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Author Details

Kotaro Shirakawa
Graduate School of Medicine, Kyoto University
2004
51
25
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36972660HTLV-1 bZIP factor impairs DNA mismatch repair system.Biochem Biophys Res Commun2023
37796123Multiple mutations of SARS-CoV-2 Omicron BA.2 variant orchestrate its virological characteristics.J Virol2023
34968415The SARS-CoV-2 Lambda variant exhibits enhanced infectivity and immune resistance.Cell Rep2022
35794202A panel of nanobodies recognizing conserved hidden clefts of all SARS-CoV-2 spike variants including Omicron.Commun Biol2022
35568035Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike.Cell2022
36435945Intratracheal trimerized nanobody cocktail administration suppresses weight loss and prolongs survival of SARS-CoV-2 infected mice.Commun Med (Lond)2022
36507224The SARS-CoV-2 spike S375F mutation characterizes the Omicron BA.1 variant.iScience2022
36198317Virological characteristics of the SARS-CoV-2 Omicron BA.2 subvariants, including BA.4 and BA.5.Cell2022
36228744Pharmacologic characterization of TBP1901, a prodrug form of aglycone curcumin, and CRISPR-Cas9 screen for therapeutic targets of aglycone curcumin.Eur J Pharmacol2022
35176774Characterization of the Immune Resistance of Severe Acute Respiratory Syndrome Coronavirus 2 Mu Variant and the Robust Immunity Induced by Mu Infection.J Infect Dis2022
35145187ILF2 enhances the DNA cytosine deaminase activity of tumor mutator APOBEC3B in multiple myeloma cells.Sci Rep2022
34260717SARS-CoV-2 B.1.617 Mutations L452R and E484Q Are Not Synergistic for Antibody Evasion.J Infect Dis2021
33767685FRET-Based Detection and Quantification of HIV-1 Virion Maturation.Front Microbiol2021
33592502APOBEC3B is preferentially expressed at the G2/M phase of cell cycle.Biochem Biophys Res Commun2021
33504604CAGE-seq reveals that HIV-1 latent infection does not trigger unique cellular responses in a Jurkat T cell model.J Virol2021
34731554Neutralization of the SARS-CoV-2 Mu Variant by Convalescent and Vaccine Serum.N Engl J Med2021
32533515Alternative splicing of APOBEC3D generates functional diversity and its role as a DNA mutator.Int J Hematol2020
31914134APOBEC3B reporter myeloma cell lines identify DNA damage response pathways leading to APOBEC3B expression.PLoS One2020
32446377Critical role of PP2A-B56 family protein degradation in HIV-1 Vif mediated G2 cell cycle arrest.Biochem Biophys Res Commun2020
30935695A screening for DNA damage response molecules that affect HIV-1 infection.Biochem Biophys Res Commun2019
31477927NET-CAGE characterizes the dynamics and topology of human transcribed cis-regulatory elements.Nat Genet2019
31073151Endogenous APOBEC3B Overexpression Constitutively Generates DNA Substitutions and Deletions in Myeloma Cells.Sci Rep2019
31165764Protein kinase A inhibits tumor mutator APOBEC3B through phosphorylation.Sci Rep2019
31165049Structural Determinants of the APOBEC3G N-Terminal Domain for HIV-1 RNA Association.Front Cell Infect Microbiol2019
29077243Dual inhibition of the mTORC1 and mTORC2 signaling pathways is a promising therapeutic target for adult T-cell leukemia.Cancer Sci2018
29526961Choledochoduodenal Fistula during Chemotherapy with Brentuximab Vedotin for Methotrexate-associated Lymphoproliferative Disorder.Intern Med2018
28993637HTLV-1 bZIP factor suppresses TDP1 expression through inhibition of NRF-1 in adult T-cell leukemia.Sci Rep2017
26686024Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype.Cell Metab2016
27758855Core Binding Factor β Protects HIV, Type 1 Accessory Protein Viral Infectivity Factor from MDM2-mediated Degradation.J Biol Chem2016
27709813Expression of Tim-1 in primary CNS lymphoma.Cancer Med2016
27577680Classical NF-κB pathway is responsible for APOBEC3B expression in cancer cells.Biochem Biophys Res Commun2016
