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Author Details

Robin Lovell-Badge
The Francis Crick Institute
1980
218
76
PMIDPaper TitleJournal TitlePublished Year
36122567A New Understanding, Guided by Single-Cell Sequencing, of the Establishment and Maintenance of the Ovarian Reserve in Mammals.Sex Dev2023
37792947SOX9-positive pituitary stem cells differ according to their position in the gland and maintenance of their progeny depends on context.Sci Adv2023
37183548Novel Candidate Regulators and Developmental Trajectory of Pituitary Thyrotropes.Endocrinology2023
36584300Hypomorphic and dominant-negative impact of truncated SOX9 dysregulates Hedgehog-Wnt signaling, causing campomelia.Proc Natl Acad Sci U S A2023
36627412The rates of adult neurogenesis and oligodendrogenesis are linked to cell cycle regulation through p27-dependent gene repression of SOX2.Cell Mol Life Sci2023
35205666SOX9 Triggers Different Epithelial to Mesenchymal Transition States to Promote Pancreatic Cancer Progression.Cancers (Basel)2022
35562901High SOX9 Maintains Glioma Stem Cell Activity through a Regulatory Loop Involving STAT3 and PML.Int J Mol Sci2022
35906245TRIM28-dependent SUMOylation protects the adult ovary from activation of the testicular pathway.Nat Commun2022
35966104The Properties and Functions of Glial Cell Types of the Hypothalamic Median Eminence.Front Endocrinol (Lausanne)2022
36067402The cortical hem lacks stem cell potential despite expressing SOX9 and HOPX.Dev Neurobiol2022
36343245SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms.Proc Natl Acad Sci U S A2022
33596732Applications of genome editing on laboratory animals.Lab Anim2022
33393905Dentate gyrus development requires a cortical hem-derived astrocytic scaffold.Elife2021
33574062SOX2 is required independently in both stem and differentiated cells for pituitary tumorigenesis in <i>p27</i>-null mice.Proc Natl Acad Sci U S A2021
33805518<i>CRISPR/Cas9</i> Deletion of <i>SOX2 Regulatory Region 2</i> (<i>SRR2</i>) Decreases SOX2 Malignant Activity in Glioblastoma.Cancers (Basel)2021
33888561Establishing and maintaining fertility: the importance of cell cycle arrest.Genes Dev2021
33658372Primary sex determination in birds depends on DMRT1 dosage, but gonadal sex does not determine adult secondary sex characteristics.Proc Natl Acad Sci U S A2021
34753143Long-Range Regulation of Key Sex Determination Genes.Sex Dev2021
33994951Novel Tools and Investigative Approaches for the Study of Oligodendrocyte Precursor Cells (NG2-Glia) in CNS Development and Disease.Front Cell Neurosci2021
34040207Stem-cell guidelines: why it was time for an update.Nature2021
34087160New guidelines for stem cell and embryo research from the ISSCR.Cell Stem Cell2021
34048692ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update.Stem Cell Reports2021
33973015Two alternative methods for the retrieval of somatic cell populations from the mouse ovary.Mol Hum Reprod2021
32317665SOX3 promotes generation of committed spermatogonia in postnatal mouse testes.Sci Rep2020
32001442Oestrogen in the chick embryo can induce chromosomally male ZZ left gonad epithelial cells to form an ovarian cortex that can support oogenesis.Development2020
33109617Paul S. Burgoyne (1946-2020).Development2020
32758351Signal transducer and activator of transcription (STAT) 1 and STAT3 are expressed in the human ovary and have Janus kinase 1-independent functions in the COV434 human granulosa cell line.Reprod Fertil Dev2020
32493750Testis formation in XX individuals resulting from novel pathogenic variants in Wilms' tumor 1 (<i>WT1</i>) gene.Proc Natl Acad Sci U S A2020
30594505Gonadal supporting cells acquire sex-specific chromatin landscapes during mammalian sex determination.Dev Biol2019
30728161CRISPR babies: a view from the centre of the storm.Development2019
30999977The regulation of Sox9 expression in the gonad.Curr Top Dev Biol2019
30649993After the Storm - A Responsible Path for Genome Editing.N Engl J Med2019
