Author details

Full Name

David Lagares

Affiliation

Fibrosis Research Center, Massachusetts General Hospital, Harvard Medical School

ORCID

Career Start Year

2008

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36945535	Sanglifehrin A mitigates multi-organ fibrosis in vivo by inducing secretion of the collagen chaperone cyclophilin B.	bioRxiv	2023
37289107	Myocardin-related transcription factor contributes to renal fibrosis through the regulation of extracellular microenvironment surrounding fibroblasts.	FASEB J	2023
35983278	Recent Advances in Molecular Diagnosis of Pulmonary Fibrosis for Precision Medicine.	ACS Pharmacol Transl Sci	2022
34028739	Methods for Studying Myofibroblast Apoptotic Pathways.	Methods Mol Biol	2021
37118624	Anti-aging therapy for pulmonary fibrosis.	Nat Aging	2021
33894177	Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators.	Am J Pathol	2021
33556298	RNA Sequencing Uncovers Antifibrotic Genes during Lung Fibrosis Resolution.	Am J Respir Cell Mol Biol	2021
33526513	Induction of ADAM10 by Radiation Therapy Drives Fibrosis, Resistance, and Epithelial-to-Mesenchyal Transition in Pancreatic Cancer.	Cancer Res	2021
34550870	A Novel Protective Role for Matrix Metalloproteinase-8 in the Pulmonary Vasculature.	Am J Respir Crit Care Med	2021
34117675	Myofibroblast fate plasticity in tissue repair and fibrosis: Deactivation, apoptosis, senescence and reprogramming.	Wound Repair Regen	2021
34028750	Animal and Human Models of Tissue Repair and Fibrosis: An Introduction.	Methods Mol Biol	2021
34028747	Method for Investigating Fibroblast Durotaxis.	Methods Mol Biol	2021
32437826	Mechano-therapeutics: Targeting Mechanical Signaling in Fibrosis and Tumor Stroma.	Pharmacol Ther	2020
32054932	Assessing the progression of systemic sclerosis by monitoring the tissue optic axis using PS-OCT.	Sci Rep	2020
31792399	Evasion of apoptosis by myofibroblasts: a hallmark of fibrotic diseases.	Nat Rev Rheumatol	2020
31879264	Senotherapeutics: Targeting senescence in idiopathic pulmonary fibrosis.	Semin Cell Dev Biol	2020
32612176	A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction.	Nat Commun	2020
30277809	P311 in Scar Wars: Myofibroblasts Lost without Transforming Growth Factor Î² Translation.	Am J Respir Cell Mol Biol	2019
30980212	Ephrins and Eph Receptor Signaling in Tissue Repair and Fibrosis.	Curr Rheumatol Rep	2019
29349703	Matrix Stiffness: the Conductor of Organ Fibrosis.	Curr Rheumatol Rep	2018
29408011	BH3 mimetics as anti-fibrotic therapy: Unleashing the mitochondrial pathway of apoptosis in myofibroblasts.	Matrix Biol	2018
