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Author Details

Hugh D Mitchell
Pacific Northwest National Laboratory (PNNL)
2002
47
23
PMIDPaper TitleJournal TitlePublished Year
37162945A crucial role for dynamic expression of components encoding the negative arm of the circadian clock.bioRxiv2023
37291101A crucial role for dynamic expression of components encoding the negative arm of the circadian clock.Nat Commun2023
37265358Modulation of Polar Auxin Transport Identifies the Molecular Determinants of Source-Sink Carbon Relationships and Sink Strength in Poplar.Tree Physiol2023
34845335Novel metabolic interactions and environmental conditions mediate the boreal peatmoss-cyanobacteria mutualism.ISME J2022
35348388Capturing an Early Gene Induction Event during Wood Decay by the Brown Rot Fungus <i>Rhodonia placenta</i>.Appl Environ Microbiol2022
35793793Uncovering Hidden Members and Functions of the Soil Microbiome Using <i>De Novo</i> Metaproteomics.J Proteome Res2022
35290009Expression Patterns of Energy-Related Genes in Single Cells Uncover Key Isoforms and Enzymes That Gain Priority Under Nanoparticle-Induced Stress.ACS Nano2022
35150839Distinctive carbon repression effects in the carbohydrate-selective wood decay fungus Rhodonia placenta.Fungal Genet Biol2022
33402348Metabolic Interactions between <i>Brachypodium</i> and Pseudomonas fluorescens under Controlled Iron-Limited Conditions.mSystems2021
33763411Re-routing of Sugar Catabolism Provides a Better Insight Into Fungal Flexibility in Using Plant Biomass-Derived Monomers as Substrates.Front Bioeng Biotechnol2021
33622792Intracellular pathways for lignin catabolism in white-rot fungi.Proc Natl Acad Sci U S A2021
33638890Night shift schedule causes circadian dysregulation of DNA repair genes and elevated DNA damage in humans.J Pineal Res2021
33703901leapR: An R Package for Multiomic Pathway Analysis.J Proteome Res2021
34051754Hypergraph models of biological networks to identify genes critical to pathogenic viral response.BMC Bioinformatics2021
34372702Unfolded Protein Response Inhibition Reduces Middle East Respiratory Syndrome Coronavirus-Induced Acute Lung Injury.mBio2021
31911630Automated mass spectrometry imaging of over 2000 proteins from tissue sections at 100-μm spatial resolution.Nat Commun2020
31876091Colonies of the fungus Aspergillus niger are highly differentiated to adapt to local carbon source variation.Environ Microbiol2020
31928885Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention.Cell Metab2020
30529285Reference genes for accurate normalization of gene expression in wood-decomposing fungi.Fungal Genet Biol2019
31616667The Role of EGFR in Influenza Pathogenicity: Multiple Network-Based Approaches to Identify a Key Regulator of Non-lethal Infections.Front Cell Dev Biol2019
30979841Wetland Sediments Host Diverse Microbial Taxa Capable of Cycling Alcohols.Appl Environ Microbiol2019
29339515MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscape.Proc Natl Acad Sci U S A2018
29976657Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines.J Virol2018
29516783Time-resolved proteome profiling of normal lung development.Am J Physiol Lung Cell Mol Physiol2018
28830941MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis.mBio2017
29152578Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis.mSphere2017
29049419Multi-time series RNA-seq analysis of Enterobacter lignolyticus SCF1 during growth in lignin-amended medium.PLoS One2017
27663205The effect of inhibition of PP1 and TNFα signaling on pathogenesis of SARS coronavirus.BMC Syst Biol2016
27788331Cells Respond to Distinct Nanoparticle Properties with Multiple Strategies As Revealed by Single-Cell RNA-Seq.ACS Nano2016
25388675CpG preconditioning regulates miRNA expression that modulates genomic reprogramming associated with neuroprotection against ischemic injury.J Cereb Blood Flow Metab2015
24659771The highly conserved MraZ protein is a transcriptional regulator in Escherichia coli.J Bacteriol2014
25977790A comprehensive collection of systems biology data characterizing the host response to viral infection.Sci Data2014
25547186Transcriptomic and proteomic dynamics in the metabolism of a diazotrophic cyanobacterium, Cyanothece sp. PCC 7822 during a diurnal light-dark cycle.BMC Genomics2014