27244239Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity.Elife2016
25987725SIRT1 deacetylates RORγt and enhances Th17 cell generation.J Exp Med2015
26601161Abacavir, an anti-HIV-1 drug, targets TDP1-deficient adult T cell leukemia.Sci Adv2015
26390242Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.Nat Med2015
25918343SIRT1 deacetylates RORγt and enhances Th17 cell generation.J Exp Med2015
25876785[Successful treatment with recombinant thrombomodulin for disseminated intravascular coagulation complicated with hemophagocytic syndrome].Rinsho Ketsueki2015
23223453Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor.Science2013
24385908An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients.PLoS Pathog2013
23517573Reactivation of latent HIV by histone deacetylase inhibitors.Trends Microbiol2013
22372374HIV latency: experimental systems and molecular models.FEMS Microbiol Rev2012
21242889Epigenetic regulation of HIV latency.Curr Opin HIV AIDS2011
21071676HIV-1 viral infectivity factor interacts with TP53 to induce G2 cell cycle arrest and positively regulate viral replication.Proc Natl Acad Sci U S A2010
19128510MDM2 is a novel E3 ligase for HIV-1 Vif.Retrovirology2009
18336343Cytidine deaminases as a weapon against retroviruses and a new target for antiviral therapy.Mini Rev Med Chem2008
18836454Phosphorylation of APOBEC3G by protein kinase A regulates its interaction with HIV-1 Vif.Nat Struct Mol Biol2008
17251560Dual effect of APOBEC3G on Hepatitis B virus.J Gen Virol2007
16303161Ubiquitination of APOBEC3 proteins by the Vif-Cullin5-ElonginB-ElonginC complex.Virology2006
16890533Murine retrovirus escapes from murine APOBEC3 via two distinct novel mechanisms.Curr Biol2006
15943885APOBEC3G targets human T-cell leukemia virus type 1.Retrovirology2005
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Collaborators

Keisuke Shindo
Graduate School of Medicine, Kyoto University
Co-authored papers 12
Eric Verdin
Buck Institute for Research on Aging
Co-authored papers 11
Hyung W Lim
Gladstone Institute of Virology and Immunology
Co-authored papers 5
Gideon Schreiber
Co-authored papers 5
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The Buck Institute for Research on Aging
Co-authored papers 3
Melanie Ott
Gladstone Institute of Virology
Co-authored papers 3
Shweta Hakre
AstraZeneca Pharmaceuticals
Co-authored papers 3
Katerina Akassoglou
Gladstone Institute for Neurological Disease San Francisco
Co-authored papers 3
Kei Sato
The Institute of Medical Science, The University of Tokyo
Co-authored papers 3
Birgit Schilling
Buck Institute for Research on Aging
Co-authored papers 3
Herbert G Kasler
Buck Institute for Research on Aging
Co-authored papers 2
Jae K Ryu
Gladstone Institutes
Co-authored papers 2
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Center for Cancer Research, National Cancer Institute
Co-authored papers 2
Hideya Kawaji
RIKEN Center for Integrative Medical Sciences
Co-authored papers 2
Hye-Sook Kwon
Stanford University School of Medicine
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Mingjian Fei
Genentech Inc.
Co-authored papers 2
Christopher B Newgard
Duke Molecular Physiology Institute
Co-authored papers 1
Jason E Gestwicki
Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 1
Chao Wang
Gladstone Institutes
Co-authored papers 1
Lisa M Ellerby
Buck Institute for Research on Aging
Co-authored papers 1
Vinodh N Rajapakse
Co-authored papers 1
Peter Dongmin Sohn
Gladstone Institutes
Co-authored papers 1
Robert V Farese
Harvard T.H. Chan School of Public Health
Co-authored papers 1
Xu Chen
Gladstone Institutes
Co-authored papers 1
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 1
Yaqiao Li
Harvard Medical School
Co-authored papers 1
Piero Carninci
RIKEN Center for Integrative Medical Sciences
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Jonathan Chan
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