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Author Details

Sebastian Major
Center for Stroke Research Berlin, Charite - Universitatsmedizin Berlin
2004
50
28
PMIDPaper TitleJournal TitlePublished Year
36329390Stroke-prone salt-sensitive spontaneously hypertensive rats show higher susceptibility to spreading depolarization (SD) and altered hemodynamic responses to SD.J Cereb Blood Flow Metab2023
37746704Prediction of Stroke Outcome in Mice Based on Noninvasive MRI and Behavioral Testing.Stroke2023
37038498Spreading depolarization and angiographic spasm are separate mediators of delayed infarcts.Brain Commun2023
36742202Unveiling age-independent spectral markers of propofol-induced loss of consciousness by decomposing the electroencephalographic spectrum into its periodic and aperiodic components.Front Aging Neurosci2023
36686541Less-invasive subdural electrocorticography for investigation of spreading depolarizations in patients with subarachnoid hemorrhage.Front Neurol2023
34427143Physiological variables in association with spreading depolarizations in the late phase of ischemic stroke.J Cereb Blood Flow Metab2022
35411920Spreading depolarizations in ischaemia after subarachnoid haemorrhage, a diagnostic phase III study.Brain2022
35837483Increased Direct Current-Electroencephalography Shifts During Induction of Anesthesia in Elderly Patients Developing Postoperative Delirium.Front Aging Neurosci2022
35237133Migraine Aura, Transient Ischemic Attacks, Stroke, and Dying of the Brain Share the Same Key Pathophysiological Process in Neurons Driven by Gibbs-Donnan Forces, Namely Spreading Depolarization.Front Cell Neurosci2022
34622418Oxygen-Induced and pH-Induced Direct Current Artifacts on Invasive Platinum/Iridium Electrodes for Electrocorticography.Neurocrit Care2021
30819023Na<sup>+</sup>/K<sup>+</sup>-ATPase α isoform deficiency results in distinct spreading depolarization phenotypes.J Cereb Blood Flow Metab2020
31820363Direct electrophysiological evidence that spreading depolarization-induced spreading depression is the pathophysiological correlate of the migraine aura and a review of the spreading depolarization continuum of acute neuronal mass injury.Geroscience2020
31280632Spreading depolarizations in the rat endothelin-1 model of focal cerebellar ischemia.J Cereb Blood Flow Metab2020
30593517Early focal brain injury after subarachnoid hemorrhage correlates with spreading depolarizations.Neurology2019
31888772Lasting s-ketamine block of spreading depolarizations in subarachnoid hemorrhage: a retrospective cohort study.Crit Care2019
31068779Correlates of Spreading Depolarization, Spreading Depression, and Negative Ultraslow Potential in Epidural Versus Subdural Electrocorticography.Front Neurosci2019
31162113Early blood-brain barrier dysfunction predicts neurological outcome following aneurysmal subarachnoid hemorrhage.EBioMedicine2019
29331091Terminal spreading depolarization and electrical silence in death of human cerebral cortex.Ann Neurol2018
30544340Terminal spreading depolarizations causing electrocortical silencing prior to clinical brain death: case report.J Neurosurg2018
29668855The negative ultraslow potential, electrophysiological correlate of infarction in the human cortex.Brain2018
27025768Oxygen availability and spreading depolarizations provide complementary prognostic information in neuromonitoring of aneurysmal subarachnoid hemorrhage patients.J Cereb Blood Flow Metab2017
28350195Standard-sampling microdialysis and spreading depolarizations in patients with malignant hemispheric stroke.J Cereb Blood Flow Metab2017
28969382Subarachnoid blood acutely induces spreading depolarizations and early cortical infarction.Brain2017
28948141Simulation of spreading depolarization trajectories in cerebral cortex: Correlation of velocity and susceptibility in patients with aneurysmal subarachnoid hemorrhage.Neuroimage Clin2017
27328690The continuum of spreading depolarizations in acute cortical lesion development: Examining Leão's legacy.J Cereb Blood Flow Metab2017
27113903The Hijdra scale has significant prognostic value for the functional outcome of Fisher grade 3 patients with subarachnoid hemorrhage.Clin Neuroradiol2017
27317657Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group.J Cereb Blood Flow Metab2017
26994042A role of the sodium pump in spreading ischemia in rats.J Cereb Blood Flow Metab2017
27258449Complications in Aneurysmal Subarachnoid Hemorrhage Patients With and Without Subdural Electrode Strip for Electrocorticography.J Clin Neurophysiol2016
27906976A Laboratory Critical Incident and Error Reporting System for Experimental Biomedicine.PLoS Biol2016
22890658Spreading ischemia after aneurysmal subarachnoid hemorrhage.Acta Neurochir Suppl2013
23446683Propagation of cortical spreading depolarization in the human cortex after malignant stroke.Neurology2013