23147219A multi-omic systems approach to elucidating Yersinia virulence mechanisms.Mol Biosyst2013
23935999A network integration approach to predict conserved regulators related to pathogenicity of influenza and SARS-CoV respiratory viruses.PLoS One2013
23559334Salmonella modulates metabolism during growth under conditions that induce expression of virulence genes.Mol Biosyst2013
23335946Challenges in Biomarker Discovery: Combining Expert Insights with Statistical Analysis of Complex Omics Data.Expert Opin Med Diagn2013
22745654Identification and validation of Ifit1 as an important innate immune bottleneck.PLoS One2012
21224363Combination therapy with vidaza and entinostat suppresses tumor growth and reprograms the epigenome in an orthotopic lung cancer model.Cancer Res2011
21068247Higher level of replication efficiency of 2009 (H1N1) pandemic influenza virus than those of seasonal and avian strains: kinetics from epithelial cell culture and computational modeling.J Virol2011
19006074A novel fluorescent cross-reactive formylpeptide receptor/formylpeptide receptor-like 1 hexapeptide ligand.Cytometry A2009
17655271Synthetic estrogen derivatives demonstrate the functionality of intracellular GPR30.ACS Chem Biol2007
16288034Transforming growth factor-beta activation of phosphatidylinositol 3-kinase is independent of Smad2 and Smad3 and regulates fibroblast responses via p21-activated kinase-2.Cancer Res2005
15075369Differential trafficking of transforming growth factor-beta receptors and ligand in polarized epithelial cells.Mol Biol Cell2004
15229286Ligand-dependent and -independent transforming growth factor-beta receptor recycling regulated by clathrin-mediated endocytosis and Rab11.Mol Biol Cell2004
15050948A new approach to managing prostate cancer is essential.Lancet Oncol2004
12052882Internalization-dependent and -independent requirements for transforming growth factor beta receptor signaling via the Smad pathway.Mol Cell Biol2002
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Collaborators

Jason E McDermott
Pacific Northwest National Laboratory
Co-authored papers 14
Katrina M Waters
Pacific Northwest National Laboratory
Co-authored papers 10
Ralph S Baric
University of North Carolina
Co-authored papers 10
Thomas O Metz
Pacific Northwest National Laboratory
Co-authored papers 8
Lisa E Gralinski
University of North Carolina at Chapel Hill
Co-authored papers 8
Richard D Smith
Pacific Northwest National Laboratory
Co-authored papers 7
Amy C Sims
The University of North Carolina at Chapel Hill
Co-authored papers 7
Bobbie-Jo M Webb-Robertson
Pacific Northwest National Laboratory
Co-authored papers 6
Vineet D Menachery
University of Texas Medical Branch
Co-authored papers 6
Amie J Eisfeld
Influenza Research Institute, University of Wisconsin-Madison
Co-authored papers 6
Kelly G Stratton
Pacific Northwest National Laboratory
Co-authored papers 6
Yoshihiro Kawaoka
Influenza Research Institute, University of Wisconsin
Co-authored papers 5
Kristin E Burnum-Johnson
Pacific Northwest National Laboratory
Co-authored papers 4
Young-Mo Kim
Hanyang University
Co-authored papers 4
Boyd L Yount
University of North Carolina at Chapel Hill
Co-authored papers 4
Charles Ansong
Pacific Northwest National Laboratory
Co-authored papers 4
Susan C Tilton
Oregon State University
Co-authored papers 3
Laurence Josset
Institut des Agents Infectieux, Infective Agents Institute, North Hospital Network
Co-authored papers 3
Marina A Gritsenko
Pacific Northwest National Laboratory
Co-authored papers 3
Anil K Shukla
Pacific Northwest National Laboratory
Co-authored papers 3
Chengjun Li
Harbin Veterinary Research Institute
Co-authored papers 3
Shufang Fan
Influenza Research Institute, University of Wisconsin
Co-authored papers 3
Gabriele Neumann
Influenza Research Institute, University of Wisconsin-Madison
Co-authored papers 3
Rachel L Graham
University of North Carolina
Co-authored papers 3
Michael G Katze
University of Washington
Co-authored papers 3
Samuel O Purvine
Pacific Northwest National Laboratory
Co-authored papers 3
Rosalie K Chu
Co-authored papers 3
Lisa M Bramer
Co-authored papers 3
Jennifer J Loros
Geisel School of Medicine at Dartmouth
Co-authored papers 2
Jean Chang
Center for Innate Immunity and Immune Disease, University of Washington
Co-authored papers 2
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