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Author Details

Minghui Wang
Icahn School of Medicine at Mount Sinai
2007
91
36
PMIDPaper TitleJournal TitlePublished Year
36630956Multi-omic integration reveals cell-type-specific regulatory networks of insulin resistance in distinct ancestry populations.Cell Syst2023
37857825Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer's disease.Nat Immunol2023
37662269Dual-specificity protein phosphatase 6 (DUSP6) overexpression reduces amyloid load and improves memory deficits in male 5xFAD mice.bioRxiv2023
37686033The Expression of P35 Plays a Key Role in the Difference in Apoptosis Induced by AcMNPV Infection in Different <i>Spodoptera exigua</i> Cell Lines.Int J Mol Sci2023
37684260Multi-omic atlas of the parahippocampal gyrus in Alzheimer's disease.Sci Data2023
37020385Tuberous sclerosis complex-1 (TSC1) contributes to selective neuronal vulnerability in Alzheimer's disease.Neuropathol Appl Neurobiol2023
37082147Convergent coexpression of autism-associated genes suggests some novel risk genes may not be detectable in large-scale genetic studies.Cell Genom2023
37284017Molecular differences in brain regional vulnerability to aging between males and females.Front Aging Neurosci2023
37147110Multiomics Analyses Identify Proline Endopeptidase-Like Protein As a Key Regulator of Protein Trafficking, a Pathway Underlying Alzheimer's Disease Pathogenesis.Mol Pharmacol2023
37340466Sex specific molecular networks and key drivers of Alzheimer's disease.Mol Neurodegener2023
37435531Dysfunction of ubiquitin protein ligase <i>MYCBP2</i> leads to cell resilience in human breast cancers.NAR Cancer2023
37231161Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence.Nat Cell Biol2023
36448627Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease.Alzheimers Dement2023
36718369Single-cell RNA sequencing reveals the suppressive effect of PPP1R15A inhibitor Sephin1 in antitumor immunity.iScience2023
36811307Genome-wide methylomic regulation of multiscale gene networks in Alzheimer's disease.Alzheimers Dement2023
34130857Chronic Intermittent Hypoxia Enhances Pathological Tau Seeding, Propagation, and Accumulation and Exacerbates Alzheimer-like Memory and Synaptic Plasticity Deficits and Molecular Signatures.Biol Psychiatry2022
35479404Sex disparities in influenza: A multiscale network analysis.iScience2022
35750033Cholesterol and matrisome pathways dysregulated in astrocytes and microglia.Cell2022
36497141Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces β-Amyloid Load in Males and Females.Cells2022
36419137Opposing effects of apoE2 and apoE4 on microglial activation and lipid metabolism in response to demyelination.Mol Neurodegener2022
36040157Hydrogel-Embedded Poly(Lactic-<i>co</i>-Glycolic Acid) Microspheres for the Delivery of hMSC-Derived Exosomes to Promote Bioactive Annulus Fibrosus Repair.Cartilage2022
36197970Common and species-specific molecular signatures, networks, and regulators of influenza virus infection in mice, ferrets, and humans.Sci Adv2022
36323256Spatiotemporal and genetic regulation of A-to-I editing throughout human brain development.Cell Rep2022
35915180Peripheral apoE4 enhances Alzheimer's pathology and impairs cognition by compromising cerebrovascular function.Nat Neurosci2022
34918867Whole genome sequencing-based copy number variations reveal novel pathways and targets in Alzheimer's disease.Alzheimers Dement2022
35000600The landscape of human tissue and cell type specific expression and co-regulation of senescence genes.Mol Neurodegener2022
35236372Guidelines for bioinformatics of single-cell sequencing data analysis in Alzheimer's disease: review, recommendation, implementation and application.Mol Neurodegener2022
34757660Integrative metabolomics-genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease.Alzheimers Dement2022
33238137Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease.Neuron2021
35531351Profiling senescent cells in human brains reveals neurons with CDKN2D/p19 and tau neuropathology.Nat Aging2021
33619278Network models of primary melanoma microenvironments identify key melanoma regulators underlying prognosis.Nat Commun2021
33523961Molecular subtyping of Alzheimer's disease using RNA sequencing data reveals novel mechanisms and targets.Sci Adv2021
34857756Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue.Nat Commun2021
34851693AD-linked R47H-<i>TREM2</i> mutation induces disease-enhancing microglial states via AKT hyperactivation.Sci Transl Med2021
34924992Transcriptomic Changes Highly Similar to Alzheimer's Disease Are Observed in a Subpopulation of Individuals During Normal Brain Aging.Front Aging Neurosci2021
34561470Author Correction: Brain Cell Type Specific Gene Expression and Co-expression Network Architectures.Sci Rep2021
33314529Reactive or transgenic increase in microglial TYROBP reveals a TREM2-independent TYROBP-APOE link in wild-type and Alzheimer's-related mice.Alzheimers Dement2021
32485136CD49f Is a Novel Marker of Functional and Reactive Human iPSC-Derived Astrocytes.Neuron2020
31937643Cell-to-Cell Variation in Defective Virus Expression and Effects on Host Responses during Influenza Virus Infection.mBio2020
31926610Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression.Neuron2020
32062565Systems modeling of white matter microstructural abnormalities in Alzheimer's disease.Neuroimage Clin2020
32770063Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease.Nat Commun2020
32934258Males and females exhibit distinct relationships between intervertebral disc degeneration and pain in a rat model.Sci Rep2020
32879487The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer's disease.Nature2020
32668255Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models.Cell Rep2020
32284590Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.Nat Med2020
32178738Characterization of antibiotic resistance and host-microbiome interactions in the human upper respiratory tract during influenza infection.Microbiome2020
32437656Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression.Neuron2020
29740122Differential activity of transcribed enhancers in the prefrontal cortex of 537 cases with schizophrenia and controls.Mol Psychiatry2019
31748532The landscape of multiscale transcriptomic networks and key regulators in Parkinson's disease.Nat Commun2019
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Collaborators

Graduate School of Medicine, The University of Tokyo
Co-authored papers 49
Icahn School of Medicine at Mount Sinai
Co-authored papers 24
Co-authored papers 16
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Co-authored papers 16
Icahn School of Medicine at Mount Sinai
Co-authored papers 9
Co-authored papers 9
Rush University Medical Center
Co-authored papers 8
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Co-authored papers 8
Columbia University Medical Center
Co-authored papers 7
Icahn School of Medicine at Mount Sinai.
Co-authored papers 6
Co-authored papers 6
Co-authored papers 6
Emory University School of Medicine
Co-authored papers 6
Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine
Co-authored papers 6
Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine
Co-authored papers 5
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 5
Co-authored papers 5
Co-authored papers 4
Co-authored papers 4
Mayo Clinic
Co-authored papers 4
Icahn School of Medicine at Mount Sinai
Co-authored papers 4
Co-authored papers 3
Institute for Next Generation Healthcare
Co-authored papers 3
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Fred Hutchinson Cancer Research Center
Co-authored papers 3
Mayo Clinic
Co-authored papers 3
Emory Center for Neurodegenerative Disease
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3