29406506Corrigendum: Assisted reproductive technologies to prevent human mitochondrial disease transmission.Nat Biotechnol2018
29903884Sex reversal following deletion of a single distal enhancer of <i>Sox9</i>.Science2018
29979654Corrigendum: Assisted reproductive technologies to prevent human mitochondrial disease transmission.Nat Biotechnol2018
30343898Nervous System Regionalization Entails Axial Allocation before Neural Differentiation.Cell2018
29578405NOTCH activity differentially affects alternative cell fate acquisition and maintenance.Elife2018
27530416Pivotal role of median eminence tanycytes for hypothalamic function and neurogenesis.Mol Cell Endocrinol2017
28146551Correction: Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone.PLoS Genet2017
29284798High expression of MKP1/DUSP1 counteracts glioma stem cell activity and mediates HDAC inhibitor response.Oncogenesis2017
28985523Human Embryo Editing: Opportunities and Importance of Transnational Cooperation.Cell Stem Cell2017
29121021Revisiting the Warnock rule.Nat Biotechnol2017
29121011Assisted reproductive technologies to prevent human mitochondrial disease transmission.Nat Biotechnol2017
29220028Erratum: Revisiting the Warnock rule.Nat Biotechnol2017
28045957Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone.PLoS Genet2017
26878385mTOR inhibition decreases SOX2-SOX9 mediated glioma stem cell activity and temozolomide resistance.Expert Opin Ther Targets2016
27557582RNA FISH, DNA FISH and Chromosome Painting of Chicken Oocytes.Methods Mol Biol2016
27529507Debate on Germline Gene Editing.Hum Gene Ther Methods2016
27226320SOX2 is sequentially required for progenitor proliferation and lineage specification in the developing pituitary.Development2016
27190031Of sex and determination: marking 25â¿¿years of Randy, the sex-reversed mouse.Development2016
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Collaborators

Co-authored papers 11
Center for Bioethics, Harvard Medical School
Co-authored papers 5
Great Ormond Street Hospital for Children NHS Foundation Trust
Co-authored papers 5
Carlsberg Laboratory, Case Western Reserve University, Johns Hopkins Medicine, Johns Hopkins School of Medicine, Johns Hopkins School of Public Health, Johns Hopkins University, National Academy of Sciences, Pennsylvania State University, Presidential Commission for the Study of Bioethical Issues
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Osaka University
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University of Manchester
Co-authored papers 4
MRC Harwell Institute
Co-authored papers 4
University of California irvine
Co-authored papers 4
University of Wisconsin-Madison/Nuclear Threat Initiative
Co-authored papers 3
Co-authored papers 3
Guys' and St Thomas' NHS Foundation Trust
Co-authored papers 3
The Hospital for Sick Children
Co-authored papers 3
Miller School of Medicine, University of Miami
Co-authored papers 3
UCSF Helen Diller Family Comprehensive Cancer Center
Co-authored papers 3
Vita-Salute San Raffaele University
Co-authored papers 3
California Institute of Technology, USA. institute of technology.edu.
Co-authored papers 2
University Paris-Sud, Universite Paris-Saclay (UPSay)
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University of Alberta
Co-authored papers 2
The Wellcome Trust Sanger Institute
Co-authored papers 2
the Francis Crick Institute
Co-authored papers 2
Exercise Medicine Research Institute, Edith Cowan University
Co-authored papers 2
Johns Hopkins Berman Institute of Bioethics
Co-authored papers 2
The Gurdon Institute
Co-authored papers 2
Faculty of Law and School of Public Health, University of Alberta
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University of Melbourne
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Gregorio Maranon University Hospital
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University of Regina
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Wyss Institute for Biologically Inspired Engineering, Harvard University
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