Author details

Full Name

Richard N Kitsis

Affiliation

ORCID

Career Start Year

1979

Papers

134

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37100955	Apoptotic cell death in disease-Current understanding of the NCCD 2023.	Cell Death Differ	2023
37924812	Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis.		2023
38091291	The mitochondrial ATP synthase is a negative regulator of the mitochondrial permeability transition pore.		2023
37709008	BAK contributes critically to necrosis and infarct generation during reperfused myocardial infarction.		2023
37696137	Loss of cyclophilin D prolyl isomerase activity desensitizes mitochondrial permeability transition pore opening in isolated cardiac mitochondria, but does not protect in myocardial ischemia-reperfusion injury.		2023
37453667	Introduction to review series: Regulated necrosis programs in heart disease.		2023
35719268	Inducing and measuring apoptotic cell death in mouse pancreatic Î²-cells and in isolated islets.	STAR Protocols	2022
35798717	Modulating mitofusins to control mitochondrial function and signaling.	Nature Communications	2022
35862119	Cardiac Myosin Heavy Chain Reporter Mice to Study Heart Development and Disease.	Circ Res	2022
35544578	IDH2-mediated regulation of the biogenesis of the oxidative phosphorylation system.	Science advances	2022
34382577	Loss of apoptosis repressor with caspase recruitment domain (ARC) worsens high fat diet-induced hyperglycemia in mice.	Journal of Endocrinology	2021
33645548	Immune checkpoint inhibitor-associated myocarditis: manifestations and mechanisms.	Journal of Clinical Investigation	2021
33545060	Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions.	Molecular Cell	2021
34292784	Multiple Cell Death Programs Contribute to Myocardial Infarction.	Circulation Research	2021
33585590	Editorial: Mitochondrial Dysfunction and Cardiovascular Diseases.	Frontiers in Cardiovascular Medicine	2021
33667344	Conversion of the death inhibitor ARC to a killer activates pancreatic Î² cell death in diabetes.	Developmental Cell	2021
33652022	Txnip C247S mutation protects the heart against acute myocardial infarction.	Journal of Molecular and Cellular Cardiology	2021
33597260	Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy.	Sci Transl Med	2021
33336885	Up-regulation of cofilin-1 in cell senescence associates with morphological change and p27 -mediated growth delay.	Aging Cell	2021
32848017	ATG16L1 autophagy pathway regulates BAX protein levels and programmed cell death.	Journal of Biological Chemistry	2020
33094495	Common mechanistic pathways in cancer and heart failure. A scientific roadmap on behalf of the Translational Research Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC).	Eur J Heart Fail	2020
30718816	Small-molecule allosteric inhibitors of BAX.	Nature Chemical Biology	2019
30980035	A mouse model for the most common form of heart failure.	Nature	2019
31364924	Fundamental Mechanisms of Regulated Cell Death and Implications for Heart Disease.	Physiological Reviews	2019
29362479	Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.	Cell Death Differ	2018
29038347	An Akt3 Splice Variant Lacking the Serine 472 Phosphorylation Site Promotes Apoptosis and Suppresses Mammary Tumorigenesis.	Cancer Res	2018
30359137	Heart Disease and Cancer: Are the Two Killers Colluding?	Circulation	2018
30102258	SNAP23 regulates BAX-dependent adipocyte programmed cell death independently of canonical macroautophagy.	Journal of Clinical Investigation	2018
29674596	MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A.	Science	2018
29666279	PDCD5 says no to NO.	Proceedings of the National Academy of Sciences of the United States of America	2018
29700078	RCAN1-Calcineurin Axis and the Set-Point for Myocardial Damage During Ischemia-Reperfusion.	Circulation Research	2018
29593014	Ryanodine Receptor Calcium Leak in Circulating B-Lymphocytes as a Biomarker in Heart Failure.	Circulation	2018
28134239	A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance.	Nat Commun	2017
28774384	Overcoming the Roadblocks to Cardiac Cell Therapy Using Tissue Engineering.	J Am Coll Cardiol	2017
28729244	Apoptosis Repressor With Caspase Recruitment Domain Ameliorates Amyloid-Induced Î²-Cell Apoptosis and JNK Pathway Activation.		2017
28765602	ARC is essential for maintaining pancreatic islet structure and Î²-cell viability during type 2 diabetes.	Scientific Reports	2017
28674089	Grounding Cardio-Oncology in Basic and Clinical Science.	Circulation	2017
28408450	Beyond Mitophagy: The Diversity and Complexity of Parkin Function.	Circulation Research	2017
28924218	Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1.	Nat Commun	2017
29034357	Troponin release following brief myocardial ischemia: apoptosis versus necrosis.	JACC: Basic to Translational Science	2017
28827219	Death Receptor Signaling in the Heart: Cell Survival, Apoptosis, and Necroptosis.	Circulation	2017
28076763	Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise.		2017
28254796	A New Role for the ER Unfolded Protein Response Mediator ATF6: Induction of a Generalized Antioxidant Program.	Circulation Research	2017
28232469	A myeloid tumor suppressor role for .	Journal of Experimental Medicine	2017
27775718	Correcting mitochondrial fusion by manipulating mitofusin conformations.	Nature	2016
27304508	Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise.		2016
26868976	Evaluating mitochondrial autophagy in the mouse heart.	Journal of Molecular and Cellular Cardiology	2016
27126807	Mitochondrial Function, Biology, and Role in Disease: A Scientific Statement From the American Heart Association.	Circ Res	2016
26586571	Catch me if you can: targeting the mitochondrial permeability transition pore in myocardial infarction.	Cell Death and Differentiation	2016
27688304	Does Autophagy Mediate Cardiac Myocyte Death During Stress?	Circulation Research	2016