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Author Details

Michael C Bassik
Stanford University Medical Center
1997
114
50
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37957268Cell volume expansion and local contractility drive collective invasion of the basement membrane in breast cancer.Nat Mater2024
37957268Cell volume expansion and local contractility drive collective invasion of the basement membrane in breast cancer.Nat Mater2024
36217031Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome.Nat Biotechnol2023
36217031Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome.Nat Biotechnol2023
37856615Elucidating the cellular determinants of targeted membrane protein degradation by lysosome-targeting chimeras.Science2023
37758944Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment.Nature2023
38014075An encyclopedia of enhancer-gene regulatory interactions in the human genome.bioRxiv2023
37561850A genome-wide genetic screen uncovers determinants of human pigmentation.Science2023
37696852Single-molecule imaging reveals distinct elongation and frameshifting dynamics between frames of expanded RNA repeats in C9ORF72-ALS/FTD.Nat Commun2023
37348463High-throughput discovery and characterization of viral transcriptional effectors in human cells.Cell Syst2023
36652947A BORC-dependent molecular pathway for vesiculation of cell corpse phagolysosomes.Curr Biol2023
37085898CasKAS: direct profiling of genome-wide dCas9 and Cas9 specificity using ssDNA mapping.Genome Biol2023
37020022Large-scale mapping and mutagenesis of human transcriptional effector domains.Nature2023
37333226Monocytes use protrusive forces to generate migration paths in viscoelastic collagen-based extracellular matrices.bioRxiv2023
37460812Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes.Nat Chem2023
37075117An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation.Sci Adv2023
37164018Co-transcriptional genome surveillance by HUSH is coupled to termination machinery.Mol Cell2023
37494933Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation.Dev Cell2023
37543039High-throughput functional characterization of combinations of transcriptional activators and repressors.Cell Syst2023
37292735SLC12A9 is a lysosome-detoxifying ammonium - chloride co-transporter.bioRxiv2023
37758944Assembloid CRISPR screens reveal impact of disease genes in human neurodevelopment.Nature2023
37561850A genome-wide genetic screen uncovers determinants of human pigmentation.Science2023
38014075An encyclopedia of enhancer-gene regulatory interactions in the human genome.bioRxiv2023
37856615Elucidating the cellular determinants of targeted membrane protein degradation by lysosome-targeting chimeras.Science2023
37696852Single-molecule imaging reveals distinct elongation and frameshifting dynamics between frames of expanded RNA repeats in C9ORF72-ALS/FTD.Nat Commun2023
37543039High-throughput functional characterization of combinations of transcriptional activators and repressors.Cell Syst2023
37494933Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation.Dev Cell2023
37460812Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes.Nat Chem2023
37292735SLC12A9 is a lysosome-detoxifying ammonium - chloride co-transporter.bioRxiv2023
37085898CasKAS: direct profiling of genome-wide dCas9 and Cas9 specificity using ssDNA mapping.Genome Biol2023
37020022Large-scale mapping and mutagenesis of human transcriptional effector domains.Nature2023
37348463High-throughput discovery and characterization of viral transcriptional effectors in human cells.Cell Syst2023
37075117An SPNS1-dependent lysosomal lipid transport pathway that enables cell survival under choline limitation.Sci Adv2023
37333226Monocytes use protrusive forces to generate migration paths in viscoelastic collagen-based extracellular matrices.bioRxiv2023
37164018Co-transcriptional genome surveillance by HUSH is coupled to termination machinery.Mol Cell2023
36652947A BORC-dependent molecular pathway for vesiculation of cell corpse phagolysosomes.Curr Biol2023
35259016Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegeneration.Proc Natl Acad Sci U S A2022
36307435The N<sup>6</sup>-methyladenosine methyltransferase METTL16 enables erythropoiesis through safeguarding genome integrity.Nat Commun2022
36178190Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform.Elife2022
36240778Spatial epitope barcoding reveals clonal tumor patch behaviors.Cancer Cell2022
36174103Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi by macrophages.PLoS Pathog2022
36357390A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience.Nat Commun2022
35578021Pathogenic or benign?Nat Biotechnol2022
36288714Genome-wide CRISPR screen reveals v-ATPase as a drug target to lower levels of ALS protein ataxin-2.Cell Rep2022
35637349Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability.Nat Chem Biol2022
35794338Functional characterization of the PI3K/AKT/MTOR signaling pathway for targeted therapy in B-precursor acute lymphoblastic leukemia.Cancer Gene Ther2022
35259016Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegeneration.Proc Natl Acad Sci U S A2022
35578021Pathogenic or benign?Nat Biotechnol2022
35794338Functional characterization of the PI3K/AKT/MTOR signaling pathway for targeted therapy in B-precursor acute lymphoblastic leukemia.Cancer Gene Ther2022
35637349Ribosome stalling during selenoprotein translation exposes a ferroptosis vulnerability.Nat Chem Biol2022
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Collaborators

Institute for Neurodegenerative Diseases, University of California san francisco
Co-authored papers 14
Whitehead Institute for Biomedical Research
Co-authored papers 13
Stanford University.
Co-authored papers 9
Stanford University
Co-authored papers 7
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Co-authored papers 6
Co-authored papers 6
Stanford University
Co-authored papers 5
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Co-authored papers 5
Broad Institute of MIT and Harvard
Co-authored papers 4
Stanford University School of Medicine
Co-authored papers 4
Co-authored papers 4
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Co-authored papers 4
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Co-authored papers 4
Stanford University School of Medicine
Co-authored papers 4
Universidade da Coruna
Co-authored papers 4
Pritzker School of Medicine, University of Chicago
Co-authored papers 3
Stanford University
Co-authored papers 3
Co-authored papers 3
Regeneron Pharmaceuticals Inc.
Co-authored papers 3
Stanford University School of Medicine, Center for Clinical Sciences Research
Co-authored papers 3
Department of Pediatrics Stanford University Stanford California USA.
Co-authored papers 3
Co-authored papers 3
Arc Institute
Co-authored papers 3
University of California San Francisco
Co-authored papers 3
Stanford University
Co-authored papers 3
Addenbrooke's Hospital, University of Cambridge
Co-authored papers 3
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The Ohio State University Comprehensive Cancer Center
Co-authored papers 2
Mayo Clinic
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