29211497	The Rho Kinase Isoforms ROCK1 and ROCK2 Each Contribute to the Development of Experimental Pulmonary Fibrosis.	Am J Respir Cell Mol Biol	2018
27927603	Lysophosphatidic acid signaling through its receptor initiates profibrotic epithelial cell fibroblast communication mediated by epithelial cell derived connective tissue growth factor.	Kidney Int	2017
29058717	ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis.	Nat Med	2017
29216045	Corrigendum: ADAM10-mediated ephrin-B2 shedding promotes myofibroblast activation and organ fibrosis.	Nat Med	2017
29237758	Targeted apoptosis of myofibroblasts with the BH3 mimetic ABT-263 reverses established fibrosis.	Sci Transl Med	2017
27006447	Autotaxin activity increases locally following lung injury, but is not required for pulmonary lysophosphatidic acid production or fibrosis.	FASEB J	2016
26600305	Fibrogenic Lung Injury Induces Non-Cell-Autonomous Fibroblast Invasion.	Am J Respir Cell Mol Biol	2016
27082727	Lysophosphatidic Acid Signaling through the Lysophosphatidic Acid-1 Receptor Is Required for Alveolarization.	Am J Respir Cell Mol Biol	2016
24651621	Cartilage-specific deletion of mTOR upregulates autophagy and protects mice from osteoarthritis.	Ann Rheum Dis	2015
25502501	Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis.	Am J Physiol Lung Cell Mol Physiol	2015
25573665	PPARÎ³ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage.	Ann Rheum Dis	2015
25012164	A pathogenetic role for endothelin-1 in peritoneal dialysis-associated fibrosis.	J Am Soc Nephrol	2015
24752182	Fibrosis--a lethal component of systemic sclerosis.	Nat Rev Rheumatol	2014
23329396	Targeting focal adhesion kinase in fibrotic diseases.	BioDrugs	2013
23572561	LOXL4 is induced by transforming growth factor Î²1 through Smad and JunB/Fra2 and contributes to vascular matrix remodeling.	Mol Cell Biol	2013
22492165	Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation.	Arthritis Rheum	2012
22962065	Adenoviral gene transfer of endothelin-1 in the lung induces pulmonary fibrosis through the activation of focal adhesion kinase.	Am J Respir Cell Mol Biol	2012
21296157	Role of endothelin in the cardiovascular system.	Pharmacol Res	2011
20131241	Endothelin 1 contributes to the effect of transforming growth factor beta1 on wound repair and skin fibrosis.	Arthritis Rheum	2010
18296102	Choline kinase as a link connecting phospholipid metabolism and cell cycle regulation: implications in cancer therapy.	Int J Biochem Cell Biol	2008
18809573	Glyceraldehyde-3-phosphate dehydrogenase regulates endothelin-1 expression by a novel, redox-sensitive mechanism involving mRNA stability.	Mol Cell Biol	2008

