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Author Details
Full Name
Susanne Gr??slund
Affiliation
Karolinska Institutet
ORCID
Career Start Year
1999
Papers
51
H Index
25
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37572295
Autoantibodies against the melanoma differentiation-associated protein 5 in patients with dermatomyositis target the helicase domains.
Rheumatology (Oxford)
2024
36470210
Autoantigenic properties of the aminoacyl tRNA synthetase family in idiopathic inflammatory myopathies.
J Autoimmun
2023
35022656
Autoantibodies against four-and-a-half-LIM domain 1 (FHL1) in inflammatory myopathies: results from an Australian single-centre cohort.
Rheumatology (Oxford)
2022
35236390
Longitudinal assessment of reactivity and affinity profile of anti-Jo1 autoantibodies to distinct HisRS domains and a splice variant in a cohort of patients with myositis and anti-synthetase syndrome.
Arthritis Res Ther
2022
33125644
Screening and Production of Recombinant Human Proteins: Protein Production in E. coli.
Methods Mol Biol
2021
34233201
Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.
Structure
2021
32817337
Generation and validation of recombinant antibodies to study human aminoacyl-tRNA synthetases.
J Biol Chem
2020
31156624
Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients.
Front Immunol
2019
30560888
Patients with anti-Jo1 antibodies display a characteristic IgG Fc-glycan profile which is further enhanced in anti-Jo1 autoantibodies.
Sci Rep
2018
29856130
A DNA-Encoded Library of Chemical Compounds Based on Common Scaffolding Structures Reveals the Impact of Ligand Geometry on Protein Recognition.
ChemMedChem
2018
28470616
In Vivo Biotinylation of Antigens in E. coli.
Methods Mol Biol
2017
28255880
Antibody Validation by Immunoprecipitation Followed by Mass Spectrometry Analysis.
Methods Mol Biol
2017
26878383
Apollo-NADP(+): a spectrally tunable family of genetically encoded sensors for NADP(+).
Nat Methods
2016
25564516
Lysine demethylase KDM4A associates with translation machinery and regulates protein synthesis.
Cancer Discov
2015
26437402
Streamlining the Pipeline for Generation of Recombinant Affinity Reagents by Integrating the Affinity Maturation Step.
Int J Mol Sci
2015
26437229
Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins.
PLoS One
2015
26290498
A High Through-put Platform for Recombinant Antibodies to Folded Proteins.
Mol Cell Proteomics
2015
26121405
Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.
Nat Methods
2015
26121039
Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate.
PLoS One
2015
26061013
Tankyrase 1 Inhibitors with Drug-like Properties Identified by Screening a DNA-Encoded Chemical Library.
J Med Chem
2015
25650139
Identification of structure-activity relationships from screening a structurally compact DNA-encoded chemical library.
Angew Chem Int Ed Engl
2015
25530082
Recombinant renewable polyclonal antibodies.
MAbs
2015
24203325
Medium-throughput production of recombinant human proteins: protein production in E. coli.
Methods Mol Biol
2014
24981860
Human-chromatin-related protein interactions identify a demethylase complex required for chromosome segregation.
Cell Rep
2014
24595546
A Basic Post-SET Extension of NSDs Is Essential for Nucleosome Binding In Vitro.
J Biomol Screen
2014
24704254
Structural basis for phosphoinositide substrate recognition, catalysis, and membrane interactions in human inositol polyphosphate 5-phosphatases.
Structure
2014
23816837
Substrate specificity and oligomerization of human GMP synthetase.
J Mol Biol
2013
22027370
Expressing the human proteome for affinity proteomics: optimising expression of soluble protein domains and in vivo biotinylation.
N Biotechnol
2012
22662200
Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism.
PLoS One
2012
21308845
A secretory system for bacterial production of high-profile protein targets.
Protein Sci
2011
22180821
Recombinant protein quality evaluation: proposal for a minimal information standard.
Stand Genomic Sci
2011
21572409
A roadmap to generate renewable protein binders to the human proteome.
Nat Methods
2011
19883803
Towards proteome scale antibody selections using phage display.
N Biotechnol
2010
20164216
Generating a panel of highly specific antibodies to 20 human SH2 domains by phage display.
Protein Eng Des Sel
2010
18618707
The structure of the PP2A regulatory subunit B56 gamma: the remaining piece of the PP2A jigsaw puzzle.
Proteins
2009
19585659
Crystal structure of human diphosphoinositol phosphatase 1.
Proteins
2009
18171622
The use of systematic N- and C-terminal deletions to promote production and structural studies of recombinant proteins.
Protein Expr Purif
2008
18825127
A pilot project to generate affinity reagents to human proteins.
Nat Methods
2008
18767156
The crystal structure of human cleavage and polyadenylation specific factor-5 reveals a dimeric Nudix protein with a conserved catalytic site.
Proteins
2008
18235434
Protein production and purification.
Nat Methods
2008
18364358
Structural and biophysical characterization of human myo-inositol oxygenase.
J Biol Chem
2008
17138556
Crystal structure of human inosine triphosphatase. Substrate binding and implication of the inosine triphosphatase deficiency mutation P32T.
J Biol Chem
2007
17982461
In situ proteolysis for protein crystallization and structure determination.
Nat Methods
2007
17405878
Crystal structure of human cytosolic 5'-nucleotidase II: insights into allosteric regulation and substrate recognition.
J Biol Chem
2007
11916449
A high-stringency proteomics concept aimed for generation of antibodies specific for cDNA-encoded proteins.
Biotechnol Appl Biochem
2002
12204556
A novel affinity gene fusion system allowing protein A-based recovery of non-immunoglobulin gene products.
J Biotechnol
2002
12393214
Single-vector three-frame expression systems for affinity-tagged proteins.
FEMS Microbiol Lett
2002
11179667
Characterisation of the human APC1, the largest subunit of the anaphase-promoting complex.
Gene
2001
11089920
The spatial and temporal expression of Tekt1, a mouse tektin C homologue, during spermatogenesis suggest that it is involved in the development of the sperm tail basal body and axoneme.
Eur J Cell Biol
2000
10908795
High-throughput protein expression of cDNA products as a tool in functional genomics.
J Biotechnol
2000
1 - 50 of 51
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Collaborators
P??r Nordlund
Karolinska Institutet, BioClinicum J6
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Mathias Uhl??n
KTH Royal Institute of Technology
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Helena Persson
Lund University Cancer Centre
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Cheryl H Arrowsmith
University of Toronto
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P??l Stenmark
Stockholm University
Co-authored papers
4
Johan Weigelt
Karolinska Institutet
Co-authored papers
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University of Toronto
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4
Opher Gileadi
Structural Genomics Consortium Karolinska Institute Stockholm Sweden.
Co-authored papers
4
Jack F Greenblatt
College Street, University of Toronto
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3
B Martin Hallberg
Karolinska Institutet
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3
Sachdev S Sidhu
School of Pharmacy, University of Waterloo
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Peter Nilsson
Linkoping University
Co-authored papers
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Alexei Savchenko
University of Toronto
Co-authored papers
2
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College Street, University of Toronto
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Sadhna Phanse
University of Regina
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2
Youngchang Kim
Argonne National Laboratory
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2
Adelinda Yee
University of Toronto
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2
Raymond Hui
University of Toronto
Co-authored papers
2
Guoqing Zhong
University of Toronto
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2
Stephen Anderson
Center for Advanced Biotechnology and Medicine, Rutgers University
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