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Author Details

Nan-Hua Chang
Krembil Research Institute, University Health Network
1991
24
12
PMIDPaper TitleJournal TitlePublished Year
32722684Impaired B cell anergy is not sufficient to breach tolerance to nuclear antigen in Vκ8/3H9 lupus-prone mice.PLoS One2020
29742110Identification of a neutrophil-related gene expression signature that is enriched in adult systemic lupus erythematosus patients with active nephritis: Clinical/pathologic associations and etiologic mechanisms.PLoS One2018
30486869The presence of anti-nuclear antibodies alone is associated with changes in B cell activation and T follicular helper cells similar to those in systemic autoimmune rheumatic disease.Arthritis Res Ther2018
28628673Multiple tolerance defects contribute to the breach of B cell tolerance in New Zealand Black chromosome 1 congenic mice.PLoS One2017
28373584Invariant NKT Cell Activation Is Potentiated by Homotypic <i>trans</i>-Ly108 Interactions.J Immunol2017
26964093IL-10 Production Is Critical for Sustaining the Expansion of CD5+ B and NKT Cells and Restraining Autoantibody Production in Congenic Lupus-Prone Mice.PLoS One2016
25678471Interferon-α induces altered transitional B cell signaling and function in Systemic Lupus Erythematosus.J Autoimmun2015
25973757Suppression of autoimmunity by CD5(+) IL-10-producing B cells in lupus-prone mice.Genes Immun2015
23328841Identification of a lupus-susceptibility locus leading to impaired clearance of apoptotic debris on New Zealand Black chromosome 13.Genes Immun2013
21268021An intrinsic B-cell defect supports autoimmunity in New Zealand black chromosome 13 congenic mice.Eur J Immunol2011
21414847Abrogation of pathogenic IgG autoantibody production in CD40L gene-deleted lupus-prone New Zealand Black mice.Clin Immunol2011
21464090Epistatic suppression of fatal autoimmunity in New Zealand black bicongenic mice.J Immunol2011
20110518Bone marrow-derived human hematopoietic stem cells engraft NOD/SCID mice and traffic appropriately to an inflammatory stimulus in the joint.J Rheumatol2010
20661465B cell activating factor (BAFF) and T cells cooperate to breach B cell tolerance in lupus-prone New Zealand Black (NZB) mice.PLoS One2010
18178868Expanded population of activated antigen-engaged cells within the naive B cell compartment of patients with systemic lupus erythematosus.J Immunol2008
16301643Aberrant IgM signaling promotes survival of transitional T1 B cells and prevents tolerance induction in lupus-prone New Zealand black mice.J Immunol2005
16339554Functional interplay between intrinsic B and T cell defects leads to amplification of autoimmune disease in New Zealand black chromosome 1 congenic mice.J Immunol2005
14734734Autoreactive B cells in lupus-prone New Zealand black mice exhibit aberrant survival and proliferation in the presence of self-antigen in vivo.J Immunol2004
12902468Functional dissection of lupus susceptibility loci on the New Zealand black mouse chromosome 1: evidence for independent genetic loci affecting T and B cell activation.J Immunol2003
10349907Large ex vivo expansion of human umbilical cord blood CD4+ and CD8+ T cells.J Hematother1999
9073386Selective elimination of antigen-specific line T cells and ex vivo antigen-primed lymph node cells by antigen-targeted drug-labeled antigen-presenting cell membranes.Cell Immunol1997
7539530Targeting of phototoxic drugs to antigen-specific T lymphocytes in vitro using antigen-presenting cell membranes.Photochem Photobiol1995
1377989Stimulation or tolerization of an anti-myelin basic protein T lymphocyte line with membrane fragments from antigen presenting cells.Cell Immunol1992
1854170Liposomal amphotericin B inhibits in vitro T-lymphocyte response to antigen.Antimicrob Agents Chemother1991
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Collaborators

Joan E Wither
Schroeder Arthritis Institute, Krembil Research Institute, University Health Network
Co-authored papers 19
Carolina Landolt-Marticorena
Krembil Research Institute, University Health Network
Co-authored papers 4
Paul R Fortin
Centre de recherche du Centre hospitalier universitaire de Quebec-Universite Laval
Co-authored papers 3
Murray B Urowitz
Schroeder Arthritis Institute, Krembil Research Institute, University Health Network
Co-authored papers 2
Dennisse Bonilla
Toronto Western Hospital and Schroeder Arthritis Institute, University Health Network
Co-authored papers 2
Dafna D Gladman
Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital
Co-authored papers 2
Babak Noamani
Princess Margaret Cancer Center, University Health Network
Co-authored papers 2
Timothy T Li
The University of Western Ontario
Co-authored papers 2
Carmen Avila-Casado
University Health Network
Co-authored papers 1
John E Dick
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 1
Heather N Reich
University Health Network and University of Toronto
Co-authored papers 1
Sindhu R Johnson
Toronto Western Hospital, University of Toronto
Co-authored papers 1
Zahi Touma
Schroeder Arthritis Institute, Krembil Research Institute, University Health Network
Co-authored papers 1
Paul C Boutros
University of California los angeles
Co-authored papers 1
Stephenie D Prokopec
University Health Network
Co-authored papers 1
Arthur Bookman
University of Toronto
Co-authored papers 1
James W Scholey
University Health Network, University of Toronto
Co-authored papers 1
Release 1.2