strategy to Prevent NLRP3-Driven Inflammation and Gouty Arthritis.	Arthritis and Rheumatology	2020
31836654	A Mitochondrial Micropeptide Is Required for Activation of the Nlrp3 Inflammasome.	Journal of Immunology	2020
31882517	TLR2 Dimerization Blockade Allows Generation of Homeostatic Intestinal Macrophages under Acute Colitis Challenge.	Journal of Immunology	2020
32164908	Toll-like Receptors and the Control of Immunity.	Cell	2020
33311506	The long non-coding RNA LUCAT1 is a negative feedback regulator of interferon responses in humans.	Nature Communications	2020
33203781	Ensuring vaccine safety.	Science	2020
32929083	Caspase-8 mediates inflammation and disease in rodent malaria.	Nature Communications	2020
32820063	Succination inactivates gasdermin D and blocks pyroptosis.	Science	2020
33144583	Author Correction: Caspase-8 mediates inflammation and disease in rodent malaria.	Nature Communications	2020
32574626	Inflammasomes.	Current Biology	2020