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Author Details

Wilbert Zwart
Oncode Institute, The Netherlands Cancer Institute
2004
147
40
PMIDPaper TitleJournal TitlePublished Year
37854018Proteomics on malignant pleural effusions reveals ERα loss in metastatic breast cancer associates with SGK1-NDRG1 deregulation.Mol Oncol2024
36669105Mammalian life depends on two distinct pathways of DNA damage tolerance.Proc Natl Acad Sci U S A2023
37961147Breast cancer risk SNPs converge on estrogen receptor binding sites commonly shared between breast tumors to locally alter estrogen signalling output.bioRxiv2023
37554550Exploring the Onset and Progression of Prostate Cancer through a Multicellular Agent-based Model.Cancer Res Commun2023
37902007Luminal breast cancer identity is determined by loss of glucocorticoid receptor activity.EMBO Mol Med2023
37791849Compartmentalization of androgen receptors at endogenous genes in living cells.Nucleic Acids Res2023
37694973Transposable Elements Are Co-opted as Oncogenic Regulatory Elements by Lineage-Specific Transcription Factors in Prostate Cancer.Cancer Discov2023
37578563Crosstalk between glucocorticoid and mineralocorticoid receptors boosts glucocorticoid-induced killing of multiple myeloma cells.Cell Mol Life Sci2023
37733591Perturbations in 3D genome organization can promote acquired drug resistance.Cell Rep2023
37535891Inhibiting the Glucocorticoid Receptor to Enhance Chemotherapy Response.J Clin Oncol2023
37770115TRIM25 targets p300 for degradation.Life Sci Alliance2023
37370685Radiogenomics Analysis Linking Multiparametric MRI and Transcriptomics in Prostate Cancer.Cancers (Basel)2023
37271632Grade Group 1 Prostate Cancers Exhibit Tumor-defining Androgen Receptor-driven Programs.Eur Urol2023
37070193PAXIP1 and STAG2 converge to maintain 3D genome architecture and facilitate promoter/enhancer contacts to enable stress hormone-dependent transcription.Nucleic Acids Res2023
37333335A genome-wide CRISPR screen in human prostate cancer cells reveals drivers of macrophage-mediated cell killing and positions AR as a tumor-intrinsic immunomodulator.bioRxiv2023
37397353<i>snHiC</i>: a complete and simplified snakemake pipeline for grouped Hi-C data analysis.Bioinform Adv2023
36900323The Tumor Coagulome as a Transcriptional Target and a Potential Effector of Glucocorticoids in Human Cancers.Cancers (Basel)2023
34446849Integrated analysis of pain, health-related quality of life, and analgesic use in patients with metastatic castration-resistant prostate cancer treated with Radium-223.Prostate Cancer Prostatic Dis2022
35509021Androgen receptor reprogramming demarcates prognostic, context-dependent gene sets in primary and metastatic prostate cancer.Clin Epigenetics2022
35754340Drug-Induced Epigenomic Plasticity Reprograms Circadian Rhythm Regulation to Drive Prostate Cancer toward Androgen Independence.Cancer Discov2022
35523804Comprehensive characterization of pre- and post-treatment samples of breast cancer reveal potential mechanisms of chemotherapy resistance.NPJ Breast Cancer2022
36450752Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential.Nat Commun2022
35871293HDAC1 and PRC2 mediate combinatorial control in SPI1/PU.1-dependent gene repression in murine erythroleukaemia.Nucleic Acids Res2022
36107780Double-strand break toxicity is chromatin context independent.Nucleic Acids Res2022
36107324Prostate Cancer Epigenetic Plasticity and Enhancer Heterogeneity: Molecular Causes, Consequences and Clinical Implications.Adv Exp Med Biol2022
36071171Genetic determinants of chromatin reveal prostate cancer risk mediated by context-dependent gene regulation.Nat Genet2022
36125208Homing in on a Moving Target: Androgen Receptor Cistromic Plasticity in Prostate Cancer.Endocrinology2022
36323660MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling.Nat Commun2022
35918345Ribosome impairment regulates intestinal stem cell identity via ZAKÉ¿ activation.Nat Commun2022
36251389The 5-Hydroxymethylcytosine Landscape of Prostate Cancer.Cancer Res2022
34927791Unexpected gene activation following CRISPR-Cas9-mediated genome editing.EMBO Rep2022
33328650Genomic and phenotypic heterogeneity in prostate cancer.Nat Rev Urol2021
33576154Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases.Mol Oncol2021
33852423Duality of glucocorticoid action in cancer: tumor-suppressor or oncogene?Endocr Relat Cancer2021
