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Author Details

Erin K O'Shea
Howard Hughes Medical Institute
1989
110
62
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36264273Correction: Evolution of reduced co-activator dependence led to target expansion of a starvation response pathway.Elife2022
34590578The LRRK2 G2019S mutation alters astrocyte-to-neuron communication via extracellular vesicles and induces neuron atrophy in a human iPSC-derived model of Parkinson's disease.Elife2021
30753179A proposal for the future of scientific publishing in the life sciences.PLoS Biol2019
31699926Increasing gender diversity in the STEM research workforce.Science2019
30730292Looking back and looking forward at Janelia.Elife2019
29745899Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates.Elife2018
30029003Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells.Mol Cell2018
30540929An RpaA-Dependent Sigma Factor Cascade Sets the Timing of Circadian Transcriptional Rhythms in Synechococcus elongatus.Cell Rep2018
29357135Dynamical localization of a thylakoid membrane binding protein is required for acquisition of photosynthetic competency.Mol Microbiol2018
28544882Inference and Evolutionary Analysis of Genome-Scale Regulatory Networks in Large Phylogenies.Cell Syst2017
28485712Evolution of reduced co-activator dependence led to target expansion of a starvation response pathway.Elife2017
28430105Switching of metabolic programs in response to light availability is an essential function of the cyanobacterial circadian output pathway.Elife2017
28423314Cyanobacteria Maintain Constant Protein Concentration despite Genome Copy-Number Variation.Cell Rep2017
29241543ppGpp Controls Global Gene Expression in Light and in Darkness in S. elongatus.Cell Rep2017
29239721Natural changes in light interact with circadian regulation at promoters to control gene expression in cyanobacteria.Elife2017
28912235Not just Salk.Science2017
28803778An Unstable Singularity Underlies Stochastic Phasing of the Circadian Clock in Individual Cyanobacterial Cells.Mol Cell2017
28520786A systematic genetic screen for genes involved in sensing inorganic phosphate availability in Saccharomyces cerevisiae.PLoS One2017
27046808Encoding four gene expression programs in the activation dynamics of a single transcription factor.Curr Biol2016
27623011A computational approach to map nucleosome positions and alternative chromatin states with base pair resolution.Elife2016
27403889The anticancer natural product ophiobolin A induces cytotoxicity by covalent modification of phosphatidylethanolamine.Elife2016
25985085Limits on information transduction through amplitude and frequency regulation of transcription factor activity.Elife2015
26279577cis Determinants of Promoter Threshold and Activation Timescale.Cell Rep2015
26600005Correction: Mechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance.Elife2015
26158443High-throughput microfluidics to control and measure signaling dynamics in single yeast cells.Nat Protoc2015
24916159Mechanisms of organelle biogenesis govern stochastic fluctuations in organelle abundance.Elife2014
25416955An integrated approach reveals regulatory controls on bacterial translation elongation.Cell2014
25119046Promoter sequences direct cytoplasmic localization and translation of mRNAs during starvation in yeast.Nature2014
23349292Tunable signal processing through modular control of transcription factor translocation.Science2013
24315105Circadian control of global gene expression by the cyanobacterial master regulator RpaA.Cell2013
24347549A serine sensor for multicellularity in a bacterium.Elife2013
24189399Promoter decoding of transcription factor dynamics involves a trade-off between noise and control of gene expression.Mol Syst Biol2013
23661759Robust circadian oscillations in growing cyanobacteria require transcriptional feedback.Science2013
23541768Two antagonistic clock-regulated histidine kinases time the activation of circadian gene expression.Mol Cell2013
23204469Sequence determinants of circadian gene expression phase in cyanobacteria.J Bacteriol2013
22282809A long-lived lunar core dynamo.Science2012
23231582Genome-wide characterization of the phosphate starvation response in Schizosaccharomyces pombe.BMC Genomics2012
22973550Hog1 controls global reallocation of RNA Pol II upon osmotic shock in Saccharomyces cerevisiae.G3 (Bethesda)2012
22857257The innate immune protein Nod2 binds directly to MDP, a bacterial cell wall fragment.J Am Chem Soc2012
22869746Spatial ordering of chromosomes enhances the fidelity of chromosome partitioning in cyanobacteria.Proc Natl Acad Sci U S A2012
21233390Light-driven changes in energy metabolism directly entrain the cyanobacterial circadian oscillator.Science2011
22179789Signal-dependent dynamics of transcription factor translocation controls gene expression.Nat Struct Mol Biol2011
21612627A high resolution map of a cyanobacterial transcriptome.Genome Biol2011
21700227Integrated approaches reveal determinants of genome-wide binding and function of the transcription factor Pho4.Mol Cell2011
20822907Synthesis of biologically active biotinylated muramyl dipeptides.Bioorg Med Chem Lett2010
19628860Transcriptional regulatory circuits: predicting numbers from alphabets.Science2009
19913541The molecular clockwork of a protein-based circadian oscillator.FEBS Lett2009
20018699Oscillations in supercoiling drive circadian gene expression in cyanobacteria.Proc Natl Acad Sci U S A2009
18059263Molecular basis of cyclin-CDK-CKI regulation by reversible binding of an inositol pyrophosphate.Nat Chem Biol2008
18849996A quantitative model of transcription factor-activated gene expression.Nat Struct Mol Biol2008
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Collaborators

Whitehead Institute for Biomedical Research
Co-authored papers 6
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Broad Institute of MIT and Harvard
Co-authored papers 4
Seoul National University
Co-authored papers 3
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University of California berkeley
Co-authored papers 2
University of Rochester
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
Co-authored papers 1
VIB-VUB Center for Structural Biology
Co-authored papers 1
Yale University
Co-authored papers 1
Tel Aviv University
Co-authored papers 1
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University of California San Francisco
Co-authored papers 1
University of California davis
Co-authored papers 1
Co-authored papers 1
Broad Institute of MIT and Harvard
Co-authored papers 1
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
University Hospital of Wales
Co-authored papers 1
University of Regina
Co-authored papers 1
Weill Institute for Cell and Molecular Biology, Cornell University
Co-authored papers 1
Co-authored papers 1
Carnegie Institution for Science/Howard Hughes Medical Institute
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Sanofi Pasteur Ltd.
Co-authored papers 1