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Author Details

Patrick C A van der Wel
Zernike Institute for Advanced Materials, University of Groningen
1999
65
32
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36750751New insights in polydopamine formation via surface adsorption.Nat Commun2023
37996701Anomalous peroxidase activity of cytochrome c is the primary pathogenic target in Barth syndrome.Nat Metab2023
37502911Integrative determination of the atomic structure of mutant huntingtin exon 1 fibrils from Huntington's disease.bioRxiv2023
37321744Production of isotopically enriched high molecular weight hyaluronic acid and characterization by solid-state NMR.Carbohydr Polym2023
36592488Fast magic angle spinning for the characterization of milligram quantities of organic and biological solids at natural isotopic abundance by <sup>13</sup>C-<sup>13</sup>C correlation DNP-enhanced NMR.Solid State Nucl Magn Reson2023
36419510Selective observation of semi-rigid non-core residues in dynamically complex mutant huntingtin protein fibrils.J Struct Biol X2022
35485142Structural Dynamics and Tunability for Colloidal Tin Halide Perovskite Nanostructures.Adv Mater2022
34261790NMR identification of a conserved Drp1 cardiolipin-binding motif essential for stress-induced mitochondrial fission.Proc Natl Acad Sci U S A2021
33574241Regulatory inter-domain interactions influence Hsp70 recruitment to the DnaJB8 chaperone.Nat Commun2021
34938776Dihedral Angle Measurements for Structure Determination by Biomolecular Solid-State NMR Spectroscopy.Front Mol Biosci2021
34033821Activation of Cytochrome C Peroxidase Function Through Coordinated Foldon Loop Dynamics upon Interaction with Anionic Lipids.J Mol Biol2021
32475563Use of solid-state NMR spectroscopy for investigating polysaccharide-based hydrogels: A review.Carbohydr Polym2020
32598938Protofilament Structure and Supramolecular Polymorphism of Aggregated Mutant Huntingtin Exon 1.J Mol Biol2020
30879887Surface-Binding to Cardiolipin Nanodomains Triggers Cytochrome c Pro-apoptotic Peroxidase Activity via Localized Dynamics.Structure2019
31203656Conformational studies of pathogenic expanded polyglutamine protein deposits from Huntington's disease.Exp Biol Med (Maywood)2019
29254334Energetics Underlying Twist Polymorphisms in Amyloid Fibrils.J Phys Chem B2018
29911185New applications of solid-state NMR in structural biology.Emerg Top Life Sci2018
30339373Structural Fingerprinting of Protein Aggregates by Dynamic Nuclear Polarization-Enhanced Solid-State NMR at Natural Isotopic Abundance.J Am Chem Soc2018
29702226Hidden motions and motion-induced invisibility: Dynamics-based spectral editing in solid-state NMR.Methods2018
29401604Methionine oxidized apolipoprotein A-I at the crossroads of HDL biogenesis and amyloid formation.FASEB J2018
27986569Backbone Engineering within a Latent β-Hairpin Structure to Design Inhibitors of Polyglutamine Amyloid Formation.J Mol Biol2017
28229262On the use of ultracentrifugal devices for routine sample preparation in biomolecular magic-angle-spinning NMR.J Biomol NMR2017
28474685Cataract-associated P23T γD-crystallin retains a native-like fold in amorphous-looking aggregates formed at physiological pH.Nat Commun2017
29035839Insights into protein misfolding and aggregation enabled by solid-state NMR spectroscopy.Solid State Nucl Magn Reson2017
28537272Fibril polymorphism affects immobilized non-amyloid flanking domains of huntingtin exon1 rather than its polyglutamine core.Nat Commun2017
26831073Huntingtin exon 1 fibrils feature an interdigitated β-hairpin-based polyglutamine core.Proc Natl Acad Sci U S A2016
27726354Peptide-Directed Assembly of Single-Helical Gold Nanoparticle Superstructures Exhibiting Intense Chiroptical Activity.J Am Chem Soc2016
27806278MAS <sup>1</sup>H NMR Probes Freezing Point Depression of Water and Liquid-Gel Phase Transitions in Liposomes.Biophys J2016
26536264Structural Changes and Proapoptotic Peroxidase Activity of Cardiolipin-Bound Mitochondrial Cytochrome c.Biophys J2015
24291210D-polyglutamine amyloid recruits L-polyglutamine monomers and kills cells.J Mol Biol2014
25280367Polyglutamine amyloid core boundaries and flanking domain dynamics in huntingtin fragment fibrils determined by solid-state nuclear magnetic resonance.Biochemistry2014
24607141How amyloid precursor protein protects itself from cleavage.Structure2014
23353826β-hairpin-mediated nucleation of polyglutamine amyloid formation.J Mol Biol2013