33753731Breast adipocyte size associates with ipsilateral invasive breast cancer risk after ductal carcinoma in situ.NPJ Breast Cancer2021
33531470Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer.Nat Commun2021
33751115Androgen and glucocorticoid receptor direct distinct transcriptional programs by receptor-specific and shared DNA binding sites.Nucleic Acids Res2021
34944934Ribociclib Induces Broad Chemotherapy Resistance and EGFR Dependency in ESR1 Wildtype and Mutant Breast Cancer.Cancers (Basel)2021
34737261Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer.Nat Commun2021
34671036IHC-based Ki67 as response biomarker to tamoxifen in breast cancer window trials enrolling premenopausal women.NPJ Breast Cancer2021
34489572An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer.Nat Cell Biol2021
34503156Radium-223 Treatment of Patients with Metastatic Castration Resistant Prostate Cancer: Biomarkers for Stratification and Response Evaluation.Cancers (Basel)2021
34131070The Prognostic Potential of Human Prostate Cancer-Associated Macrophage Subtypes as Revealed by Single-Cell Transcriptomics.Mol Cancer Res2021
34272384Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer.Nat Commun2021
34211036A kinome-centered CRISPR-Cas9 screen identifies activated BRAF to modulate enzalutamide resistance with potential therapeutic implications in BRAF-mutated prostate cancer.Sci Rep2021
34208621TRIMming Down Hormone-Driven Cancers: The Biological Impact of TRIM Proteins on Tumor Development, Progression and Prognostication.Cells2021
33975627Functional mapping of androgen receptor enhancer activity.Genome Biol2021
33462444The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer.Nat Med2021
33452241The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair.Nat Commun2021
33358533Estrogen Receptor on the move: Cistromic plasticity and its implications in breast cancer.Mol Aspects Med2021
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Collaborators

Andries M Bergman
The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital
Co-authored papers 38
Lodewyk F A Wessels
University Medical Centre Mannheim, University of Heidelberg
Co-authored papers 30
Tesa M Severson
Oncode Institute, The Netherlands Cancer Institute
Co-authored papers 17
Jason S Carroll
Co-authored papers 15
Jos Jonkers
Oncode Institute, Netherlands Cancer Institute
Co-authored papers 8
Felix Y Feng
UCSF Medical Center-Mount Zion
Co-authored papers 8
Sander Canisius
The Netherlands Cancer Institute
Co-authored papers 7
Yanyun Zhu
Jiangsu Collaborative Innovation Center for Solid Organic Waste Resource Utilization
Co-authored papers 7
Matthew L Freedman
Dana-Farber Cancer Institute
Co-authored papers 7
Paul J van Diest
University Medical Center Utrecht
Co-authored papers 5
Housheng Hansen He
Princess Margaret Cancer Center, University Health Network, University of Toronto
Co-authored papers 5
Martin E Gleave
University of British Columbia
Co-authored papers 4
Daniel S Peeper
Netherlands Cancer Institute
Co-authored papers 4
Mark M Pomerantz
Dana-Farber Cancer Institute
Co-authored papers 4
Oscar Krijgsman
The Netherlands Cancer Institute
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Sylvan C Baca
Co-authored papers 4
Bogdan Pasaniuc
David Geffen School of Medicine, University of California los angeles
Co-authored papers 4
Himisha Beltran
Dana-Farber Cancer Institute
Co-authored papers 4
Paul C Boutros
University of California los angeles
Co-authored papers 4
Amina Zoubeidi
University of British Columbia
Co-authored papers 4
Takafumi N Yamaguchi
University of California los angeles
Co-authored papers 3
Giacomo Grillo
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Luke A Selth
Adelaide Medical School, University of Adelaide
Co-authored papers 3
Michiel S van der Heijden
the Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital
Co-authored papers 3
Mark A Rubin
University of Bern
Co-authored papers 3
Stanley Zhou
Princess Margaret Cancer Research Centre
Co-authored papers 3
Mohammed Alshalalfa
University of Miami Miller School of Medicine/Sylvester Comprehensive Cancer Center
Co-authored papers 3
Faraz Hach
University of British Columbia
Co-authored papers 3
Michael Fraser
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Carlos Caldas
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