23291193Blood-brain barrier opening to large molecules does not imply blood-brain barrier opening to small ions.Neurobiol Dis2013
23287786Electrochemical failure of the brain cortex is more deleterious when it is accompanied by low perfusion.Stroke2013
22890662Criteria for the diagnosis of noninfectious and infectious complications after aneurysmal subarachnoid hemorrhage in DISCHARGE-1.Acta Neurochir Suppl2013
22146193Delayed cerebral ischemia and spreading depolarization in absence of angiographic vasospasm after subarachnoid hemorrhage.J Cereb Blood Flow Metab2012
23134492Impaired neurovascular coupling to ictal epileptic activity and spreading depolarization in a patient with subarachnoid hemorrhage: possible link to blood-brain barrier dysfunction.Epilepsia2012
22366798Correlates of spreading depolarization in human scalp electroencephalography.Brain2012
22120143Spreading convulsions, spreading depolarization and epileptogenesis in human cerebral cortex.Brain2012
21116925Endothelin-1(1-31) induces spreading depolarization in rats.Acta Neurochir Suppl2011
21541244A novel algorithm for the assessment of blood-brain barrier permeability suggests that brain topical application of endothelin-1 does not cause early opening of the barrier in rats.Cardiovasc Psychiatry Neurol2011
20332797Experimental and preliminary clinical evidence of an ischemic zone with prolonged negative DC shifts surrounded by a normally perfused tissue belt with persistent electrocorticographic depression.J Cereb Blood Flow Metab2010
19494192Recovery of slow potentials in AC-coupled electrocorticography: application to spreading depolarizations in rat and human cerebral cortex.J Neurophysiol2009
19420089Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid haemorrhage.Brain2009
17188501Blood-brain barrier disruption results in delayed functional and structural alterations in the rat neocortex.Neurobiol Dis2007
17259327Endothelin-1-induced spreading depression in rats is associated with a microarea of selective neuronal necrosis.Exp Biol Med (Maywood)2007
16773555[Questionnaire study on the acceptance of a student initiative for computer-based medical education].Gesundheitswesen2006
17067993Delayed ischaemic neurological deficits after subarachnoid haemorrhage are associated with clusters of spreading depolarizations.Brain2006
15879337Increased extracellular K+ concentration reduces the efficacy of N-methyl-D-aspartate receptor antagonists to block spreading depression-like depolarizations and spreading ischemia.Stroke2005
14656702ET-1 induces cortical spreading depression via activation of the ETA receptor/phospholipase C pathway in vivo.Am J Physiol Heart Circ Physiol2004
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Collaborators

Center for Stroke Research Berlin, Charite University
Co-authored papers 48
Evangelisches Krankenhaus, Carl von Ossietzky University Oldenburg
Co-authored papers 31
University of Cincinnati
Co-authored papers 22
Robert Koch Institute
Co-authored papers 17
Center for Stroke Research Berlin, Charite-Universitatsmedizin Berlin
Co-authored papers 13
Charite - Universitatsmedizin Berlin
Co-authored papers 12
Charite School of Medicine and University Hospital Berlin
Co-authored papers 11
Charite - Universitatsmedizin Berlin
Co-authored papers 11
Eberhard Karls University of Tuebingen
Co-authored papers 11
Interuniversity Microelectronics Centre
Co-authored papers 10
Center for Stroke Research Berlin
Co-authored papers 10
1 Center for Stroke Research Berlin, Charite University Medicine Berlin
Co-authored papers 9
Dalhousie University
Co-authored papers 9
Heidelberg University Hospital, Ruprecht Karls University of Heidelberg
Co-authored papers 8
University Hospital Cologne
Co-authored papers 8
Center for Stroke Research Berlin, Charite - Universitatsmedizin Berlin
Co-authored papers 7
Charite-Universitatsmedizin
Co-authored papers 7
Heidelberg University Hospital, Ruprecht Karls University of Heidelberg
Co-authored papers 7
Otto-von-Guericke-University
Co-authored papers 7
Copenhagen University Hospital - Rigshospitalet
Co-authored papers 7
University of Pennsylvania, University of Szeged
Co-authored papers 6
The Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev
Co-authored papers 6
Max-Planck-Institute for Neurological Research
Co-authored papers 6
Department of Basic and Clinical Neuroscience, King's College London
Co-authored papers 6
Charite-Universitatsmedizin Berlin
Co-authored papers 6
Rigshospitalet, University of Copenhagen
Co-authored papers 5
Carl-Ludwig-Institute of Physiology, Leipzig University
Co-authored papers 5
University Hospital Bonn
Co-authored papers 4
University Hospital Frankfurt, Goethe-University
Co-authored papers 4
University of Cologne
Co-authored papers 4