23475055Spinning-rate encoded chemical shift correlations from rotational resonance solid-state NMR experiments.J Magn Reson2013
22142403Structural characterization of the caveolin scaffolding domain in association with cholesterol-rich membranes.Biochemistry2012
22999956Serine phosphorylation suppresses huntingtin amyloid accumulation by altering protein aggregation properties.J Mol Biol2012
22955930In support of the BMRB.Nat Struct Mol Biol2012
22437737Domain swapping and amyloid fibril conformation.Prion2012
22435461Lipid dynamics and protein-lipid interactions in 2D crystals formed with the β-barrel integral membrane protein VDAC1.J Am Chem Soc2012
21381744The aggregation-enhancing huntingtin N-terminus is helical in amyloid fibrils.J Am Chem Soc2011
21766841Structural complexity of a composite amyloid fibril.J Am Chem Soc2011
21715337Amyloid-like fibrils from a domain-swapping protein feature a parallel, in-register conformation without native-like interactions.J Biol Chem2011
20387894Time averaging of NMR chemical shifts in the MLF peptide in the solid state.J Am Chem Soc2010
20695483Structural characterization of GNNQQNY amyloid fibrils by magic angle spinning NMR.Biochemistry2010
20454733Dynamic nuclear polarization-enhanced solid-state NMR spectroscopy of GNNQQNY nanocrystals and amyloid fibrils.Phys Chem Chem Phys2010
19067520Observation of a low-temperature, dynamically driven structural transition in a polypeptide by solid-state NMR spectroscopy.J Am Chem Soc2009
19596601High-resolution solid-state NMR structure of alanyl-prolyl-glycine.J Magn Reson2009
19356957Cryogenic sample exchange NMR probe for magic angle spinning dynamic nuclear polarization.J Magn Reson2009
19565580Targeted 13C-13C distance measurements in a microcrystalline protein via J-decoupled rotational resonance width measurements.Chemphyschem2009
17827234Helical distortion in tryptophan- and lysine-anchored membrane-spanning alpha-helices as a function of hydrophobic mismatch: a solid-state deuterium NMR investigation using the geometric analysis of labeled alanines method.Biophys J2008
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Collaborators

Valerian E Kagan
Center for Free Radical and Antioxidant Health, University of Pittsburgh
Co-authored papers 4
Michele Vendruscolo
University of Cambridge
Co-authored papers 2
Angela M Gronenborn
University of Pittsburgh
Co-authored papers 2
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Michael R Gryk
University of Illinois
Co-authored papers 1
Walter J Chazin
and Center for Structural Biology, Vanderbilt University
Co-authored papers 1
Bernd Reif
Technische Universitat Munchen (TUM)
Co-authored papers 1
Matthew P Crump
University of Bristol
Co-authored papers 1
Alexander P Golovanov
The University of Manchester
Co-authored papers 1
David A Case
Rutgers University
Co-authored papers 1
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Center for Integrated Protein Science, Technische Universitat Munchen
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Leicester Institute of Structural and Chemical Biology, University of Leicester
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University of Texas Southwestern Medical Center
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The University of Sheffield
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Institute of Integrative Biology, University of Liverpool
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Columbia University
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National Institutes of Health
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David Middleton
Co-authored papers 1
Ioannis Vakonakis
University of Oxford
Co-authored papers 1
Thomas A Frenkiel
The Medical Research Council Biomedical NMR Centre, The Francis Crick Institute
Co-authored papers 1
Ernest D Laue
University of Cambridge
Co-authored papers 1
Gordon S Rule
Carnegie Mellon University
Co-authored papers 1
Stephen Matthews
Imperial College London
Co-authored papers 1
Chien Ho
Carnegie Mellon University
Co-authored papers 1
Toshimichi Fujiwara
Institute for Protein Research, Osaka University
Co-authored papers 1
Pei Tang
Sichuan University
Co-authored papers 1
Joern Werner
Co-authored papers 1
Paul C Driscoll
The Francis Crick Institute
Co-authored papers 1
Shigeyuki Yokoyama
Shinshu University School of Medicine
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Release 1.2