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Author Details

Harmit S Malik
Fred Hutchinson Cancer Center
1997
153
58
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36763410Expansion and loss of sperm nuclear basic protein genes in <i>Drosophila</i> correspond with genetic conflicts between sex chromosomes.Elife2023
37866057Editorial overview: Conflicts, conflicts everywhere.Curr Opin Genet Dev2023
37796130A single polymorphic residue in humans underlies species-specific restriction of HSV-1 by the antiviral protein MxB.J Virol2023
37745568The diverse evolutionary histories of domesticated metaviral capsid genes in mammals.bioRxiv2023
37986796Evolutionary origin and structural ligand mimicry by the inserted domain of alpha-integrin proteins.bioRxiv2023
37398298A single polymorphic residue in humans underlies species-specific restriction of HSV-1 by the antiviral protein MxB.bioRxiv2023
35080919Evolutionary Landscapes of Host-Virus Arms Races.Annu Rev Immunol2022
35365639A functional map of HIV-host interactions in primary human T cells.Nat Commun2022
36173809Recurrent but Short-Lived Duplications of Centromeric Proteins in Holocentric Caenorhabditis Species.Mol Biol Evol2022
35099534Novel Classes and Evolutionary Turnover of Histone H2B Variants in the Mammalian Germline.Mol Biol Evol2022
33473122Short H2A histone variants are expressed in cancer.Nat Commun2021
33879567A balancing act between primate lentiviruses and their receptor.Proc Natl Acad Sci U S A2021
33886542Putting the brakes on centromere drive in Mimulus.PLoS Genet2021
34644300The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity.PLoS Biol2021
34282725An actin-related protein that is most highly expressed in <i>Drosophila</i> testes is critical for embryonic development.Elife2021
33373584Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases.Mol Cell2021
32125433Ancient Coretention of Paralogs of Cid Centromeric Histones and Cal1 Chaperones in Mosquito Species.Mol Biol Evol2020
31697328A Burst of Genetic Innovation in Drosophila Actin-Related Proteins for Testis-Specific Function.Mol Biol Evol2020
32077945Dynamic Evolution of De Novo DNA Methyltransferases in Rodent and Primate Genomes.Mol Biol Evol2020
33169670Innovation of heterochromatin functions drives rapid evolution of essential ZAD-ZNF genes in <i>Drosophila</i>.Elife2020
33362208Biparental contributions of the H2A.B histone variant control embryonic development in mice.PLoS Biol2020
33063663A natural variant of the essential host gene <i>MMS21</i> restricts the parasitic 2-micron plasmid in <i>Saccharomyces cerevisiae</i>.Elife2020
32930662Mutational resilience of antiviral restriction favors primate TRIM5α in host-virus evolutionary arms races.Elife2020
32353859A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.Nature2020
32479260Retrocopying expands the functional repertoire of APOBEC3 antiviral proteins in primates.Elife2020
31134893Density-dependent resistance protects <i>Legionella pneumophila</i> from its own antimicrobial metabolite, HGA.Elife2019
31841515Hybridization promotes asexual reproduction in Caenorhabditis nematodes.PLoS Genet2019
31794760Meiosis: How Gambling Chromosomes Beat the Rules.Curr Biol2019
31558570EvoChromo: towards a synthesis of chromatin biology and evolution.Development2019
31574080Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins.PLoS Biol2019
30811478The PLOS Biology XV Collection: 15 Years of Exceptional Science Highlighted across 12 Months.PLoS Biol2019
29454259The cellular mechanisms and consequences of centromere drive.Curr Opin Cell Biol2018
29727667Kindr Motors Drive in Meiosis.Cell2018
29549088Evolutionary origins and diversification of testis-specific short histone H2A variants in mammals.Genome Res2018
29689213Microbial Genomics: The Expanding Universe of Bacterial Defense Systems.Curr Biol2018
28057823Genetic conflicts: the usual suspects and beyond.J Exp Biol2017
28333217Recurrent Gene Duplication Leads to Diverse Repertoires of Centromeric Histones in Drosophila Species.Mol Biol Evol2017
29251593Culture shock.Elife2017
28541576Rapidly Evolving Toll-3/4 Genes Encode Male-Specific Toll-Like Receptors in Drosophila.Mol Biol Evol2017
28512238Corrigendum: Evolution of a transcriptional regulator from a transmembrane nucleoporin.Genes Dev2017
28727819The gene drive bubble: New realities.PLoS Genet2017
28874454Waddington Redux: <i>De Novo</i> Mutations Underlie the Genetic Assimilation of Stress-Induced Phenocopies in <i>Drosophila melanogaster</i>.Genetics2017
28898647Genetics: Master Regulator or Master of Disguise?Curr Biol2017
28631612<i>wtf</i> genes are prolific dual poison-antidote meiotic drivers.Elife2017
26821364Hide and seek: how chromatin-based pathways silence retroelements in the mammalian germline.Curr Opin Genet Dev2016
28087716The piggyBac transposon-derived genes TPB1 and TPB6 mediate essential transposon-like excision during the developmental rearrangement of key genes in Tetrahymena thermophila.Genes Dev2016
29092666A Diversified Portfolio.Annu Rev Virol2016
27814518Did a Single Amino Acid Change Make Ebola Virus More Virulent?Cell2016
27240734Evolution-guided functional analyses reveal diverse antiviral specificities encoded by IFIT1 genes in mammals.Elife2016
27481326A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility in Drosophila melanogaster.Elife2016
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Collaborators

Michael Emerman
Fred Hutchinson Cancer Center
Co-authored papers 28
Janet M Young
Fred Hutchinson Cancer Research Center
Co-authored papers 20
Steven Henikoff
Fred Hutchinson Cancer Center
Co-authored papers 17
Nels C Elde
University of Utah School of Medicine
Co-authored papers 4
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 2
Mehdi Bouhaddou
J. David Gladstone Institutes
Co-authored papers 2
Joseph B Hiatt
Fred Hutchinson Cancer Center
Co-authored papers 2
Michael J McGregor
J. David Gladstone Institutes
Co-authored papers 2
Juan Ausi??
University of Victoria
Co-authored papers 2
Theodore L Roth
Stanford University
Co-authored papers 2
Jay Shendure
University of Washington
Co-authored papers 2
Ujjwal Rathore
University of California san francisco
Co-authored papers 2
Christopher Benner
Michigan State University College of Human Medicine
Co-authored papers 2
Kelsey M Haas
J. David Gladstone Institutes
Co-authored papers 2
R Keith Slotkin
Co-authored papers 2
Georg Kochs
Institute of Virology, Freiburg University Medical Center, University of Freiburg
Co-authored papers 2
George M Church
Harvard Medical School
Co-authored papers 1
Omar S Akbari
University of California
Co-authored papers 1
Alan D Frankel
University of California san francisco
Co-authored papers 1
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Paige Haas
Gladstone Institutes
Co-authored papers 1
Eric Shifrut
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 1
Maria-Elena Torres-Padilla
Institute of Epigenetics and Stem Cells (IES)
Co-authored papers 1
Eric Verdin
Buck Institute for Research on Aging
Co-authored papers 1
Danica Galoni?? Fujimori
University of California San Francisco
Co-authored papers 1
Kevin L Gunderson
Illumina Inc.
Co-authored papers 1
Davide Ruggero
University of California San Francisco
Co-authored papers 1
Ying Shi
Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences
Co-authored papers 1
Phillip P Sharp
University of California san francisco
Co-authored papers 1
David A Agard
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 1
Release 1.2