1 - 42 of 42

Kate M Herum

KG Jebsen Center for Cardiac Research, University of Oslo

Career Start Year 2013

Number of shared co-authors 0

Aditya Kumar

Rice University, University of California San Diego

Career Start Year 2013

Number of shared co-authors 0

Dikshya Bastakoty

Vanderbilt University

Career Start Year 2011

Number of shared co-authors 0

Zhipeng Meng

University of Miami Miller School of Medicine

Career Start Year 2009

Number of shared co-authors 0

Wanxia Li Tsai

National Institute of Arthritis

Career Start Year 2005

Number of shared co-authors 0

Anandaroop Mukhopadhyay

National University Hospital

Career Start Year 2005

Number of shared co-authors 0

Danny Jonigk

Institut fur Pathologie

Career Start Year 2004

Number of shared co-authors 0

Yingze Zhang

University of Pittsburgh

Career Start Year 2003

Number of shared co-authors 0

Tien Peng

Department of Medicine Cardiovascular Institute and Division of Pulmonary

Career Start Year 2003

Number of shared co-authors 0

Ana Guti??rrez-Fern??ndez

Instituto Universitario de Oncologia (IUOPA), Universidad de Oviedo

Career Start Year 2002

Number of shared co-authors 0

Alexander von Gise

Hannover Medical School

Career Start Year 2001

Number of shared co-authors 0

Kjetil Ask

McMaster University

Career Start Year 2001

Number of shared co-authors 0

Stefanie Krick

The University of Alabama at Birmingham

Career Start Year 2000

Number of shared co-authors 0

Gregory A Gibson

University of Pittsburgh

Career Start Year 1999

Number of shared co-authors 0

Chandra C Ghosh

The Wistar Institute

Career Start Year 1999

Number of shared co-authors 0

Sunil K Joshi

Knight Cancer Institute, Oregon Health & Science University

Career Start Year 1998

Number of shared co-authors 0

Bin Zhou

The Central Hospital of Shaoyang

Career Start Year 1998

Number of shared co-authors 0

Roya Navab

Princess Margaret Cancer Centre, University Health Network

Career Start Year 1997

Number of shared co-authors 0

Hyung J Chun

Yale Cardiovascular Research Center, Yale University School of Medicine

Career Start Year 1996

Number of shared co-authors 0

Maor Sauler

Yale School of Medicine

Career Start Year 1994

Number of shared co-authors 0

Erwin P Bottinger

Hasso Plattner Institute for Digital Health at Mount Sinai

Career Start Year 1992

Number of shared co-authors 0

John S Munger

School of Medicine and Langone Medical Center, New York University

Career Start Year 1991

Number of shared co-authors 0

Marie-Jos??e H??bert

Universite de Montreal

Career Start Year 1991

Number of shared co-authors 0

Susan E Crawford

NorthShore University HealthSystem, Research Institute, 1001 University Place

Career Start Year 1990

Number of shared co-authors 0

Fabio M V Rossi

University of British Columbia

Career Start Year 1990

Number of shared co-authors 0

Rainer Heuchel

Karolinska Institutet

Career Start Year 1988

Number of shared co-authors 1

Jeffrey L Wrana

Lunenfeld-Tanenbaum Research Institute Mount Sinai Hospital

Career Start Year 1985

Number of shared co-authors 0

Rama Khokha

Princess Margaret Cancer Centre, University Health Network

Career Start Year 1984

Number of shared co-authors 0

Kenneth Walsh

University of Virginia School of Medicine

Career Start Year 1982

Number of shared co-authors 0

Simon C Watkins

Center for Molecular Imaging, University of Pittsburgh School of Medicine

Career Start Year 1981

Number of shared co-authors 0

row(s) 1 - 30 of 30

Johanne Martel-Pelletier

Co-authored papers 4

Jean-Pierre Pelletier

Co-authored papers 4

Daniel J Tschumperlin

Mayo Clinic

Co-authored papers 3

Jerold Chun

Co-authored papers 2

Marco Del Chiaro

University of Colorado

Co-authored papers 1

Evgeny Berdyshev

National Jewish Health

Co-authored papers 1

Andy Phan

University of Colorado Anschutz Medical Campus

Co-authored papers 1

James C Costello

University of Colorado Anschutz Medical Campus

Co-authored papers 1

Shilpa Bhatia

University of Colorado Denver at Anschutz Medical Campus

Co-authored papers 1

Peter J Dempsey

University of Colorado

Co-authored papers 1

Michael J Gough

Earle A. Chiles Research Institute, Providence Cancer Institute

Co-authored papers 1

Antonio Galveo Neto

University of Colorado

Co-authored papers 1

Matthew R G Taylor

Cardiovascular Institute, University of Colorado

Co-authored papers 1

Michael W Knitz

University of Colorado

Co-authored papers 1

Kirk C Hansen

University of Colorado Anschutz Medical Campus

Co-authored papers 1

Cheryl Meguid

University of Colorado

Co-authored papers 1

Kimberly R Jordan

University of Colorado Anschutz Medical Campus

Co-authored papers 1

Karyn A Goodman

Mount Sinai Hospital

Co-authored papers 1

David J Abraham

Co-authored papers 1

Adrie van Bokhoven

University of Colorado Anschutz Medical Campus

Co-authored papers 1

Casey S Greene

Dartmouth College Geisel School of Medicine, Princeton University, University of Colorado Anschutz Medical Campus, University of Pennsylvania Perelman School of Medicine

Co-authored papers 1

Brisa Pe??a

Cardiovascular Institute, University of Colorado Denver Anschutz Medical Campus

Co-authored papers 1

Irina Bronova

National Jewish Health

Co-authored papers 1

Martin D McCarter

University of Colorado School of Medicine

Co-authored papers 1

Ayman Oweida

Universite de Sherbrooke